BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 33163985)

  • 1. Synthetic Lethal Drug Combinations Targeting Proteasome and Histone Deacetylase Inhibitors in TP53-Mutated Cancers.
    Das S; Deng X; Camphausen K; Shankavaram U
    Arch Cancer Biol Ther; 2020; 1(2):42-47. PubMed ID: 33163985
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SL-BioDP: Multi-Cancer Interactive Tool for Prediction of Synthetic Lethality and Response to Cancer Treatment.
    Deng X; Das S; Valdez K; Camphausen K; Shankavaram U
    Cancers (Basel); 2019 Oct; 11(11):. PubMed ID: 31671773
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FDA-approved drug screen identifies proteasome as a synthetic lethal target in MYC-driven neuroblastoma.
    Wang J; Jiang J; Chen H; Wang L; Guo H; Yang L; Xiao D; Qing G; Liu H
    Oncogene; 2019 Oct; 38(41):6737-6751. PubMed ID: 31406244
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combination of proteasome and HDAC inhibitors for uterine cervical cancer treatment.
    Lin Z; Bazzaro M; Wang MC; Chan KC; Peng S; Roden RB
    Clin Cancer Res; 2009 Jan; 15(2):570-7. PubMed ID: 19147762
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proteasome inhibitors trigger mutations via activation of caspases and CAD, but mutagenesis provoked by the HDAC inhibitors vorinostat and romidepsin is caspase/CAD-independent.
    Miles MA; Harris MA; Hawkins CJ
    Apoptosis; 2019 Jun; 24(5-6):404-413. PubMed ID: 30997620
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ranking novel cancer driving synthetic lethal gene pairs using TCGA data.
    Ye H; Zhang X; Chen Y; Liu Q; Wei J
    Oncotarget; 2016 Aug; 7(34):55352-55367. PubMed ID: 27438146
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer.
    Alzoubi S; Brody L; Rahman S; Mahul-Mellier AL; Mercado N; Ito K; El-Bahrawy M; Silver A; Boobis A; Bell JD; Hajji N
    Oncotarget; 2016 Jul; 7(28):44505-44521. PubMed ID: 27283986
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Combination of vorinostat and flavopiridol is selectively cytotoxic to multidrug-resistant neuroblastoma cell lines with mutant TP53.
    Huang JM; Sheard MA; Ji L; Sposto R; Keshelava N
    Mol Cancer Ther; 2010 Dec; 9(12):3289-301. PubMed ID: 21159612
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combination of proteasome and class I HDAC inhibitors induces apoptosis of NPC cells through an HDAC6-independent ER stress-induced mechanism.
    Hui KF; Chiang AK
    Int J Cancer; 2014 Dec; 135(12):2950-61. PubMed ID: 24771510
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Carfilzomib and oprozomib synergize with histone deacetylase inhibitors in head and neck squamous cell carcinoma models of acquired resistance to proteasome inhibitors.
    Zang Y; Kirk CJ; Johnson DE
    Cancer Biol Ther; 2014 Sep; 15(9):1142-52. PubMed ID: 24915039
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors.
    Pei XY; Dai Y; Grant S
    Clin Cancer Res; 2004 Jun; 10(11):3839-52. PubMed ID: 15173093
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Changes in histone deacetylase (HDAC) expression patterns and activity of HDAC inhibitors in urothelial cancers.
    Niegisch G; Knievel J; Koch A; Hader C; Fischer U; Albers P; Schulz WA
    Urol Oncol; 2013 Nov; 31(8):1770-9. PubMed ID: 22944197
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The class-I HDAC inhibitor MGCD0103 induces apoptosis in Hodgkin lymphoma cell lines and synergizes with proteasome inhibitors by an HDAC6-independent mechanism.
    Buglio D; Mamidipudi V; Khaskhely NM; Brady H; Heise C; Besterman J; Martell RE; MacBeth K; Younes A
    Br J Haematol; 2010 Nov; 151(4):387-96. PubMed ID: 20880107
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo.
    Dasmahapatra G; Lembersky D; Kramer L; Fisher RI; Friedberg J; Dent P; Grant S
    Blood; 2010 Jun; 115(22):4478-87. PubMed ID: 20233973
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases.
    Kikuchi J; Yamada S; Koyama D; Wada T; Nobuyoshi M; Izumi T; Akutsu M; Kano Y; Furukawa Y
    J Biol Chem; 2013 Aug; 288(35):25593-25602. PubMed ID: 23878197
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of histone deacetylase (HDAC) family members in bortezomib-refractory multiple myeloma and modulation by panobinostat.
    Cheng T; Kiser K; Grasse L; Iles L; Bartholomeusz G; Samaniego F; Orlowski RZ; Chandra J
    Cancer Drug Resist; 2021; 4(4):888-902. PubMed ID: 34888496
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HDAC inhibitor L-carnitine and proteasome inhibitor bortezomib synergistically exert anti-tumor activity in vitro and in vivo.
    Huang H; Liu N; Yang C; Liao S; Guo H; Zhao K; Li X; Liu S; Guan L; Liu C; Xu L; Zhang C; Song W; Li B; Tang P; Dou QP; Liu J
    PLoS One; 2012; 7(12):e52576. PubMed ID: 23285100
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer.
    Srihari S; Singla J; Wong L; Ragan MA
    Biol Direct; 2015 Oct; 10():57. PubMed ID: 26427375
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synergistic induction of apoptosis and chemosensitization of human colorectal cancer cells by histone deacetylase inhibitor, scriptaid, and proteasome inhibitors: potential mechanisms of action.
    Abaza MS; Bahman AM; Al-Attiyah RJ; Kollamparambil AM
    Tumour Biol; 2012 Dec; 33(6):1951-72. PubMed ID: 23011889
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells.
    Zhang B; Lyu J; Yang EJ; Liu Y; Wu C; Pardeshi L; Tan K; Chen Q; Xu X; Deng CX; Shim JS
    Acta Pharm Sin B; 2020 Apr; 10(4):615-627. PubMed ID: 32322466
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.