BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 33169019)

  • 1. Mechanism of auto-inhibition and activation of Mec1
    Tannous EA; Yates LA; Zhang X; Burgers PM
    Nat Struct Mol Biol; 2021 Jan; 28(1):50-61. PubMed ID: 33169019
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ddc2ATRIP promotes Mec1ATR activation at RPA-ssDNA tracts.
    Biswas H; Goto G; Wang W; Sung P; Sugimoto K
    PLoS Genet; 2019 Aug; 15(8):e1008294. PubMed ID: 31369547
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ddc2 mediates Mec1 activation through a Ddc1- or Dpb11-independent mechanism.
    Bandhu A; Kang J; Fukunaga K; Goto G; Sugimoto K
    PLoS Genet; 2014 Feb; 10(2):e1004136. PubMed ID: 24586187
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mec1
    Memisoglu G; Lanz MC; Eapen VV; Jordan JM; Lee K; Smolka MB; Haber JE
    Cell Rep; 2019 Jul; 28(4):1090-1102.e3. PubMed ID: 31340146
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dpb11 activates the Mec1-Ddc2 complex.
    Mordes DA; Nam EA; Cortez D
    Proc Natl Acad Sci U S A; 2008 Dec; 105(48):18730-4. PubMed ID: 19028869
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.
    Deshpande I; Seeber A; Shimada K; Keusch JJ; Gut H; Gasser SM
    Mol Cell; 2017 Oct; 68(2):431-445.e5. PubMed ID: 29033322
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling.
    Lanz MC; Oberly S; Sanford EJ; Sharma S; Chabes A; Smolka MB
    Genes Dev; 2018 Jun; 32(11-12):822-835. PubMed ID: 29899143
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.
    Hustedt N; Seeber A; Sack R; Tsai-Pflugfelder M; Bhullar B; Vlaming H; van Leeuwen F; Guénolé A; van Attikum H; Srivas R; Ideker T; Shimada K; Gasser SM
    Mol Cell; 2015 Jan; 57(2):273-89. PubMed ID: 25533186
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A DNA damage-induced phosphorylation circuit enhances Mec1
    Yates LA; Tannous EA; Morgan RM; Burgers PM; Zhang X
    Proc Natl Acad Sci U S A; 2023 Apr; 120(14):e2300150120. PubMed ID: 36996117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 3.9 Å structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP.
    Wang X; Ran T; Zhang X; Xin J; Zhang Z; Wu T; Wang W; Cai G
    Science; 2017 Dec; 358(6367):1206-1209. PubMed ID: 29191911
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preparation of endogenous TopBP1/Dpb11 and effect on central checkpoint kinase Mec1- Ddc2 (human ATR-ATRIP homolog).
    Wu T; Zhang Z; Wang X
    Biochem Biophys Res Commun; 2019 Sep; 517(2):291-296. PubMed ID: 31349966
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphoregulation of the checkpoint kinase Mec1
    Yates LA; Zhang X
    DNA Repair (Amst); 2023 Sep; 129():103543. PubMed ID: 37480741
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Yet another job for Dna2: Checkpoint activation.
    Wanrooij PH; Burgers PM
    DNA Repair (Amst); 2015 Aug; 32():17-23. PubMed ID: 25956863
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of ATR-related protein kinase upon DNA damage recognition.
    Ma M; Rodriguez A; Sugimoto K
    Curr Genet; 2020 Apr; 66(2):327-333. PubMed ID: 31624858
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ATR/Mec1: coordinating fork stability and repair.
    Friedel AM; Pike BL; Gasser SM
    Curr Opin Cell Biol; 2009 Apr; 21(2):237-44. PubMed ID: 19230642
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The unstructured C-terminal tail of yeast Dpb11 (human TopBP1) protein is dispensable for DNA replication and the S phase checkpoint but required for the G2/M checkpoint.
    Navadgi-Patil VM; Kumar S; Burgers PM
    J Biol Chem; 2011 Nov; 286(47):40999-1007. PubMed ID: 21956112
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeast.
    Dubrana K; van Attikum H; Hediger F; Gasser SM
    J Cell Sci; 2007 Dec; 120(Pt 23):4209-20. PubMed ID: 18003698
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response.
    Baldo V; Testoni V; Lucchini G; Longhese MP
    Mol Cell Biol; 2008 Jan; 28(1):358-75. PubMed ID: 17954565
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphoproteomics reveals a distinctive Mec1/ATR signaling response upon DNA end hyper-resection.
    Sanford EJ; Comstock WJ; Faça VM; Vega SC; Gnügge R; Symington LS; Smolka MB
    EMBO J; 2021 May; 40(10):e104566. PubMed ID: 33764556
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Colocalization of Mec1 and Mrc1 is sufficient for Rad53 phosphorylation in vivo.
    Berens TJ; Toczyski DP
    Mol Biol Cell; 2012 Mar; 23(6):1058-67. PubMed ID: 22298423
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.