BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

357 related articles for article (PubMed ID: 33157014)

  • 1. Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity.
    Yao Y; Hong S; Ikeda T; Mori H; MacDougald OA; Nada S; Okada M; Inoki K
    Mol Cell; 2020 Nov; 80(3):437-451.e6. PubMed ID: 33157014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.
    Sancak Y; Bar-Peled L; Zoncu R; Markhard AL; Nada S; Sabatini DM
    Cell; 2010 Apr; 141(2):290-303. PubMed ID: 20381137
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Weak membrane interactions allow Rheb to activate mTORC1 signaling without major lysosome enrichment.
    Angarola B; Ferguson SM
    Mol Biol Cell; 2019 Oct; 30(22):2750-2760. PubMed ID: 31532697
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetic dissection of Ragulator structure and function in amino acid-dependent regulation of mTORC1.
    Nada S; Okada M
    J Biochem; 2020 Dec; 168(6):621-632. PubMed ID: 32653916
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
    Oshiro N; Rapley J; Avruch J
    J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Amino Acid-Mediated Intracellular Ca
    Amemiya Y; Nakamura N; Ikeda N; Sugiyama R; Ishii C; Maki M; Shibata H; Takahara T
    Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34198993
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amino acid regulation of TOR complex 1.
    Avruch J; Long X; Ortiz-Vega S; Rapley J; Papageorgiou A; Dai N
    Am J Physiol Endocrinol Metab; 2009 Apr; 296(4):E592-602. PubMed ID: 18765678
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dynamin-dependent amino acid endocytosis activates mechanistic target of rapamycin complex 1 (mTORC1).
    Shibutani S; Okazaki H; Iwata H
    J Biol Chem; 2017 Nov; 292(44):18052-18061. PubMed ID: 28808055
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.
    Jung J; Genau HM; Behrends C
    Mol Cell Biol; 2015 Jul; 35(14):2479-94. PubMed ID: 25963655
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling.
    Wang X; Fonseca BD; Tang H; Liu R; Elia A; Clemens MJ; Bommer UA; Proud CG
    J Biol Chem; 2008 Nov; 283(45):30482-92. PubMed ID: 18676370
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.
    Carroll B; Maetzel D; Maddocks OD; Otten G; Ratcliff M; Smith GR; Dunlop EA; Passos JF; Davies OR; Jaenisch R; Tee AR; Sarkar S; Korolchuk VI
    Elife; 2016 Jan; 5():. PubMed ID: 26742086
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb.
    Shi H; Chapman NM; Wen J; Guy C; Long L; Dhungana Y; Rankin S; Pelletier S; Vogel P; Wang H; Peng J; Guan KL; Chi H
    Immunity; 2019 Dec; 51(6):1012-1027.e7. PubMed ID: 31668641
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ubiquitination of Rheb governs growth factor-induced mTORC1 activation.
    Deng L; Chen L; Zhao L; Xu Y; Peng X; Wang X; Ding L; Jin J; Teng H; Wang Y; Pan W; Yu F; Liao L; Li L; Ge X; Wang P
    Cell Res; 2019 Feb; 29(2):136-150. PubMed ID: 30514904
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rag GTPase in amino acid signaling.
    Kim J; Kim E
    Amino Acids; 2016 Apr; 48(4):915-928. PubMed ID: 26781224
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.
    Schweitzer LD; Comb WC; Bar-Peled L; Sabatini DM
    Cell Rep; 2015 Sep; 12(9):1445-55. PubMed ID: 26299971
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Purification and biochemical characterization of the Rag GTPase heterodimer.
    Doxsey DD; Shen K
    Methods Enzymol; 2022; 675():131-158. PubMed ID: 36220268
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MCRS1 binds and couples Rheb to amino acid-dependent mTORC1 activation.
    Fawal MA; Brandt M; Djouder N
    Dev Cell; 2015 Apr; 33(1):67-81. PubMed ID: 25816988
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphatidic acid drives mTORC1 lysosomal translocation in the absence of amino acids.
    Frias MA; Mukhopadhyay S; Lehman E; Walasek A; Utter M; Menon D; Foster DA
    J Biol Chem; 2020 Jan; 295(1):263-274. PubMed ID: 31767684
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes.
    Ögmundsdóttir MH; Heublein S; Kazi S; Reynolds B; Visvalingam SM; Shaw MK; Goberdhan DC
    PLoS One; 2012; 7(5):e36616. PubMed ID: 22574197
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
    Sancak Y; Peterson TR; Shaul YD; Lindquist RA; Thoreen CC; Bar-Peled L; Sabatini DM
    Science; 2008 Jun; 320(5882):1496-501. PubMed ID: 18497260
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.