These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 33137094)

  • 1. Ribosome biogenesis is a downstream effector of the oncogenic U2AF1-S34F mutation.
    Akef A; McGraw K; Cappell SD; Larson DR
    PLoS Biol; 2020 Nov; 18(11):e3000920. PubMed ID: 33137094
    [TBL] [Abstract][Full Text] [Related]  

  • 2. U2AF1 mutation promotes tumorigenicity through facilitating autophagy flux mediated by FOXO3a activation in myelodysplastic syndromes.
    Zhu Y; Song D; Guo J; Jin J; Tao Y; Zhang Z; Xu F; He Q; Li X; Chang C; Wu L
    Cell Death Dis; 2021 Jun; 12(7):655. PubMed ID: 34183647
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene
    Fei DL; Zhen T; Durham B; Ferrarone J; Zhang T; Garrett L; Yoshimi A; Abdel-Wahab O; Bradley RK; Liu P; Varmus H
    Proc Natl Acad Sci U S A; 2018 Oct; 115(44):E10437-E10446. PubMed ID: 30322915
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation.
    Warnasooriya C; Feeney CF; Laird KM; Ermolenko DN; Kielkopf CL
    Nucleic Acids Res; 2020 Jun; 48(10):5695-5709. PubMed ID: 32343311
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
    Shirai CL; White BS; Tripathi M; Tapia R; Ley JN; Ndonwi M; Kim S; Shao J; Carver A; Saez B; Fulton RS; Fronick C; O'Laughlin M; Lagisetti C; Webb TR; Graubert TA; Walter MJ
    Nat Commun; 2017 Jan; 8():14060. PubMed ID: 28067246
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies.
    Biancon G; Joshi P; Zimmer JT; Hunck T; Gao Y; Lessard MD; Courchaine E; Barentine AES; Machyna M; Botti V; Qin A; Gbyli R; Patel A; Song Y; Kiefer L; Viero G; Neuenkirchen N; Lin H; Bewersdorf J; Simon MD; Neugebauer KM; Tebaldi T; Halene S
    Mol Cell; 2022 Mar; 82(6):1107-1122.e7. PubMed ID: 35303483
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice.
    Kim SP; Srivatsan SN; Chavez M; Shirai CL; White BS; Ahmed T; Alberti MO; Shao J; Nunley R; White LS; Bednarski J; Pehrson JR; Walter MJ
    Cell Rep; 2021 Aug; 36(9):109626. PubMed ID: 34469727
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo.
    Shirai CL; Ley JN; White BS; Kim S; Tibbitts J; Shao J; Ndonwi M; Wadugu B; Duncavage EJ; Okeyo-Owuor T; Liu T; Griffith M; McGrath S; Magrini V; Fulton RS; Fronick C; O'Laughlin M; Graubert TA; Walter MJ
    Cancer Cell; 2015 May; 27(5):631-43. PubMed ID: 25965570
    [TBL] [Abstract][Full Text] [Related]  

  • 9. U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing.
    Okeyo-Owuor T; White BS; Chatrikhi R; Mohan DR; Kim S; Griffith M; Ding L; Ketkar-Kulkarni S; Hundal J; Laird KM; Kielkopf CL; Ley TJ; Walter MJ; Graubert TA
    Leukemia; 2015 Apr; 29(4):909-17. PubMed ID: 25311244
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis.
    Gurule NJ; Malcolm KC; Harris C; Knapp JR; O'Connor BP; McClendon J; Janssen WJ; Lee FFY; Price C; Osaghae-Nosa J; Wheeler EA; McMahon CM; Pietras EM; Pollyea DA; Alper S
    Leukemia; 2023 Oct; 37(10):2115-2124. PubMed ID: 37591942
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Prognostic value of U2AF1 mutant in patients with de novo myelodysplastic syndromes: a meta-analysis.
    Wang H; Zhang N; Wu X; Zheng X; Ling Y; Gong Y
    Ann Hematol; 2019 Dec; 98(12):2629-2639. PubMed ID: 31754743
    [TBL] [Abstract][Full Text] [Related]  

  • 12. U2AF35(S34F) Promotes Transformation by Directing Aberrant ATG7 Pre-mRNA 3' End Formation.
    Park SM; Ou J; Chamberlain L; Simone TM; Yang H; Virbasius CM; Ali AM; Zhu LJ; Mukherjee S; Raza A; Green MR
    Mol Cell; 2016 May; 62(4):479-90. PubMed ID: 27184077
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation.
    Palangat M; Anastasakis DG; Fei DL; Lindblad KE; Bradley R; Hourigan CS; Hafner M; Larson DR
    Genes Dev; 2019 May; 33(9-10):482-497. PubMed ID: 30842218
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Decreased CD177
    Alayed K; Meyerson HJ
    Leuk Res; 2022 Jan; 112():106752. PubMed ID: 34896936
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential U2AF1 mutation sites, burden and co-mutation genes can predict prognosis in patients with myelodysplastic syndrome.
    Wang H; Guo Y; Dong Z; Li T; Xie X; Wan D; Jiang Z; Yu J; Guo R
    Sci Rep; 2020 Oct; 10(1):18622. PubMed ID: 33122737
    [TBL] [Abstract][Full Text] [Related]  

  • 16. U2AF1 pathogenic variants in myeloid neoplasms and precursor states: distribution of co-mutations and prognostic heterogeneity.
    Badar T; Vanegas YAM; Nanaa A; Foran JM; Al-Kali A; Mangaonkar A; Murthy H; Alkhateeb HB; Viswanatha D; He R; Shah M; Yi CA; Litzow MR; Gangat N; Tefferi A; Patnaik MM
    Blood Cancer J; 2023 Sep; 13(1):149. PubMed ID: 37735430
    [TBL] [Abstract][Full Text] [Related]  

  • 17. U2AF1 mutations in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome.
    Qian J; Yao DM; Lin J; Qian W; Wang CZ; Chai HY; Yang J; Li Y; Deng ZQ; Ma JC; Chen XX
    PLoS One; 2012; 7(9):e45760. PubMed ID: 23029227
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional significance of U2AF1 S34F mutations in lung adenocarcinomas.
    Esfahani MS; Lee LJ; Jeon YJ; Flynn RA; Stehr H; Hui AB; Ishisoko N; Kildebeck E; Newman AM; Bratman SV; Porteus MH; Chang HY; Alizadeh AA; Diehn M
    Nat Commun; 2019 Dec; 10(1):5712. PubMed ID: 31836708
    [TBL] [Abstract][Full Text] [Related]  

  • 19. U2AF1 mutation connects DNA damage to the alternative splicing of RAD51 in lung adenocarcinomas.
    Chen C; Zhou P; Zhang Z; Liu Y
    Clin Exp Pharmacol Physiol; 2022 Jul; 49(7):740-747. PubMed ID: 35434831
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression.
    Pan WA; Tsai HY; Wang SC; Hsiao M; Wu PY; Tsai MD
    RNA Biol; 2015; 12(3):255-67. PubMed ID: 25826659
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.