These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

481 related articles for article (PubMed ID: 33142929)

  • 1. Regulation of CAR and PXR Expression in Health and Disease.
    Daujat-Chavanieu M; Gerbal-Chaloin S
    Cells; 2020 Oct; 9(11):. PubMed ID: 33142929
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PXR and CAR in energy metabolism.
    Wada T; Gao J; Xie W
    Trends Endocrinol Metab; 2009 Aug; 20(6):273-9. PubMed ID: 19595610
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.
    Kast HR; Goodwin B; Tarr PT; Jones SA; Anisfeld AM; Stoltz CM; Tontonoz P; Kliewer S; Willson TM; Edwards PA
    J Biol Chem; 2002 Jan; 277(4):2908-15. PubMed ID: 11706036
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
    Maglich JM; Stoltz CM; Goodwin B; Hawkins-Brown D; Moore JT; Kliewer SA
    Mol Pharmacol; 2002 Sep; 62(3):638-46. PubMed ID: 12181440
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
    Kandel BA; Thomas M; Winter S; Damm G; Seehofer D; Burk O; Schwab M; Zanger UM
    Biochim Biophys Acta; 2016 Sep; 1859(9):1218-1227. PubMed ID: 26994748
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ligand recognition by drug-activated nuclear receptors PXR and CAR: structural, site-directed mutagenesis and molecular modeling studies.
    Poso A; Honkakoski P
    Mini Rev Med Chem; 2006 Aug; 6(8):937-47. PubMed ID: 16918499
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Allyl isothiocyanate (AITC) inhibits pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation and protects against acetaminophen- and amiodarone-induced cytotoxicity.
    Lim YP; Cheng CH; Chen WC; Chang SY; Hung DZ; Chen JJ; Wan L; Ma WC; Lin YH; Chen CY; Yokoi T; Nakajima M; Chen CJ
    Arch Toxicol; 2015 Jan; 89(1):57-72. PubMed ID: 25069801
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic variants of PXR (NR1I2) and CAR (NR1I3) and their implications in drug metabolism and pharmacogenetics.
    Lamba J; Lamba V; Schuetz E
    Curr Drug Metab; 2005 Aug; 6(4):369-83. PubMed ID: 16101575
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
    Zhang J; Huang W; Qatanani M; Evans RM; Moore DD
    J Biol Chem; 2004 Nov; 279(47):49517-22. PubMed ID: 15358766
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes.
    Moscovitz JE; Kalgutkar AS; Nulick K; Johnson N; Lin Z; Goosen TC; Weng Y
    J Pharmacol Exp Ther; 2018 May; 365(2):262-271. PubMed ID: 29440451
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
    Moore LB; Parks DJ; Jones SA; Bledsoe RK; Consler TG; Stimmel JB; Goodwin B; Liddle C; Blanchard SG; Willson TM; Collins JL; Kliewer SA
    J Biol Chem; 2000 May; 275(20):15122-7. PubMed ID: 10748001
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
    Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
    Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase.
    Echchgadda I; Song CS; Oh T; Ahmed M; De La Cruz IJ; Chatterjee B
    Mol Endocrinol; 2007 Sep; 21(9):2099-111. PubMed ID: 17595319
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
    Hu Q; Yao N; Wu J; Liu M; Liu F; Zhang H; Xiong Y; Xia C
    Biochem Pharmacol; 2019 Jan; 159():32-39. PubMed ID: 30414935
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter.
    Ding X; Staudinger JL
    J Pharmacol Exp Ther; 2005 Jul; 314(1):120-7. PubMed ID: 15833898
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
    Tirona RG; Lee W; Leake BF; Lan LB; Cline CB; Lamba V; Parviz F; Duncan SA; Inoue Y; Gonzalez FJ; Schuetz EG; Kim RB
    Nat Med; 2003 Feb; 9(2):220-4. PubMed ID: 12514743
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.
    Küblbeck J; Zancanella V; Prantner V; Molnár F; Squires EJ; Dacasto M; Honkakoski P; Giantin M
    Xenobiotica; 2016; 46(3):200-10. PubMed ID: 26153444
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Xenosensors CAR and PXR at work: impact on statin metabolism.
    Marino M; di Masi A; Trezza V; Pallottini V; Polticelli F; Ascenzi P
    Curr Drug Metab; 2011 Mar; 12(3):300-11. PubMed ID: 21395534
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis.
    Wahlang B; Prough RA; Falkner KC; Hardesty JE; Song M; Clair HB; Clark BJ; States JC; Arteel GE; Cave MC
    Toxicol Sci; 2016 Feb; 149(2):396-410. PubMed ID: 26612838
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
    Roth A; Looser R; Kaufmann M; Blättler SM; Rencurel F; Huang W; Moore DD; Meyer UA
    Mol Pharmacol; 2008 Apr; 73(4):1282-9. PubMed ID: 18187584
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.