BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

772 related articles for article (PubMed ID: 33177178)

  • 21. Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy.
    von Coelln R; Thomas B; Andrabi SA; Lim KL; Savitt JM; Saffary R; Stirling W; Bruno K; Hess EJ; Lee MK; Dawson VL; Dawson TM
    J Neurosci; 2006 Apr; 26(14):3685-96. PubMed ID: 16597723
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Recapitulating Parkinson's disease pathology in a three-dimensional human neural cell culture model.
    Taylor-Whiteley TR; Le Maitre CL; Duce JA; Dalton CF; Smith DP
    Dis Model Mech; 2019 Apr; 12(4):. PubMed ID: 30926586
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates.
    Volpicelli-Daley LA; Luk KC; Lee VM
    Nat Protoc; 2014 Sep; 9(9):2135-46. PubMed ID: 25122523
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions.
    Stoyka LE; Arrant AE; Thrasher DR; Russell DL; Freire J; Mahoney CL; Narayanan A; Dib AG; Standaert DG; Volpicelli-Daley LA
    Neurobiol Dis; 2020 Feb; 134():104708. PubMed ID: 31837424
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes.
    Chu Y; Muller S; Tavares A; Barret O; Alagille D; Seibyl J; Tamagnan G; Marek K; Luk KC; Trojanowski JQ; Lee VMY; Kordower JH
    Brain; 2019 Nov; 142(11):3565-3579. PubMed ID: 31580415
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Propagation of pathological α-synuclein in marmoset brain.
    Shimozawa A; Ono M; Takahara D; Tarutani A; Imura S; Masuda-Suzukake M; Higuchi M; Yanai K; Hisanaga SI; Hasegawa M
    Acta Neuropathol Commun; 2017 Feb; 5(1):12. PubMed ID: 28148299
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells.
    Rott R; Szargel R; Haskin J; Shani V; Shainskaya A; Manov I; Liani E; Avraham E; Engelender S
    J Biol Chem; 2008 Feb; 283(6):3316-3328. PubMed ID: 18070888
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Effects of Alpha-Synuclein Targeted Antisense Oligonucleotides on Lewy Body-Like Pathology and Behavioral Disturbances Induced by Injections of Pre-Formed Fibrils in the Mouse Motor Cortex.
    Boutros SW; Raber J; Unni VK
    J Parkinsons Dis; 2021; 11(3):1091-1115. PubMed ID: 34057097
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells.
    Vasili E; Dominguez-Meijide A; Flores-León M; Al-Azzani M; Kanellidi A; Melki R; Stefanis L; Outeiro TF
    Mol Neurobiol; 2022 Feb; 59(2):1273-1284. PubMed ID: 34984585
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Phosphorylated exogenous alpha-synuclein fibrils exacerbate pathology and induce neuronal dysfunction in mice.
    Karampetsou M; Ardah MT; Semitekolou M; Polissidis A; Samiotaki M; Kalomoiri M; Majbour N; Xanthou G; El-Agnaf OMA; Vekrellis K
    Sci Rep; 2017 Nov; 7(1):16533. PubMed ID: 29184069
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Expression of α-synuclein is regulated in a neuronal cell type-dependent manner.
    Taguchi K; Watanabe Y; Tsujimura A; Tanaka M
    Anat Sci Int; 2019 Jan; 94(1):11-22. PubMed ID: 30362073
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration.
    Wang X; Becker K; Levine N; Zhang M; Lieberman AP; Moore DJ; Ma J
    Acta Neuropathol Commun; 2019 Mar; 7(1):41. PubMed ID: 30871620
    [TBL] [Abstract][Full Text] [Related]  

  • 33. α-Synuclein and Lewy pathology in Parkinson's disease.
    Kalia LV; Kalia SK
    Curr Opin Neurol; 2015 Aug; 28(4):375-81. PubMed ID: 26110807
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Is Cell Death Primary or Secondary in the Pathophysiology of Idiopathic Parkinson's Disease?
    Schulz-Schaeffer WJ
    Biomolecules; 2015 Jul; 5(3):1467-79. PubMed ID: 26193328
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Unbiased Proteomics of Early Lewy Body Formation Model Implicates Active Microtubule Affinity-Regulating Kinases (MARKs) in Synucleinopathies.
    Henderson MX; Chung CH; Riddle DM; Zhang B; Gathagan RJ; Seeholzer SH; Trojanowski JQ; Lee VMY
    J Neurosci; 2017 Jun; 37(24):5870-5884. PubMed ID: 28522732
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Tissue transglutaminase-induced aggregation of alpha-synuclein: Implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies.
    Junn E; Ronchetti RD; Quezado MM; Kim SY; Mouradian MM
    Proc Natl Acad Sci U S A; 2003 Feb; 100(4):2047-52. PubMed ID: 12576551
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.
    Uemura N; Yagi H; Uemura MT; Hatanaka Y; Yamakado H; Takahashi R
    Mol Neurodegener; 2018 May; 13(1):21. PubMed ID: 29751824
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Initiation and propagation of α-synuclein aggregation in the nervous system.
    Hijaz BA; Volpicelli-Daley LA
    Mol Neurodegener; 2020 Mar; 15(1):19. PubMed ID: 32143659
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Leveraging the preformed fibril model to distinguish between alpha-synuclein inclusion- and nigrostriatal degeneration-associated immunogenicity.
    Stoll AC; Sortwell CE
    Neurobiol Dis; 2022 Sep; 171():105804. PubMed ID: 35764290
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity.
    Ostrerova-Golts N; Petrucelli L; Hardy J; Lee JM; Farer M; Wolozin B
    J Neurosci; 2000 Aug; 20(16):6048-54. PubMed ID: 10934254
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 39.