BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 33164337)

  • 1. Penetration, distribution, and elimination of remofuscin/soraprazan in Stargardt mouse eyes following a single intravitreal injection using pharmacokinetics and transmission electron microscopic autoradiography: Implication for the local treatment of Stargardt's disease and dry age-related macular degeneration.
    Julien-Schraermeyer S; Illing B; Tschulakow A; Taubitz T; Guezguez J; Burnet M; Schraermeyer U
    Pharmacol Res Perspect; 2020 Dec; 8(6):e00683. PubMed ID: 33164337
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Removal of RPE lipofuscin results in rescue from retinal degeneration in a mouse model of advanced Stargardt disease: Role of reactive oxygen species.
    Fang Y; Taubitz T; Tschulakow AV; Heiduschka P; Szewczyk G; Burnet M; Peters T; Biesemeier A; Sarna T; Schraermeyer U; Julien-Schraermeyer S
    Free Radic Biol Med; 2022 Mar; 182():132-149. PubMed ID: 35219849
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration.
    Radu RA; Mata NL; Nusinowitz S; Liu X; Sieving PA; Travis GH
    Proc Natl Acad Sci U S A; 2003 Apr; 100(8):4742-7. PubMed ID: 12671074
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lipofuscin can be eliminated from the retinal pigment epithelium of monkeys.
    Julien S; Schraermeyer U
    Neurobiol Aging; 2012 Oct; 33(10):2390-7. PubMed ID: 22244091
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy.
    Conley SM; Cai X; Makkia R; Wu Y; Sparrow JR; Naash MI
    Biochim Biophys Acta; 2012 Jul; 1822(7):1169-79. PubMed ID: 22033104
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Isotretinoin treatment inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration.
    Radu RA; Mata NL; Nusinowitz S; Liu X; Travis GH
    Novartis Found Symp; 2004; 255():51-63; discussion 63-7, 177-8. PubMed ID: 14750596
    [TBL] [Abstract][Full Text] [Related]  

  • 7. C20-D3-vitamin A slows lipofuscin accumulation and electrophysiological retinal degeneration in a mouse model of Stargardt disease.
    Ma L; Kaufman Y; Zhang J; Washington I
    J Biol Chem; 2011 Mar; 286(10):7966-7974. PubMed ID: 21156790
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Iron accumulation in Bruch's membrane and melanosomes of donor eyes with age-related macular degeneration.
    Biesemeier A; Yoeruek E; Eibl O; Schraermeyer U
    Exp Eye Res; 2015 Aug; 137():39-49. PubMed ID: 26026877
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fundus autofluorescence in the Abca4(-/-) mouse model of Stargardt disease--correlation with accumulation of A2E, retinal function, and histology.
    Charbel Issa P; Barnard AR; Singh MS; Carter E; Jiang Z; Radu RA; Schraermeyer U; MacLaren RE
    Invest Ophthalmol Vis Sci; 2013 Aug; 54(8):5602-12. PubMed ID: 23761084
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD).
    Ramkumar HL; Zhang J; Chan CC
    Prog Retin Eye Res; 2010 May; 29(3):169-90. PubMed ID: 20206286
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dry age-related macular degeneration like pathology in aged 5XFAD mice: Ultrastructure and microarray analysis.
    Park SW; Im S; Jun HO; Lee K; Park YJ; Kim JH; Park WJ; Lee YH; Kim JH
    Oncotarget; 2017 Jun; 8(25):40006-40018. PubMed ID: 28467791
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration.
    Mata NL; Tzekov RT; Liu X; Weng J; Birch DG; Travis GH
    Invest Ophthalmol Vis Sci; 2001 Jul; 42(8):1685-90. PubMed ID: 11431429
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Retina and RPE lipid profile changes linked with ABCA4 associated Stargardt's maculopathy.
    Farnoodian M; Bose D; Barone F; Nelson LM; Boyle M; Jun B; Do K; Gordon W; Guerin MK; Perera R; Ji JX; Cogliati T; Sharma R; Brooks BP; Bazan NG; Bharti K
    Pharmacol Ther; 2023 Sep; 249():108482. PubMed ID: 37385300
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Recombinant Manganese Peroxidase Reduces A2E Burden in Age-Related and Stargardt's Macular Degeneration Models.
    Moody KJ; Tinklepaugh J; Obert E; Grohn K; DeRosa JR; Lumen E; Moyer BS; Campbell S; Wolfe AJ; Sleeper MB; Bianchi AH; Fisher C; Applegate J; Leary E; LeClair N; Wortel D; Doyle RP; Rohrer B; Blanden AR
    Rejuvenation Res; 2018 Dec; 21(6):560-571. PubMed ID: 30516450
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease.
    Fontaine V; Monteiro E; FourniƩ M; Brazhnikova E; Boumedine T; Vidal C; Balducci C; Guibout L; Latil M; Dilda PJ; Veillet S; Sahel JA; Lafont R; Camelo S
    Aging (Albany NY); 2020 Apr; 12(7):6151-6171. PubMed ID: 32255762
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enhanced accumulation of A2E in individuals homozygous or heterozygous for mutations in BEST1 (VMD2).
    Bakall B; Radu RA; Stanton JB; Burke JM; McKay BS; Wadelius C; Mullins RF; Stone EM; Travis GH; Marmorstein AD
    Exp Eye Res; 2007 Jul; 85(1):34-43. PubMed ID: 17477921
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ultrastructural alterations in the retinal pigment epithelium and photoreceptors of a Stargardt patient and three Stargardt mouse models: indication for the central role of RPE melanin in oxidative stress.
    Taubitz T; Tschulakow AV; Tikhonovich M; Illing B; Fang Y; Biesemeier A; Julien-Schraermeyer S; Schraermeyer U
    PeerJ; 2018; 6():e5215. PubMed ID: 30038866
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A non-retinoid antagonist of retinol-binding protein 4 rescues phenotype in a model of Stargardt disease without inhibiting the visual cycle.
    Racz B; Varadi A; Kong J; Allikmets R; Pearson PG; Johnson G; Cioffi CL; Petrukhin K
    J Biol Chem; 2018 Jul; 293(29):11574-11588. PubMed ID: 29871924
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chemiexcitation and melanin in photoreceptor disc turnover and prevention of macular degeneration.
    Lyu Y; Tschulakow AV; Wang K; Brash DE; Schraermeyer U
    Proc Natl Acad Sci U S A; 2023 May; 120(20):e2216935120. PubMed ID: 37155898
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stem Cell-Based Therapy for Diseases of the Retinal Pigment Epithelium: From Bench to Bedside.
    Sachdeva MM; Eliott D
    Semin Ophthalmol; 2016; 31(1-2):25-9. PubMed ID: 26959126
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.