BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 33172974)

  • 1. 5-Azacytidine Transiently Restores Dysregulated Erythroid Differentiation Gene Expression in TET2-Deficient Erythroleukemia Cells.
    Reilly BM; Luger T; Park S; Lio CJ; González-Avalos E; Wheeler EC; Lee M; Williamson L; Tanaka T; Diep D; Zhang K; Huang Y; Rao A; Bejar R
    Mol Cancer Res; 2021 Mar; 19(3):451-464. PubMed ID: 33172974
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells.
    Putiri EL; Tiedemann RL; Thompson JJ; Liu C; Ho T; Choi JH; Robertson KD
    Genome Biol; 2014 Jun; 15(6):R81. PubMed ID: 24958354
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation.
    Ruiz MA; Rivers A; Ibanez V; Vaitkus K; Mahmud N; DeSimone J; Lavelle D
    Epigenetics; 2015; 10(5):397-407. PubMed ID: 25932923
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Cell Type-Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia.
    Nakauchi Y; Azizi A; Thomas D; Corces MR; Reinisch A; Sharma R; Cruz Hernandez D; Köhnke T; Karigane D; Fan A; Martinez-Krams D; Stafford M; Kaur S; Dutta R; Phan P; Ediriwickrema A; McCarthy E; Ning Y; Phillips T; Ellison CK; Guler GD; Bergamaschi A; Ku CJ; Levy S; Majeti R
    Blood Cancer Discov; 2022 Jul; 3(4):346-367. PubMed ID: 35532363
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.
    Montagner S; Leoni C; Emming S; Della Chiara G; Balestrieri C; Barozzi I; Piccolo V; Togher S; Ko M; Rao A; Natoli G; Monticelli S
    Cell Rep; 2016 May; 15(7):1566-1579. PubMed ID: 27160912
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TET2 as a tumor suppressor and therapeutic target in T-cell acute lymphoblastic leukemia.
    Bensberg M; Rundquist O; Selimović A; Lagerwall C; Benson M; Gustafsson M; Vogt H; Lentini A; Nestor CE
    Proc Natl Acad Sci U S A; 2021 Aug; 118(34):. PubMed ID: 34413196
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
    Rampal R; Alkalin A; Madzo J; Vasanthakumar A; Pronier E; Patel J; Li Y; Ahn J; Abdel-Wahab O; Shih A; Lu C; Ward PS; Tsai JJ; Hricik T; Tosello V; Tallman JE; Zhao X; Daniels D; Dai Q; Ciminio L; Aifantis I; He C; Fuks F; Tallman MS; Ferrando A; Nimer S; Paietta E; Thompson CB; Licht JD; Mason CE; Godley LA; Melnick A; Figueroa ME; Levine RL
    Cell Rep; 2014 Dec; 9(5):1841-1855. PubMed ID: 25482556
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA methylcytosine dioxygenase ten-eleven translocation 2 enhances lipopolysaccharide-induced cytokine expression in human dental pulp cells by regulating MyD88 hydroxymethylation.
    Wang X; Feng Z; Li Q; Yi B; Xu Q
    Cell Tissue Res; 2018 Aug; 373(2):477-485. PubMed ID: 29654353
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TET proteins and 5-methylcytosine oxidation in hematological cancers.
    Ko M; An J; Pastor WA; Koralov SB; Rajewsky K; Rao A
    Immunol Rev; 2015 Jan; 263(1):6-21. PubMed ID: 25510268
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions.
    Broome R; Chernukhin I; Jamieson S; Kishore K; Papachristou EK; Mao SQ; Tejedo CG; Mahtey A; Theodorou V; Groen AJ; D'Santos C; Balasubramanian S; Farcas AM; Siersbæk R; Carroll JS
    Cell Rep; 2021 Feb; 34(8):108776. PubMed ID: 33626359
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinct roles for TET family proteins in regulating human erythropoiesis.
    Yan H; Wang Y; Qu X; Li J; Hale J; Huang Y; An C; Papoin J; Guo X; Chen L; Kang Q; Li W; Schulz VP; Gallagher PG; Hillyer CD; Mohandas N; An X
    Blood; 2017 Apr; 129(14):2002-2012. PubMed ID: 28167661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sox2 induces glioblastoma cell stemness and tumor propagation by repressing TET2 and deregulating 5hmC and 5mC DNA modifications.
    Lopez-Bertoni H; Johnson A; Rui Y; Lal B; Sall S; Malloy M; Coulter JB; Lugo-Fagundo M; Shudir S; Khela H; Caputo C; Green JJ; Laterra J
    Signal Transduct Target Ther; 2022 Feb; 7(1):37. PubMed ID: 35136034
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.
    Ficz G; Branco MR; Seisenberger S; Santos F; Krueger F; Hore TA; Marques CJ; Andrews S; Reik W
    Nature; 2011 May; 473(7347):398-402. PubMed ID: 21460836
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tet2-mediated DNA demethylation regulates the proliferation and apoptosis of human leukemia K562 cells.
    Qiao Y; Zhou Y; Yang H; He Z; Fan A
    Cell Mol Biol (Noisy-le-grand); 2023 Mar; 69(3):23-27. PubMed ID: 37300692
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation.
    Hon GC; Song CX; Du T; Jin F; Selvaraj S; Lee AY; Yen CA; Ye Z; Mao SQ; Wang BA; Kuan S; Edsall LE; Zhao BS; Xu GL; He C; Ren B
    Mol Cell; 2014 Oct; 56(2):286-297. PubMed ID: 25263596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma.
    Sajadian SO; Ehnert S; Vakilian H; Koutsouraki E; Damm G; Seehofer D; Thasler W; Dooley S; Baharvand H; Sipos B; Nussler AK
    Clin Epigenetics; 2015; 7(1):98. PubMed ID: 26366235
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy)methylation and gene expression to maintain a neoplastic phenotype in T-ALL.
    Poole CJ; Lodh A; Choi JH; van Riggelen J
    Epigenetics Chromatin; 2019 Jul; 12(1):41. PubMed ID: 31266538
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing.
    Gjini E; Mansour MR; Sander JD; Moritz N; Nguyen AT; Kesarsing M; Gans E; He S; Chen S; Ko M; Kuang YY; Yang S; Zhou Y; Rodig S; Zon LI; Joung JK; Rao A; Look AT
    Mol Cell Biol; 2015 Mar; 35(5):789-804. PubMed ID: 25512612
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
    Ko M; Huang Y; Jankowska AM; Pape UJ; Tahiliani M; Bandukwala HS; An J; Lamperti ED; Koh KP; Ganetzky R; Liu XS; Aravind L; Agarwal S; Maciejewski JP; Rao A
    Nature; 2010 Dec; 468(7325):839-43. PubMed ID: 21057493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and inflammation in Sjögren's syndrome patients.
    Lagos C; Carvajal P; Castro I; Jara D; González S; Aguilera S; Barrera MJ; Quest AFG; Bahamondes V; Molina C; Urzúa U; Hermoso MA; Leyton C; González MJ
    Clin Immunol; 2018 Nov; 196():85-96. PubMed ID: 29894742
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.