BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

383 related articles for article (PubMed ID: 33168090)

  • 1. Soluble and insoluble dipeptide repeat protein measurements in C9orf72-frontotemporal dementia brains show regional differential solubility and correlation of poly-GR with clinical severity.
    Quaegebeur A; Glaria I; Lashley T; Isaacs AM
    Acta Neuropathol Commun; 2020 Nov; 8(1):184. PubMed ID: 33168090
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers.
    Mackenzie IR; Frick P; Grässer FA; Gendron TF; Petrucelli L; Cashman NR; Edbauer D; Kremmer E; Prudlo J; Troost D; Neumann M
    Acta Neuropathol; 2015 Dec; 130(6):845-61. PubMed ID: 26374446
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.
    Saberi S; Stauffer JE; Jiang J; Garcia SD; Taylor AE; Schulte D; Ohkubo T; Schloffman CL; Maldonado M; Baughn M; Rodriguez MJ; Pizzo D; Cleveland D; Ravits J
    Acta Neuropathol; 2018 Mar; 135(3):459-474. PubMed ID: 29196813
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins.
    Darling AL; Breydo L; Rivas EG; Gebru NT; Zheng D; Baker JD; Blair LJ; Dickey CA; Koren J; Uversky VN
    Int J Biol Macromol; 2019 Apr; 127():136-145. PubMed ID: 30639592
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration.
    Gomez-Deza J; Lee YB; Troakes C; Nolan M; Al-Sarraj S; Gallo JM; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():38. PubMed ID: 26108573
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD.
    Krishnan G; Raitcheva D; Bartlett D; Prudencio M; McKenna-Yasek DM; Douthwright C; Oskarsson BE; Ladha S; King OD; Barmada SJ; Miller TM; Bowser R; Watts JK; Petrucelli L; Brown RH; Kankel MW; Gao FB
    Nat Commun; 2022 May; 13(1):2799. PubMed ID: 35589711
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Translation of dipeptide repeat proteins in
    Sonobe Y; Lee S; Krishnan G; Gu Y; Kwon DY; Gao FB; Roos RP; Kratsios P
    Elife; 2023 Sep; 12():. PubMed ID: 37675986
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Poly-GR dipeptide repeat polymers correlate with neurodegeneration and Clinicopathological subtypes in C9ORF72-related brain disease.
    Sakae N; Bieniek KF; Zhang YJ; Ross K; Gendron TF; Murray ME; Rademakers R; Petrucelli L; Dickson DW
    Acta Neuropathol Commun; 2018 Jul; 6(1):63. PubMed ID: 30029693
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing.
    Schludi MH; May S; Grässer FA; Rentzsch K; Kremmer E; Küpper C; Klopstock T; ; ; Arzberger T; Edbauer D
    Acta Neuropathol; 2015 Oct; 130(4):537-55. PubMed ID: 26085200
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dipeptide repeat proteins inhibit homology-directed DNA double strand break repair in C9ORF72 ALS/FTD.
    Andrade NS; Ramic M; Esanov R; Liu W; Rybin MJ; Gaidosh G; Abdallah A; Del'Olio S; Huff TC; Chee NT; Anatha S; Gendron TF; Wahlestedt C; Zhang Y; Benatar M; Mueller C; Zeier Z
    Mol Neurodegener; 2020 Feb; 15(1):13. PubMed ID: 32093728
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases.
    Dedeene L; Van Schoor E; Vandenberghe R; Van Damme P; Poesen K; Thal DR
    Acta Neuropathol Commun; 2019 Dec; 7(1):189. PubMed ID: 31791419
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36.
    McEachin ZT; Gendron TF; Raj N; García-Murias M; Banerjee A; Purcell RH; Ward PJ; Todd TW; Merritt-Garza ME; Jansen-West K; Hales CM; García-Sobrino T; Quintáns B; Holler CJ; Taylor G; San Millán B; Teijeira S; Yamashita T; Ohkubo R; Boulis NM; Xu C; Wen Z; Streichenberger N; ; Fogel BL; Kukar T; Abe K; Dickson DW; Arias M; Glass JD; Jiang J; Tansey MG; Sobrido MJ; Petrucelli L; Rossoll W; Bassell GJ
    Neuron; 2020 Jul; 107(2):292-305.e6. PubMed ID: 32375063
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations.
    Mackenzie IR; Arzberger T; Kremmer E; Troost D; Lorenzl S; Mori K; Weng SM; Haass C; Kretzschmar HA; Edbauer D; Neumann M
    Acta Neuropathol; 2013 Dec; 126(6):859-79. PubMed ID: 24096617
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72.
    Davidson YS; Barker H; Robinson AC; Thompson JC; Harris J; Troakes C; Smith B; Al-Saraj S; Shaw C; Rollinson S; Masuda-Suzukake M; Hasegawa M; Pickering-Brown S; Snowden JS; Mann DM
    Acta Neuropathol Commun; 2014 Jun; 2():70. PubMed ID: 24950788
    [TBL] [Abstract][Full Text] [Related]  

  • 15. C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.
    Lee YB; Baskaran P; Gomez-Deza J; Chen HJ; Nishimura AL; Smith BN; Troakes C; Adachi Y; Stepto A; Petrucelli L; Gallo JM; Hirth F; Rogelj B; Guthrie S; Shaw CE
    Hum Mol Genet; 2017 Dec; 26(24):4765-4777. PubMed ID: 28973350
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phase Separation of Toxic Dipeptide Repeat Proteins Related to C9orf72 ALS/FTD.
    Jafarinia H; van der Giessen E; Onck PR
    Biophys J; 2020 Aug; 119(4):843-851. PubMed ID: 32730793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.
    Yin S; Lopez-Gonzalez R; Kunz RC; Gangopadhyay J; Borufka C; Gygi SP; Gao FB; Reed R
    Cell Rep; 2017 Jun; 19(11):2244-2256. PubMed ID: 28614712
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients.
    Mordes DA; Prudencio M; Goodman LD; Klim JR; Moccia R; Limone F; Pietilainen O; Chowdhary K; Dickson DW; Rademakers R; Bonini NM; Petrucelli L; Eggan K
    Acta Neuropathol Commun; 2018 Jul; 6(1):55. PubMed ID: 29973287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proximity proteomics of C9orf72 dipeptide repeat proteins identifies molecular chaperones as modifiers of poly-GA aggregation.
    Liu F; Morderer D; Wren MC; Vettleson-Trutza SA; Wang Y; Rabichow BE; Salemi MR; Phinney BS; Oskarsson B; Dickson DW; Rossoll W
    Acta Neuropathol Commun; 2022 Feb; 10(1):22. PubMed ID: 35164882
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis.
    Wang R; Xu X; Hao Z; Zhang S; Wu D; Sun H; Mu C; Ren H; Wang G
    Neurosci Bull; 2019 Oct; 35(5):889-900. PubMed ID: 31148094
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.