BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 33177163)

  • 1. ATF4 activation promotes hepatic mitochondrial dysfunction by repressing NRF1-TFAM signalling in alcoholic steatohepatitis.
    Hao L; Zhong W; Dong H; Guo W; Sun X; Zhang W; Yue R; Li T; Griffiths A; Ahmadi AR; Sun Z; Song Z; Zhou Z
    Gut; 2021 Oct; 70(10):1933-1945. PubMed ID: 33177163
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Liver-specific Gene Inactivation of the Transcription Factor ATF4 Alleviates Alcoholic Liver Steatosis in Mice.
    Li K; Xiao Y; Yu J; Xia T; Liu B; Guo Y; Deng J; Chen S; Wang C; Guo F
    J Biol Chem; 2016 Aug; 291(35):18536-46. PubMed ID: 27405764
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans.
    Xu MJ; Cai Y; Wang H; Altamirano J; Chang B; Bertola A; Odena G; Lu J; Tanaka N; Matsusue K; Matsubara T; Mukhopadhyay P; Kimura S; Pacher P; Gonzalez FJ; Bataller R; Gao B
    Gastroenterology; 2015 Oct; 149(4):1030-41.e6. PubMed ID: 26099526
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rice Bran Phenolic Extract Confers Protective Effects against Alcoholic Liver Disease in Mice by Alleviating Mitochondrial Dysfunction via the PGC-1α-TFAM Pathway Mediated by microRNA-494-3p.
    Xiao J; Wu C; He Y; Guo M; Peng Z; Liu Y; Liu L; Dong L; Guo Z; Zhang R; Zhang M
    J Agric Food Chem; 2020 Nov; 68(44):12284-12294. PubMed ID: 33094608
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis.
    He F; Zhang P; Liu J; Wang R; Kaufman RJ; Yaden BC; Karin M
    J Hepatol; 2023 Aug; 79(2):362-377. PubMed ID: 36996941
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2α-ATF4 pathway.
    Kim HJ; Joe Y; Kim SK; Park SU; Park J; Chen Y; Kim J; Ryu J; Cho GJ; Surh YJ; Ryter SW; Kim UH; Chung HT
    Free Radic Biol Med; 2017 Sep; 110():81-91. PubMed ID: 28578014
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ER stress-induced upregulation of NNMT contributes to alcohol-related fatty liver development.
    Song Q; Chen Y; Wang J; Hao L; Huang C; Griffiths A; Sun Z; Zhou Z; Song Z
    J Hepatol; 2020 Oct; 73(4):783-793. PubMed ID: 32389809
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Defect of mitochondrial respiratory chain is a mechanism of ROS overproduction in a rat model of alcoholic liver disease: role of zinc deficiency.
    Sun Q; Zhong W; Zhang W; Zhou Z
    Am J Physiol Gastrointest Liver Physiol; 2016 Feb; 310(3):G205-14. PubMed ID: 26585415
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rifampicin protects PC12 cells from rotenone-induced cytotoxicity by activating GRP78 via PERK-eIF2α-ATF4 pathway.
    Jing X; Shi Q; Bi W; Zeng Z; Liang Y; Wu X; Xiao S; Liu J; Yang L; Tao E
    PLoS One; 2014; 9(3):e92110. PubMed ID: 24638036
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2.
    Saito A; Ochiai K; Kondo S; Tsumagari K; Murakami T; Cavener DR; Imaizumi K
    J Biol Chem; 2011 Feb; 286(6):4809-18. PubMed ID: 21135100
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease.
    Guo W; Zhong W; Hao L; Dong H; Sun X; Yue R; Li T; Zhou Z
    Cell Mol Gastroenterol Hepatol; 2021; 12(5):1599-1615. PubMed ID: 34284164
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival.
    Walter F; Schmid J; Düssmann H; Concannon CG; Prehn JH
    Cell Death Differ; 2015 Sep; 22(9):1502-16. PubMed ID: 25633195
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of mTORC1 by Free Fatty Acids Suppresses LAMP2 and Autophagy Function via ER Stress in Alcohol-Related Liver Disease.
    Guo W; Zhong W; Hao L; Sun X; Zhou Z
    Cells; 2021 Oct; 10(10):. PubMed ID: 34685712
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antioxidative effects of polypyrimidine tract-binding protein-associated splicing factor against pathological retinal angiogenesis through promotion of mitochondrial function.
    Dong L; Lin T; Li W; Hong Y; Ren X; Ke Y; Zhang X; Li X
    J Mol Med (Berl); 2021 Jul; 99(7):967-980. PubMed ID: 33770188
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gastrodin alleviates mitochondrial dysfunction by regulating SIRT3-mediated TFAM acetylation in vascular dementia.
    Chen YX; Yang H; Wang DS; Chen TT; Qi XL; Tao L; Chen Y; Shen XC
    Phytomedicine; 2024 Jun; 128():155369. PubMed ID: 38547618
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial translation inhibition triggers ATF4 activation, leading to integrated stress response but not to mitochondrial unfolded protein response.
    Sasaki K; Uchiumi T; Toshima T; Yagi M; Do Y; Hirai H; Igami K; Gotoh K; Kang D
    Biosci Rep; 2020 Nov; 40(11):. PubMed ID: 33165592
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin-induced genes INSIG1 and INSIG2 mediate oxysterol-dependent activation of the PERK-eIF2α-ATF4 axis.
    Watanabe Y; Sasaki T; Miyoshi S; Shimizu M; Yamauchi Y; Sato R
    J Biol Chem; 2021 Aug; 297(2):100989. PubMed ID: 34298014
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Loss of long-chain acyl-CoA synthetase 1 promotes hepatocyte death in alcohol-induced steatohepatitis.
    Dong H; Zhong W; Zhang W; Hao L; Guo W; Yue R; Sun X; Sun Z; Bataller R; Zhou Z
    Metabolism; 2023 Jan; 138():155334. PubMed ID: 36349655
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lutein upregulates the PGC-1α, NRF1, and TFAM expression by AMPK activation and downregulates ROS to maintain mtDNA integrity and mitochondrial biogenesis in hyperglycemic ARPE-19 cells and rat retina.
    Nanjaiah H; Vallikannan B
    Biotechnol Appl Biochem; 2019 Nov; 66(6):999-1009. PubMed ID: 31529536
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nicotinamide N-methyltransferase upregulation via the mTORC1-ATF4 pathway activation contributes to palmitate-induced lipotoxicity in hepatocytes.
    Griffiths A; Wang J; Song Q; Iyamu ID; Liu L; Park J; Jiang Y; Huang R; Song Z
    Am J Physiol Cell Physiol; 2021 Sep; 321(3):C585-C595. PubMed ID: 34378991
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.