BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 33129109)

  • 1. Enhanced efficacy of JAK1 inhibitor with mTORC1/C2 targeting in smoldering/chronic adult T cell leukemia.
    Daenthanasanmak A; Lin Y; Zhang M; Bryant BR; Petrus MN; Bamford RN; Thomas CJ; Miljkovic MD; Conlon KC; Waldmann TA
    Transl Oncol; 2021 Jan; 14(1):100913. PubMed ID: 33129109
    [TBL] [Abstract][Full Text] [Related]  

  • 2. JAK-STAT and JAK-PI3K-mTORC1 pathways regulate telomerase transcriptionally and posttranslationally in ATL cells.
    Yamada O; Ozaki K; Akiyama M; Kawauchi K
    Mol Cancer Ther; 2012 May; 11(5):1112-21. PubMed ID: 22402124
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia.
    Zhang M; Mathews Griner LA; Ju W; Duveau DY; Guha R; Petrus MN; Wen B; Maeda M; Shinn P; Ferrer M; Conlon KD; Bamford RN; O'Shea JJ; Thomas CJ; Waldmann TA
    Proc Natl Acad Sci U S A; 2015 Oct; 112(40):12480-5. PubMed ID: 26396258
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual inhibition of the mTORC1 and mTORC2 signaling pathways is a promising therapeutic target for adult T-cell leukemia.
    Kawata T; Tada K; Kobayashi M; Sakamoto T; Takiuchi Y; Iwai F; Sakurada M; Hishizawa M; Shirakawa K; Shindo K; Sato H; Takaori-Kondo A
    Cancer Sci; 2018 Jan; 109(1):103-111. PubMed ID: 29077243
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Autocrine/paracrine cytokine stimulation of leukemic cell proliferation in smoldering and chronic adult T-cell leukemia.
    Chen J; Petrus M; Bryant BR; Nguyen VP; Goldman CK; Bamford R; Morris JC; Janik JE; Waldmann TA
    Blood; 2010 Dec; 116(26):5948-56. PubMed ID: 20858854
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in
    Zhang Q; Shi C; Han L; Jain N; Roberts KG; Ma H; Cai T; Cavazos A; Tabe Y; Jacamo RO; Mu H; Zhao Y; Wang J; Wu SC; Cao F; Zeng Z; Zhou J; Mi Y; Jabbour EJ; Levine R; Tasian SK; Mullighan CG; Weinstock DM; Fruman DA; Konopleva M
    Oncotarget; 2018 Jan; 9(8):8027-8041. PubMed ID: 29487712
    [TBL] [Abstract][Full Text] [Related]  

  • 7. IL-2Ralpha-Directed monoclonal antibodies provide effective therapy in a murine model of adult T-cell leukemia by a mechanism other than blockade of IL-2/IL-2Ralpha interaction.
    Phillips KE; Herring B; Wilson LA; Rickford MS; Zhang M; Goldman CK; Tso JY; Waldmann TA
    Cancer Res; 2000 Dec; 60(24):6977-84. PubMed ID: 11156399
    [TBL] [Abstract][Full Text] [Related]  

  • 8. IL-2/IL-2 Receptor Pathway Plays a Crucial Role in the Growth and Malignant Transformation of HTLV-1-Infected T Cells to Develop Adult T-Cell Leukemia.
    Maeda M; Tanabe-Shibuya J; Miyazato P; Masutani H; Yasunaga JI; Usami K; Shimizu A; Matsuoka M
    Front Microbiol; 2020; 11():356. PubMed ID: 32210945
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overview of Targeted Therapies for Adult T-Cell Leukemia/Lymphoma.
    Nasr R; Marçais A; Hermine O; Bazarbachi A
    Methods Mol Biol; 2017; 1582():197-216. PubMed ID: 28357672
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells.
    Uchiyama T; Hori T; Tsudo M; Wano Y; Umadome H; Tamori S; Yodoi J; Maeda M; Sawami H; Uchino H
    J Clin Invest; 1985 Aug; 76(2):446-53. PubMed ID: 2993359
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human T-lymphotropic virus type I proviral loads in patients with adult T-cell leukemia-lymphoma: Comparison between cutaneous type and other subtypes.
    Yonekura K; Utsunomiya A; Seto M; Takatsuka Y; Takeuchi S; Tokunaga M; Kubota A; Takeda K; Kanzaki T; Uchida Y; Kawai K; Kanekura T
    J Dermatol; 2015 Dec; 42(12):1143-8. PubMed ID: 26134467
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Down-regulation of SHP1 and up-regulation of negative regulators of JAK/STAT signaling in HTLV-1 transformed cell lines and freshly transformed human peripheral blood CD4+ T-cells.
    Cheng J; Zhang D; Zhou C; Marasco WA
    Leuk Res; 2004 Jan; 28(1):71-82. PubMed ID: 14630083
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Adult T-cell leukemia-lymphoma.
    Tsukasaki K
    Hematology; 2012 Apr; 17 Suppl 1():S32-5. PubMed ID: 22507774
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human T lymphotropic virus type-I and adult T-cell leukemia in Japan.
    Yamaguchi K; Watanabe T
    Int J Hematol; 2002 Aug; 76 Suppl 2():240-5. PubMed ID: 12430931
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multi-clonal expansion of unique human T-lymphotropic virus type-I-infected T cells with high growth potential in response to interleukin-2 in prodromal phase of adult T cell leukemia.
    Hata T; Fujimoto T; Tsushima H; Murata K; Tsukasaki K; Atogami S; Sohda H; Honda S; Mine M; Yamada Y; Ikeda S; Kamihira S; Tomonaga M
    Leukemia; 1999 Feb; 13(2):215-21. PubMed ID: 10025895
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Superoxide-Generating Nox5α Is Functionally Required for the Human T-Cell Leukemia Virus Type 1-Induced Cell Transformation Phenotype.
    Shigemura T; Shiohara M; Kato M; Furuta S; Kaneda K; Morishita K; Hasegawa H; Fujii M; Gorlach A; Koike K; Kamata T
    J Virol; 2015 Sep; 89(17):9080-9. PubMed ID: 26109726
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interleukin 1 gene expression in adult T cell leukemia.
    Wano Y; Hattori T; Matsuoka M; Takatsuki K; Chua AO; Gubler U; Greene WC
    J Clin Invest; 1987 Sep; 80(3):911-6. PubMed ID: 2887587
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Smoldering adult T-cell leukemia complicated with pneumocystis pneumonia: A case report.
    Kawamoto K; Yamasaki M; Taniwaki M; Itagaki M; Daido W; Matsumoto Y; Matsumoto N; Izumi Y; Otohara M; Ohashi N; Hattori N
    Respir Med Case Rep; 2021; 33():101404. PubMed ID: 34401255
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Adult T cell leukemia-lymphoma (ATL)].
    Tsukasaki K
    Nihon Rinsho; 2014 Mar; 72(3):531-7. PubMed ID: 24724415
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Janus kinase JAK1 maintains the ovarian reserve of primordial follicles in the mouse ovary.
    Sutherland JM; Frost ER; Ford EA; Peters AE; Reed NL; Seldon AN; Mihalas BP; Russel DL; Dunning KR; McLaughlin EA
    Mol Hum Reprod; 2018 Nov; 24(11):533-542. PubMed ID: 30247637
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.