632 related articles for article (PubMed ID: 33172210)
1. Stress-Specific Spatiotemporal Responses of RNA-Binding Proteins in Human Stem-Cell-Derived Motor Neurons.
Harley J; Patani R
Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33172210
[TBL] [Abstract][Full Text] [Related]
2. RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations.
Daigle JG; Lanson NA; Smith RB; Casci I; Maltare A; Monaghan J; Nichols CD; Kryndushkin D; Shewmaker F; Pandey UB
Hum Mol Genet; 2013 Mar; 22(6):1193-205. PubMed ID: 23257289
[TBL] [Abstract][Full Text] [Related]
3. The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for
Tischbein M; Baron DM; Lin YC; Gall KV; Landers JE; Fallini C; Bosco DA
J Biol Chem; 2019 Jun; 294(26):10194-10210. PubMed ID: 31092554
[TBL] [Abstract][Full Text] [Related]
4. TDP-43 and FUS en route from the nucleus to the cytoplasm.
Ederle H; Dormann D
FEBS Lett; 2017 Jun; 591(11):1489-1507. PubMed ID: 28380257
[TBL] [Abstract][Full Text] [Related]
5. Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis.
Tyzack GE; Luisier R; Taha DM; Neeves J; Modic M; Mitchell JS; Meyer I; Greensmith L; Newcombe J; Ule J; Luscombe NM; Patani R
Brain; 2019 Sep; 142(9):2572-2580. PubMed ID: 31368485
[TBL] [Abstract][Full Text] [Related]
6. FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy.
Marrone L; Drexler HCA; Wang J; Tripathi P; Distler T; Heisterkamp P; Anderson EN; Kour S; Moraiti A; Maharana S; Bhatnagar R; Belgard TG; Tripathy V; Kalmbach N; Hosseinzadeh Z; Crippa V; Abo-Rady M; Wegner F; Poletti A; Troost D; Aronica E; Busskamp V; Weis J; Pandey UB; Hyman AA; Alberti S; Goswami A; Sterneckert J
Acta Neuropathol; 2019 Jul; 138(1):67-84. PubMed ID: 30937520
[TBL] [Abstract][Full Text] [Related]
7. Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis.
Smethurst P; Risse E; Tyzack GE; Mitchell JS; Taha DM; Chen YR; Newcombe J; Collinge J; Sidle K; Patani R
Brain; 2020 Feb; 143(2):430-440. PubMed ID: 32040555
[TBL] [Abstract][Full Text] [Related]
8. Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis.
De Santis R; Alfano V; de Turris V; Colantoni A; Santini L; Garone MG; Antonacci G; Peruzzi G; Sudria-Lopez E; Wyler E; Anink JJ; Aronica E; Landthaler M; Pasterkamp RJ; Bozzoni I; Rosa A
Cell Rep; 2019 Jun; 27(13):3818-3831.e5. PubMed ID: 31242416
[TBL] [Abstract][Full Text] [Related]
9. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD.
Fang MY; Markmiller S; Vu AQ; Javaherian A; Dowdle WE; Jolivet P; Bushway PJ; Castello NA; Baral A; Chan MY; Linsley JW; Linsley D; Mercola M; Finkbeiner S; Lecuyer E; Lewcock JW; Yeo GW
Neuron; 2019 Sep; 103(5):802-819.e11. PubMed ID: 31272829
[TBL] [Abstract][Full Text] [Related]
10. TDP-43 and FUS mislocalization in VCP mutant motor neurons is reversed by pharmacological inhibition of the VCP D2 ATPase domain.
Harley J; Hagemann C; Serio A; Patani R
Brain Commun; 2021; 3(3):fcab166. PubMed ID: 34396115
[TBL] [Abstract][Full Text] [Related]
11. Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress.
Markmiller S; Sathe S; Server KL; Nguyen TB; Fulzele A; Cody N; Javaherian A; Broski S; Finkbeiner S; Bennett EJ; Lécuyer E; Yeo GW
Cell Rep; 2021 Sep; 36(10):109685. PubMed ID: 34496257
[TBL] [Abstract][Full Text] [Related]
12. FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration.
Szewczyk B; Günther R; Japtok J; Frech MJ; Naumann M; Lee HO; Hermann A
Cell Rep; 2023 Feb; 42(2):112025. PubMed ID: 36696267
[TBL] [Abstract][Full Text] [Related]
13. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH
Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035
[TBL] [Abstract][Full Text] [Related]
14. Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition.
Ziff OJ; Harley J; Wang Y; Neeves J; Tyzack G; Ibrahim F; Skehel M; Chakrabarti AM; Kelly G; Patani R
Neuron; 2023 Oct; 111(19):3011-3027.e7. PubMed ID: 37480846
[TBL] [Abstract][Full Text] [Related]
15. Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations.
Finelli MJ; Liu KX; Wu Y; Oliver PL; Davies KE
Hum Mol Genet; 2015 Jun; 24(12):3529-44. PubMed ID: 25792726
[TBL] [Abstract][Full Text] [Related]
16. Cytoplasmic aggregation of mutant FUS causes multistep RNA splicing perturbations in the course of motor neuron pathology.
Rezvykh AP; Ustyugov AA; Chaprov KD; Teterina EV; Nebogatikov VO; Spasskaya DS; Evgen'ev MB; Morozov AV; Funikov SY
Nucleic Acids Res; 2023 Jun; 51(11):5810-5830. PubMed ID: 37115004
[TBL] [Abstract][Full Text] [Related]
17. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.
Naumann M; Pal A; Goswami A; Lojewski X; Japtok J; Vehlow A; Naujock M; Günther R; Jin M; Stanslowsky N; Reinhardt P; Sterneckert J; Frickenhaus M; Pan-Montojo F; Storkebaum E; Poser I; Freischmidt A; Weishaupt JH; Holzmann K; Troost D; Ludolph AC; Boeckers TM; Liebau S; Petri S; Cordes N; Hyman AA; Wegner F; Grill SW; Weis J; Storch A; Hermann A
Nat Commun; 2018 Jan; 9(1):335. PubMed ID: 29362359
[TBL] [Abstract][Full Text] [Related]
18. The fused in sarcoma protein forms cytoplasmic aggregates in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral sclerosis carrying the FUS-P525L mutation.
Liu X; Chen J; Liu W; Li X; Chen Q; Liu T; Gao S; Deng M
Neurogenetics; 2015 Jul; 16(3):223-31. PubMed ID: 25912081
[TBL] [Abstract][Full Text] [Related]
19. FUS is lost from nuclei and gained in neurites of motor neurons in a human stem cell model of VCP-related ALS.
Harley J; Hagemann C; Serio A; Patani R
Brain; 2020 Dec; 143(12):e103. PubMed ID: 33253377
[No Abstract] [Full Text] [Related]
20. Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.
Lu L; Zheng L; Si Y; Luo W; Dujardin G; Kwan T; Potochick NR; Thompson SR; Schneider DA; King PH
J Biol Chem; 2014 Nov; 289(46):31792-31804. PubMed ID: 25239623
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]