BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 33149807)

  • 1. Antitumor Therapy under Hypoxic Microenvironment by the Combination of 2-Methoxyestradiol and Sodium Dichloroacetate on Human Non-Small-Cell Lung Cancer.
    Romero Y; Castillejos-López M; Romero-García S; Aguayo AS; Herrera I; Garcia-Martin MO; Torres-Espíndola LM; Negrete-García MC; Olvera AC; Huerta-Cruz JC; Cruz RV; Cisneros J; Soto EF; Solís-Chagoyán H; Mendoza-Milla C; Cabello-Gutiérrez C; Ruiz V; Aquino-Gálvez A
    Oxid Med Cell Longev; 2020; 2020():3176375. PubMed ID: 33149807
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia.
    Aquino-Gálvez A; González-Ávila G; Delgado-Tello J; Castillejos-López M; Mendoza-Milla C; Zúñiga J; Checa M; Maldonado-Martínez HA; Trinidad-López A; Cisneros J; Torres-Espíndola LM; Hernández-Jiménez C; Sommer B; Cabello-Gutiérrez C; Gutiérrez-González LH
    Oncol Rep; 2016 Jan; 35(1):577-83. PubMed ID: 26548300
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allicin Overcomes Hypoxia Mediated Cisplatin Resistance in Lung Cancer Cells through ROS Mediated Cell Death Pathway and by Suppressing Hypoxia Inducible Factors.
    Pandey N; Tyagi G; Kaur P; Pradhan S; Rajam MV; Srivastava T
    Cell Physiol Biochem; 2020 Aug; 54(4):748-766. PubMed ID: 32809300
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-Methoxyestradiol synergizes with Erlotinib to suppress hepatocellular carcinoma by disrupting the PLAGL2-EGFR-HIF-1/2α signaling loop.
    Zheng S; Ni J; Li Y; Lu M; Yao Y; Guo H; Jiao M; Jin T; Zhang H; Yuan A; Wang Z; Yang Y; Chen Z; Wu H; Hu W
    Pharmacol Res; 2021 Jul; 169():105685. PubMed ID: 34022398
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2-Methoxyestradiol synergizes with sorafenib to suppress hepatocellular carcinoma by simultaneously dysregulating hypoxia-inducible factor-1 and -2.
    Ma L; Li G; Zhu H; Dong X; Zhao D; Jiang X; Li J; Qiao H; Ni S; Sun X
    Cancer Lett; 2014 Dec; 355(1):96-105. PubMed ID: 25218350
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dichloroacetate alters Warburg metabolism, inhibits cell growth, and increases the X-ray sensitivity of human A549 and H1299 NSC lung cancer cells.
    Allen KT; Chin-Sinex H; DeLuca T; Pomerening JR; Sherer J; Watkins JB; Foley J; Jesseph JM; Mendonca MS
    Free Radic Biol Med; 2015 Dec; 89():263-73. PubMed ID: 26393423
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Acidosis-induced metabolic reprogramming in tumor cells enhances the anti-proliferative activity of the PDK inhibitor dichloroacetate.
    Schoonjans CA; Joudiou N; Brusa D; Corbet C; Feron O; Gallez B
    Cancer Lett; 2020 Feb; 470():18-28. PubMed ID: 31812695
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The crosstalk between HIFs and mitochondrial dysfunctions in cancer development.
    Bao X; Zhang J; Huang G; Yan J; Xu C; Dou Z; Sun C; Zhang H
    Cell Death Dis; 2021 Feb; 12(2):215. PubMed ID: 33637686
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolic Modulation of Clear-cell Renal Cell Carcinoma with Dichloroacetate, an Inhibitor of Pyruvate Dehydrogenase Kinase.
    Kinnaird A; Dromparis P; Saleme B; Gurtu V; Watson K; Paulin R; Zervopoulos S; Stenson T; Sutendra G; Pink DB; Carmine-Simmen K; Moore R; Lewis JD; Michelakis ED
    Eur Urol; 2016 Apr; 69(4):734-744. PubMed ID: 26433571
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models.
    Neveu MA; De Preter G; Joudiou N; Bol A; Brender JR; Saito K; Kishimoto S; Grégoire V; Jordan BF; Krishna MC; Feron O; Gallez B
    Oncotarget; 2016 Dec; 7(49):81741-81749. PubMed ID: 28082726
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells.
    Zeng L; Zhou HY; Tang NN; Zhang WF; He GJ; Hao B; Feng YD; Zhu H
    World J Gastroenterol; 2016 May; 22(20):4868-80. PubMed ID: 27239113
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Albendazole inhibits HIF-1α-dependent glycolysis and VEGF expression in non-small cell lung cancer cells.
    Zhou F; Du J; Wang J
    Mol Cell Biochem; 2017 Apr; 428(1-2):171-178. PubMed ID: 28063005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Decursin promotes HIF-1α proteasomal degradation and immune responses in hypoxic tumour microenvironment.
    Ge Y; Yoon SH; Jang H; Jeong JH; Lee YM
    Phytomedicine; 2020 Nov; 78():153318. PubMed ID: 32896707
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Restricting tumor lactic acid metabolism using dichloroacetate improves T cell functions.
    Rostamian H; Khakpoor-Koosheh M; Jafarzadeh L; Masoumi E; Fallah-Mehrjardi K; Tavassolifar MJ; M Pawelek J; Mirzaei HR; Hadjati J
    BMC Cancer; 2022 Jan; 22(1):39. PubMed ID: 34991504
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia-mediated drug resistance: novel insights on the functional interaction of HIFs and cell death pathways.
    Rohwer N; Cramer T
    Drug Resist Updat; 2011 Jun; 14(3):191-201. PubMed ID: 21466972
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage differentiation.
    Kumar A; Kant S; Singh SM
    Toxicol Appl Pharmacol; 2013 Nov; 273(1):196-208. PubMed ID: 24051182
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of dichloroacetate on Lewis lung carcinoma growth and metastasis.
    Kolesnik DL; Pyaskovskaya ON; Boychuk IV; Dasyukevich OI; Melnikov OR; Tarasov AS; Solyanik GI
    Exp Oncol; 2015 Jun; 37(2):126-9. PubMed ID: 26112940
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoxia promotes acquisition of aggressive phenotypes in human malignant mesothelioma.
    Kim MC; Hwang SH; Kim NY; Lee HS; Ji S; Yang Y; Kim Y
    BMC Cancer; 2018 Aug; 18(1):819. PubMed ID: 30111297
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential regulation of HIF-mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts.
    Morten KJ; Badder L; Knowles HJ
    J Pathol; 2013 Apr; 229(5):755-64. PubMed ID: 23303559
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Propofol suppresses LPS-induced nuclear accumulation of HIF-1α and tumor aggressiveness in non-small cell lung cancer.
    Yang N; Liang Y; Yang P; Ji F
    Oncol Rep; 2017 May; 37(5):2611-2619. PubMed ID: 28426124
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.