These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

497 related articles for article (PubMed ID: 33142929)

  • 21. Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes.
    Moscovitz JE; Kalgutkar AS; Nulick K; Johnson N; Lin Z; Goosen TC; Weng Y
    J Pharmacol Exp Ther; 2018 May; 365(2):262-271. PubMed ID: 29440451
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Distinct Roles of the Sister Nuclear Receptors PXR and CAR in Liver Cancer Development.
    Yoshinari K; Shizu R
    Drug Metab Dispos; 2022 Jul; 50(7):1019-1026. PubMed ID: 35184041
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
    Moore LB; Parks DJ; Jones SA; Bledsoe RK; Consler TG; Stimmel JB; Goodwin B; Liddle C; Blanchard SG; Willson TM; Collins JL; Kliewer SA
    J Biol Chem; 2000 May; 275(20):15122-7. PubMed ID: 10748001
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase.
    Echchgadda I; Song CS; Oh T; Ahmed M; De La Cruz IJ; Chatterjee B
    Mol Endocrinol; 2007 Sep; 21(9):2099-111. PubMed ID: 17595319
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter.
    Ding X; Staudinger JL
    J Pharmacol Exp Ther; 2005 Jul; 314(1):120-7. PubMed ID: 15833898
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
    Hu Q; Yao N; Wu J; Liu M; Liu F; Zhang H; Xiong Y; Xia C
    Biochem Pharmacol; 2019 Jan; 159():32-39. PubMed ID: 30414935
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.
    Chen Y; Tang Y; Guo C; Wang J; Boral D; Nie D
    Biochem Pharmacol; 2012 Apr; 83(8):1112-26. PubMed ID: 22326308
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation.
    Bwayi MN; Garcia-Maldonado E; Chai SC; Xie B; Chodankar S; Huber AD; Wu J; Annu K; Wright WC; Lee HM; Seetharaman J; Wang J; Buchman CD; Peng J; Chen T
    Nucleic Acids Res; 2022 Apr; 50(6):3254-3275. PubMed ID: 35212371
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The aldo-keto reductase Akr1b7 gene is a common transcriptional target of xenobiotic receptors pregnane X receptor and constitutive androstane receptor.
    Liu MJ; Takahashi Y; Wada T; He J; Gao J; Tian Y; Li S; Xie W
    Mol Pharmacol; 2009 Sep; 76(3):604-11. PubMed ID: 19542321
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.
    Park YJ; Lee EK; Lee YK; Park DJ; Jang HC; Moore DD
    Toxicol Appl Pharmacol; 2012 Sep; 263(2):131-7. PubMed ID: 22503787
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R; Benoki S; Numakura Y; Kodama S; Miyata M; Yamazoe Y; Yoshinari K
    PLoS One; 2013; 8(4):e61802. PubMed ID: 23626729
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response.
    Scheer N; Ross J; Rode A; Zevnik B; Niehaves S; Faust N; Wolf CR
    J Clin Invest; 2008 Sep; 118(9):3228-39. PubMed ID: 18677425
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.
    Küblbeck J; Zancanella V; Prantner V; Molnár F; Squires EJ; Dacasto M; Honkakoski P; Giantin M
    Xenobiotica; 2016; 46(3):200-10. PubMed ID: 26153444
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice.
    Ohbuchi M; Yoshinari K; Kaneko H; Matsumoto S; Inoue A; Kawamura A; Usui T; Yamazoe Y
    Antimicrob Agents Chemother; 2013 Mar; 57(3):1332-8. PubMed ID: 23274663
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
    Tirona RG; Lee W; Leake BF; Lan LB; Cline CB; Lamba V; Parviz F; Duncan SA; Inoue Y; Gonzalez FJ; Schuetz EG; Kim RB
    Nat Med; 2003 Feb; 9(2):220-4. PubMed ID: 12514743
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis.
    Wahlang B; Prough RA; Falkner KC; Hardesty JE; Song M; Clair HB; Clark BJ; States JC; Arteel GE; Cave MC
    Toxicol Sci; 2016 Feb; 149(2):396-410. PubMed ID: 26612838
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor.
    Kohalmy K; Tamási V; Kóbori L; Sárváry E; Pascussi JM; Porrogi P; Rozman D; Prough RA; Meyer UA; Monostory K
    Drug Metab Dispos; 2007 Sep; 35(9):1495-501. PubMed ID: 17591676
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Xenosensors CAR and PXR at work: impact on statin metabolism.
    Marino M; di Masi A; Trezza V; Pallottini V; Polticelli F; Ascenzi P
    Curr Drug Metab; 2011 Mar; 12(3):300-11. PubMed ID: 21395534
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
    Roth A; Looser R; Kaufmann M; Blättler SM; Rencurel F; Huang W; Moore DD; Meyer UA
    Mol Pharmacol; 2008 Apr; 73(4):1282-9. PubMed ID: 18187584
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene.
    Krausova L; Stejskalova L; Wang H; Vrzal R; Dvorak Z; Mani S; Pavek P
    Biochem Pharmacol; 2011 Dec; 82(11):1771-80. PubMed ID: 21920351
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 25.