These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Phosphatidylinositol-3-kinase p110γ contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells. Hohenester S; Gates A; Wimmer R; Beuers U; Anwer MS; Rust C; Webster CR J Hepatol; 2010 Nov; 53(5):918-26. PubMed ID: 20675006 [TBL] [Abstract][Full Text] [Related]
4. Bile acid-induced apoptosis and bile acid synthesis are reduced by over-expression of Augmenter of Liver Regeneration (ALR) in a STAT3-dependent mechanism. Ibrahim S; Dayoub R; Krautbauer S; Liebisch G; Wege AK; Melter M; Weiss TS Exp Cell Res; 2019 Jan; 374(1):189-197. PubMed ID: 30500391 [TBL] [Abstract][Full Text] [Related]
5. Hepatocyte growth factor signaling pathway inhibits cholesterol 7alpha-hydroxylase and bile acid synthesis in human hepatocytes. Song KH; Ellis E; Strom S; Chiang JY Hepatology; 2007 Dec; 46(6):1993-2002. PubMed ID: 17924446 [TBL] [Abstract][Full Text] [Related]
6. Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1. Shinohara M; Ybanez MD; Win S; Than TA; Jain S; Gaarde WA; Han D; Kaplowitz N J Biol Chem; 2010 Mar; 285(11):8244-55. PubMed ID: 20061376 [TBL] [Abstract][Full Text] [Related]
7. Canagliflozin, a SGLT-2 inhibitor, relieves ER stress, modulates autophagy and induces apoptosis in irradiated HepG2 cells: Signal transduction between PI3K/AKT/GSK-3β/mTOR and Wnt/β-catenin pathways; Abdel-Rafei MK; Thabet NM; Rashed LA; Moustafa EM J Cancer Res Ther; 2021; 17(6):1404-1418. PubMed ID: 34916371 [TBL] [Abstract][Full Text] [Related]
8. Resistin disrupts glycogen synthesis under high insulin and high glucose levels by down-regulating the hepatic levels of GSK3β. Song R; Wang X; Mao Y; Li H; Li Z; Xu W; Wang R; Guo T; Jin L; Zhang X; Zhang Y; Zhou N; Hu R; Jia J; Lei Z; Irwin DM; Niu G; Tan H Gene; 2013 Oct; 529(1):50-6. PubMed ID: 23860320 [TBL] [Abstract][Full Text] [Related]
9. Hydrophobic bile acid apoptosis is regulated by sphingosine-1-phosphate receptor 2 in rat hepatocytes and human hepatocellular carcinoma cells. Webster CR; Anwer MS Am J Physiol Gastrointest Liver Physiol; 2016 May; 310(10):G865-73. PubMed ID: 26999807 [TBL] [Abstract][Full Text] [Related]
10. IL-6 regulates Mcl-1L expression through the JAK/PI3K/Akt/CREB signaling pathway in hepatocytes: implication of an anti-apoptotic role during liver regeneration. Chou CH; Lai SL; Chen CN; Lee PH; Peng FC; Kuo ML; Lai HS PLoS One; 2013; 8(6):e66268. PubMed ID: 23825534 [TBL] [Abstract][Full Text] [Related]
11. Bile acids down-regulate the expression of Augmenter of Liver Regeneration (ALR) via SHP/HNF4α1 and independent of Egr-1. Ibrahim S; Dayoub R; Melter M; Weiss TS Exp Mol Pathol; 2018 Dec; 105(3):236-242. PubMed ID: 30243934 [TBL] [Abstract][Full Text] [Related]
12. A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene. Li T; Chiang JY Gastroenterology; 2007 Nov; 133(5):1660-9. PubMed ID: 17920062 [TBL] [Abstract][Full Text] [Related]
13. A novel mechanism of hepatocellular carcinoma cell apoptosis induced by lupeol via Brain-Derived Neurotrophic Factor Inhibition and Glycogen Synthase Kinase 3 beta reactivation. Zhang L; Tu Y; He W; Peng Y; Qiu Z Eur J Pharmacol; 2015 Sep; 762():55-62. PubMed ID: 26004524 [TBL] [Abstract][Full Text] [Related]
14. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis. Jiang Y; Liu F; Zou F; Zhang Y; Wang B; Zhang Y; Lian A; Han X; Liu Z; Liu X; Jin M; Wang D; Li G; Liu J Stem Cell Res Ther; 2019 Aug; 10(1):268. PubMed ID: 31443676 [TBL] [Abstract][Full Text] [Related]
15. Role of TLR4-Mediated PI3K/AKT/GSK-3β Signaling Pathway in Apoptosis of Rat Hepatocytes. Zhang X; Jiang D; Jiang W; Zhao M; Gan J Biomed Res Int; 2015; 2015():631326. PubMed ID: 26770978 [TBL] [Abstract][Full Text] [Related]
16. Cleavage and polyadenylation-specific factor 3 induces cell cycle arrest via PI3K/Akt/GSK-3β signaling pathways and predicts a negative prognosis in hepatocellular carcinoma. Li N; Jiang S; Fu R; Lv J; Yao J; Mai J; Hua X; Chen H; Liu J; Lu M Biomark Med; 2021 Apr; 15(5):347-358. PubMed ID: 33666519 [No Abstract] [Full Text] [Related]
17. Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells. Li T; Jahan A; Chiang JY Hepatology; 2006 Jun; 43(6):1202-10. PubMed ID: 16729332 [TBL] [Abstract][Full Text] [Related]
18. Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells. Mottet D; Dumont V; Deccache Y; Demazy C; Ninane N; Raes M; Michiels C J Biol Chem; 2003 Aug; 278(33):31277-85. PubMed ID: 12764143 [TBL] [Abstract][Full Text] [Related]
19. A GAPDH-mediated trans-nitrosylation pathway is required for feedback inhibition of bile salt synthesis in rat liver. Rodríguez-Ortigosa CM; Celay J; Olivas I; Juanarena N; Arcelus S; Uriarte I; Marín JJ; Avila MA; Medina JF; Prieto J Gastroenterology; 2014 Nov; 147(5):1084-93. PubMed ID: 25066374 [TBL] [Abstract][Full Text] [Related]
20. Selective PPARδ agonist seladelpar suppresses bile acid synthesis by reducing hepatocyte CYP7A1 via the fibroblast growth factor 21 signaling pathway. Kouno T; Liu X; Zhao H; Kisseleva T; Cable EE; Schnabl B J Biol Chem; 2022 Jul; 298(7):102056. PubMed ID: 35605662 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]