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9. Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells. Dolatshad H; Pellagatti A; Fernandez-Mercado M; Yip BH; Malcovati L; Attwood M; Przychodzen B; Sahgal N; Kanapin AA; Lockstone H; Scifo L; Vandenberghe P; Papaemmanuil E; Smith CW; Campbell PJ; Ogawa S; Maciejewski JP; Cazzola M; Savage KI; Boultwood J Leukemia; 2015 May; 29(5):1092-103. PubMed ID: 25428262 [TBL] [Abstract][Full Text] [Related]
10. SF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeast. Carrocci TJ; Zoerner DM; Paulson JC; Hoskins AA Nucleic Acids Res; 2017 May; 45(8):4837-4852. PubMed ID: 28062854 [TBL] [Abstract][Full Text] [Related]
11. Physiologic Expression of Sf3b1(K700E) Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation. Obeng EA; Chappell RJ; Seiler M; Chen MC; Campagna DR; Schmidt PJ; Schneider RK; Lord AM; Wang L; Gambe RG; McConkey ME; Ali AM; Raza A; Yu L; Buonamici S; Smith PG; Mullally A; Wu CJ; Fleming MD; Ebert BL Cancer Cell; 2016 Sep; 30(3):404-417. PubMed ID: 27622333 [TBL] [Abstract][Full Text] [Related]
12. Splicing factor mutations in the myelodysplastic syndromes: target genes and therapeutic approaches. Armstrong RN; Steeples V; Singh S; Sanchi A; Boultwood J; Pellagatti A Adv Biol Regul; 2018 Jan; 67():13-29. PubMed ID: 28986033 [TBL] [Abstract][Full Text] [Related]
13. Altered splicing and cytoplasmic levels of tRNA synthetases in SF3B1-mutant myelodysplastic syndromes as a therapeutic vulnerability. Liberante FG; Lappin K; Barros EM; Vohhodina J; Grebien F; Savage KI; Mills KI Sci Rep; 2019 Feb; 9(1):2678. PubMed ID: 30804405 [TBL] [Abstract][Full Text] [Related]
14. Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations. Aslan D; Garde C; Nygaard MK; Helbo AS; Dimopoulos K; Hansen JW; Severinsen MT; Treppendahl MB; Sjø LD; Grønbæk K; Kristensen LS Oncotarget; 2016 Mar; 7(9):9951-63. PubMed ID: 26848861 [TBL] [Abstract][Full Text] [Related]
15. Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations. Choudhary GS; Pellagatti A; Agianian B; Smith MA; Bhagat TD; Gordon-Mitchell S; Sahu S; Pandey S; Shah N; Aluri S; Aggarwal R; Aminov S; Schwartz L; Steeples V; Booher RN; Ramachandra M; Samson M; Carbajal M; Pradhan K; Bowman TV; Pillai MM; Will B; Wickrema A; Shastri A; Bradley RK; Martell RE; Steidl UG; Gavathiotis E; Boultwood J; Starczynowski DT; Verma A Elife; 2022 Aug; 11():. PubMed ID: 36040792 [TBL] [Abstract][Full Text] [Related]
16. A two-step approach for sequencing spliceosome-related genes as a complementary diagnostic assay in MDS patients with ringed sideroblasts. Janusz K; Del Rey M; Abáigar M; Collado R; Ivars D; Hernández-Sánchez M; Valiente A; Robledo C; Benito R; Díez-Campelo M; Ramos F; Kohlmann A; Cañizo CD; Hernández-Rivas JM Leuk Res; 2017 May; 56():82-87. PubMed ID: 28222336 [TBL] [Abstract][Full Text] [Related]
17. Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts. Mupo A; Seiler M; Sathiaseelan V; Pance A; Yang Y; Agrawal AA; Iorio F; Bautista R; Pacharne S; Tzelepis K; Manes N; Wright P; Papaemmanuil E; Kent DG; Campbell PC; Buonamici S; Bolli N; Vassiliou GS Leukemia; 2017 Mar; 31(3):720-727. PubMed ID: 27604819 [TBL] [Abstract][Full Text] [Related]
18. Clinical Outcomes With Ring Sideroblasts and SF3B1 Mutations in Myelodysplastic Syndromes: MDS Clinical Research Consortium Analysis. Migdady Y; Barnard J; Al Ali N; Steensma DP; DeZern A; Roboz G; Garcia-Manero G; Sekeres MA; Komrokji RS Clin Lymphoma Myeloma Leuk; 2018 Aug; 18(8):528-532. PubMed ID: 29937400 [TBL] [Abstract][Full Text] [Related]
19. Prognostic value and clinical feature of SF3B1 mutations in myelodysplastic syndromes: A meta-analysis. Tang Y; Miao M; Han S; Qi J; Wang H; Ruan C; Wu D; Han Y Crit Rev Oncol Hematol; 2019 Jan; 133():74-83. PubMed ID: 30661660 [TBL] [Abstract][Full Text] [Related]
20. The Frequency of SF3B1 Mutations in Thai Patients with Myelodysplastic Syndrome. Rujirachaivej P; Siriboonpiputtana T; Rerkamnuaychoke B; Magmuang S; Chareonsirisuthigul T; Boonsakan P; Petvises S; Sirirat T; Niparuck P; Chuncharunee S Asian Pac J Cancer Prev; 2018 Jul; 19(7):1825-1831. PubMed ID: 30049194 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]