BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 33163269)

  • 1. Targeting the polycomb repressive complex-2 related proteins with novel combinational strategies for nasopharyngeal carcinoma.
    Zhu J; Li L; Tong J; Hui C; Wong CH; Lo KW; Chan R; Ai QY; Hui EP; Chan AT; To KF; Tao Q; Ma BB
    Am J Cancer Res; 2020; 10(10):3267-3284. PubMed ID: 33163269
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of polycomb repressive complex 2 by targeting EED protects against cisplatin-induced acute kidney injury.
    Yu C; Li T; Li J; Cui B; Liu N; Bayliss G; Zhuang S
    J Cell Mol Med; 2022 Jul; 26(14):4061-4075. PubMed ID: 35734954
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED.
    Qi W; Zhao K; Gu J; Huang Y; Wang Y; Zhang H; Zhang M; Zhang J; Yu Z; Li L; Teng L; Chuai S; Zhang C; Zhao M; Chan H; Chen Z; Fang D; Fei Q; Feng L; Feng L; Gao Y; Ge H; Ge X; Li G; Lingel A; Lin Y; Liu Y; Luo F; Shi M; Wang L; Wang Z; Yu Y; Zeng J; Zeng C; Zhang L; Zhang Q; Zhou S; Oyang C; Atadja P; Li E
    Nat Chem Biol; 2017 Apr; 13(4):381-388. PubMed ID: 28135235
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Wedelolactone disrupts the interaction of EZH2-EED complex and inhibits PRC2-dependent cancer.
    Chen H; Gao S; Li J; Liu D; Sheng C; Yao C; Jiang W; Wu J; Chen S; Huang W
    Oncotarget; 2015 May; 6(15):13049-59. PubMed ID: 25944687
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader.
    Potjewyd F; Turner AW; Beri J; Rectenwald JM; Norris-Drouin JL; Cholensky SH; Margolis DM; Pearce KH; Herring LE; James LI
    Cell Chem Biol; 2020 Jan; 27(1):47-56.e15. PubMed ID: 31831267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhancer of zeste homolog 2 overexpression in nasopharyngeal carcinoma: an independent poor prognosticator that enhances cell growth.
    Hwang CF; Huang HY; Chen CH; Chien CY; Hsu YC; Li CF; Fang FM
    Int J Radiat Oncol Biol Phys; 2012 Feb; 82(2):597-604. PubMed ID: 21300475
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The PRC2 molecule EED is a target of epigenetic therapy for neuroblastoma.
    Shaliman D; Takenobu H; Sugino RP; Ohira M; Kamijo T
    Eur J Cell Biol; 2022; 101(3):151238. PubMed ID: 35636260
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparative methylome analysis in solid tumors reveals aberrant methylation at chromosome 6p in nasopharyngeal carcinoma.
    Dai W; Cheung AK; Ko JM; Cheng Y; Zheng H; Ngan RK; Ng WT; Lee AW; Yau CC; Lee VH; Lung ML
    Cancer Med; 2015 Jul; 4(7):1079-90. PubMed ID: 25924914
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.
    Kong X; Chen L; Jiao L; Jiang X; Lian F; Lu J; Zhu K; Du D; Liu J; Ding H; Zhang N; Shen J; Zheng M; Chen K; Liu X; Jiang H; Luo C
    J Med Chem; 2014 Nov; 57(22):9512-21. PubMed ID: 25369470
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FEZF2, a novel 3p14 tumor suppressor gene, represses oncogene EZH2 and MDM2 expression and is frequently methylated in nasopharyngeal carcinoma.
    Shu XS; Li L; Ji M; Cheng Y; Ying J; Fan Y; Zhong L; Liu X; Tsao SW; Chan AT; Tao Q
    Carcinogenesis; 2013 Sep; 34(9):1984-93. PubMed ID: 23677067
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy.
    Huang Y; Zhang J; Yu Z; Zhang H; Wang Y; Lingel A; Qi W; Gu J; Zhao K; Shultz MD; Wang L; Fu X; Sun Y; Zhang Q; Jiang X; Zhang J; Zhang C; Li L; Zeng J; Feng L; Zhang C; Liu Y; Zhang M; Zhang L; Zhao M; Gao Z; Liu X; Fang D; Guo H; Mi Y; Gabriel T; Dillon MP; Atadja P; Oyang C
    J Med Chem; 2017 Mar; 60(6):2215-2226. PubMed ID: 28092155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells.
    Koppens MA; Bounova G; Gargiulo G; Tanger E; Janssen H; Cornelissen-Steijger P; Blom M; Song JY; Wessels LF; van Lohuizen M
    Gastroenterology; 2016 Oct; 151(4):684-697.e12. PubMed ID: 27342214
    [TBL] [Abstract][Full Text] [Related]  

  • 13. EZH2 regulates the expression of p16 in the nasopharyngeal cancer cells.
    Zhong J; Min L; Huang H; Li L; Li D; Li J; Ma Z; Dai L
    Technol Cancer Res Treat; 2013 Jun; 12(3):269-74. PubMed ID: 23289480
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2.
    Lu J; He ML; Wang L; Chen Y; Liu X; Dong Q; Chen YC; Peng Y; Yao KT; Kung HF; Li XP
    Cancer Res; 2011 Jan; 71(1):225-33. PubMed ID: 21199804
    [TBL] [Abstract][Full Text] [Related]  

  • 15. EZH2 mutations and promoter hypermethylation in childhood acute lymphoblastic leukemia.
    Schäfer V; Ernst J; Rinke J; Winkelmann N; Beck JF; Hochhaus A; Gruhn B; Ernst T
    J Cancer Res Clin Oncol; 2016 Jul; 142(7):1641-50. PubMed ID: 27169594
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The role of the polycomb repressive complex pathway in T and NK cell lymphoma: biological and prognostic implications.
    Kim SH; Yang WI; Min YH; Ko YH; Yoon SO
    Tumour Biol; 2016 Feb; 37(2):2037-47. PubMed ID: 26337274
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Polycomb recruitment at the Class II transactivator gene.
    Boyd NH; Morgan JE; Greer SF
    Mol Immunol; 2015 Oct; 67(2 Pt B):482-91. PubMed ID: 26283540
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of aberrant cell cycle regulation in Epstein-Barr virus-associated nasopharyngeal carcinoma by cDNA microarray and gene set enrichment analysis.
    Zhang W; Zeng Z; Zhou Y; Xiong W; Fan S; Xiao L; Huang D; Li Z; Li D; Wu M; Li X; Shen S; Wang R; Cao L; Tang K; Li G
    Acta Biochim Biophys Sin (Shanghai); 2009 May; 41(5):414-28. PubMed ID: 19430707
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Polycomb Repressive Complex 2 activity reduces trimethylation of H3K27 and affects development in Arabidopsis seedlings.
    Ruta V; Longo C; Boccaccini A; Madia VN; Saccoliti F; Tudino V; Di Santo R; Lorrai R; Dello Ioio R; Sabatini S; Costi R; Costantino P; Vittorioso P
    BMC Plant Biol; 2019 Oct; 19(1):429. PubMed ID: 31619182
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations.
    Zhu K; Du D; Yang R; Tao H; Zhang H
    Chem Pharm Bull (Tokyo); 2020 Jan; 68(1):58-63. PubMed ID: 31685780
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.