BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 33142414)

  • 1. Discovery of novel artemisinin-sulfonamidehybrids as potential carbonicanhydraseIX inhibitors with improved antiproliferative activities.
    An R; Lin B; Zhao S; Cao C; Wang Y; Cheng X; Liu Y; Guo M; Xu H; Wang Y; Hou Z; Guo C
    Bioorg Chem; 2020 Nov; 104():104347. PubMed ID: 33142414
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform.
    Ibrahim HS; Allam HA; Mahmoud WR; Bonardi A; Nocentini A; Gratteri P; Ibrahim ES; Abdel-Aziz HA; Supuran CT
    Eur J Med Chem; 2018 May; 152():1-9. PubMed ID: 29684705
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and biological evaluation of novel carbohydrate-based sulfonamide derivatives as antitumor agents.
    Hao S; Cheng X; Wang X; An R; Xu H; Guo M; Li C; Wang Y; Hou Z; Guo C
    Bioorg Chem; 2020 Nov; 104():104237. PubMed ID: 32911194
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of coumarin-sulfonamide derivatives and determination of their cytotoxicity, carbonic anhydrase inhibitory and molecular docking studies.
    Zengin Kurt B; Sonmez F; Ozturk D; Akdemir A; Angeli A; Supuran CT
    Eur J Med Chem; 2019 Dec; 183():111702. PubMed ID: 31542715
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inclusion of a 5-fluorouracil moiety in nitrogenous bases derivatives as human carbonic anhydrase IX and XII inhibitors produced a targeted action against MDA-MB-231 and T47D breast cancer cells.
    Petreni A; Bonardi A; Lomelino C; Osman SM; ALOthman ZA; Eldehna WM; El-Haggar R; McKenna R; Nocentini A; Supuran CT
    Eur J Med Chem; 2020 Mar; 190():112112. PubMed ID: 32044580
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII.
    Akocak S; Güzel-Akdemir Ö; Kishore Kumar Sanku R; Russom SS; Iorga BI; Supuran CT; Ilies MA
    Bioorg Chem; 2020 Oct; 103():104204. PubMed ID: 32891000
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Iodoquinazolinones bearing benzenesulfonamide as human carbonic anhydrase I, II, IX and XII inhibitors: Synthesis, biological evaluation and radiosensitizing activity.
    Soliman AM; Ghorab MM; Bua S; Supuran CT
    Eur J Med Chem; 2020 Aug; 200():112449. PubMed ID: 32485534
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Investigation of 3-sulfamoyl coumarins against cancer-related IX and XII isoforms of human carbonic anhydrase as well as cancer cells leads to the discovery of 2-oxo-2H-benzo[h]chromene-3-sulfonamide - A new caspase-activating proapoptotic agent.
    Dar'in D; Kantin G; Kalinin S; Sharonova T; Bunev A; Ostapenko GI; Nocentini A; Sharoyko V; Supuran CT; Krasavin M
    Eur J Med Chem; 2021 Oct; 222():113589. PubMed ID: 34147910
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Application of the dual-tail approach for the design and synthesis of novel Thiopyrimidine-Benzenesulfonamide hybrids as selective carbonic anhydrase inhibitors.
    Abdel-Mohsen HT; El Kerdawy AM; Omar MA; Petreni A; Allam RM; El Diwani HI; Supuran CT
    Eur J Med Chem; 2022 Jan; 228():114004. PubMed ID: 34847409
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer activity, and molecular modeling studies.
    Żołnowska B; Sławiński J; Szafrański K; Angeli A; Supuran CT; Kawiak A; Wieczór M; Zielińska J; Bączek T; Bartoszewska S
    Eur J Med Chem; 2018 Jan; 143():1931-1941. PubMed ID: 29146134
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and
    Abdelrahman MA; Eldehna WM; Nocentini A; Ibrahim HS; Almahli H; Abdel-Aziz HA; Abou-Seri SM; Supuran CT
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):298-305. PubMed ID: 31809607
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IX.
    Allam HA; Fahim SH; F Abo-Ashour M; Nocentini A; Elbakry ME; Abdelrahman MA; Eldehna WM; Ibrahim HS; Supuran CT
    Eur J Med Chem; 2019 Oct; 179():547-556. PubMed ID: 31276899
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insertion of metal carbenes into the anilinic N-H bond of unprotected aminobenzenesulfonamides delivers low nanomolar inhibitors of human carbonic anhydrase IX and XII isoforms.
    Sharonova T; Paramonova P; Kalinin S; Bunev A; Gasanov RЕ; Nocentini A; Sharoyko V; Tennikova TB; Dar'in D; Supuran CT; Krasavin M
    Eur J Med Chem; 2021 Jun; 218():113352. PubMed ID: 33774343
    [TBL] [Abstract][Full Text] [Related]  

  • 14. S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors.
    El-Azab AS; Abdel-Aziz AA; Bua S; Nocentini A; AlSaif NA; Alanazi MM; El-Gendy MA; Ahmed HEA; Supuran CT
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):733-743. PubMed ID: 32189526
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors.
    Gul HI; Yamali C; Sakagami H; Angeli A; Leitans J; Kazaks A; Tars K; Ozgun DO; Supuran CT
    Bioorg Chem; 2018 Apr; 77():411-419. PubMed ID: 29427856
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.
    Dvořanová J; Kugler M; Holub J; Šícha V; Das V; Nekvinda J; El Anwar S; Havránek M; Pospíšilová K; Fábry M; Král V; Medvedíková M; Matějková S; Lišková B; Gurská S; Džubák P; Brynda J; Hajdúch M; Grüner B; Řezáčová P
    Eur J Med Chem; 2020 Aug; 200():112460. PubMed ID: 32505851
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, biological activity and multiscale molecular modeling studies of bis-coumarins as selective carbonic anhydrase IX and XII inhibitors with effective cytotoxicity against hepatocellular carcinoma.
    Kurt BZ; Dag A; Doğan B; Durdagi S; Angeli A; Nocentini A; Supuran CT; Sonmez F
    Bioorg Chem; 2019 Jun; 87():838-850. PubMed ID: 31003041
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation.
    Said MA; Eldehna WM; Nocentini A; Fahim SH; Bonardi A; Elgazar AA; Kryštof V; Soliman DH; Abdel-Aziz HA; Gratteri P; Abou-Seri SM; Supuran CT
    Eur J Med Chem; 2020 Mar; 189():112019. PubMed ID: 31972394
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of curcumin inspired sulfonamide derivatives as a new class of carbonic anhydrase isoforms I, II, IX, and XII inhibitors.
    Ramya PVS; Angapelly S; Angeli A; Digwal CS; Arifuddin M; Babu BN; Supuran CT; Kamal A
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):1274-1281. PubMed ID: 28965419
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors.
    Yamali C; Gul HI; Ece A; Bua S; Angeli A; Sakagami H; Sahin E; Supuran CT
    Bioorg Chem; 2019 Nov; 92():103222. PubMed ID: 31499260
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.