These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

577 related articles for article (PubMed ID: 33178678)

  • 1. Inhibition of α-Synuclein Aggregation and Mature Fibril Disassembling With a Minimalistic Compound, ZPDm.
    Peña-Díaz S; Pujols J; Pinheiro F; Santos J; Pallarés I; Navarro S; Conde-Gimenez M; García J; Salvatella X; Dalfó E; Sancho J; Ventura S
    Front Bioeng Biotechnol; 2020; 8():588947. PubMed ID: 33178678
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ZPD-2, a Small Compound That Inhibits α-Synuclein Amyloid Aggregation and Its Seeded Polymerization.
    Peña-Díaz S; Pujols J; Conde-Giménez M; Čarija A; Dalfo E; García J; Navarro S; Pinheiro F; Santos J; Salvatella X; Sancho J; Ventura S
    Front Mol Neurosci; 2019; 12():306. PubMed ID: 31920537
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
    Pujols J; Peña-Díaz S; Lázaro DF; Peccati F; Pinheiro F; González D; Carija A; Navarro S; Conde-Giménez M; García J; Guardiola S; Giralt E; Salvatella X; Sancho J; Sodupe M; Outeiro TF; Dalfó E; Ventura S
    Proc Natl Acad Sci U S A; 2018 Oct; 115(41):10481-10486. PubMed ID: 30249646
    [TBL] [Abstract][Full Text] [Related]  

  • 4. One ring is sufficient to inhibit α-synuclein aggregation.
    Pena-DIaz S; Ventura S
    Neural Regen Res; 2022 Mar; 17(3):508-511. PubMed ID: 34380879
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils.
    Murray KA; Hu CJ; Pan H; Lu J; Abskharon R; Bowler JT; Rosenberg GM; Williams CK; Elezi G; Balbirnie M; Faull KF; Vinters HV; Seidler PM; Eisenberg DS
    Proc Natl Acad Sci U S A; 2023 Feb; 120(7):e2217835120. PubMed ID: 36757890
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Divergent effects of the H50Q and G51D SNCA mutations on the aggregation of α-synuclein.
    Rutherford NJ; Moore BD; Golde TE; Giasson BI
    J Neurochem; 2014 Dec; 131(6):859-67. PubMed ID: 24984882
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts.
    Ardah MT; Ghanem SS; Abdulla SA; Lv G; Emara MM; Paleologou KE; Vaikath NN; Lu JH; Li M; Vekrellis K; Eliezer D; El-Agnaf OMA
    BMC Complement Med Ther; 2020 Mar; 20(1):73. PubMed ID: 32143619
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dissociation of amyloid fibrils of alpha-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities.
    Foguel D; Suarez MC; Ferrão-Gonzales AD; Porto TC; Palmieri L; Einsiedler CM; Andrade LR; Lashuel HA; Lansbury PT; Kelly JW; Silva JL
    Proc Natl Acad Sci U S A; 2003 Aug; 100(17):9831-6. PubMed ID: 12900507
    [TBL] [Abstract][Full Text] [Related]  

  • 9. High-Throughput Screening Methodology to Identify Alpha-Synuclein Aggregation Inhibitors.
    Pujols J; Peña-Díaz S; Conde-Giménez M; Pinheiro F; Navarro S; Sancho J; Ventura S
    Int J Mol Sci; 2017 Mar; 18(3):. PubMed ID: 28257086
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anti-amyloid compounds inhibit α-synuclein aggregation induced by protein misfolding cyclic amplification (PMCA).
    Herva ME; Zibaee S; Fraser G; Barker RA; Goedert M; Spillantini MG
    J Biol Chem; 2014 Apr; 289(17):11897-11905. PubMed ID: 24584936
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analysis of sheep α-synuclein provides a molecular strategy for the reduction of fibrillation.
    Bickle L; Hopwood JJ; Karageorgos L
    Biochim Biophys Acta Proteins Proteom; 2017 Mar; 1865(3):261-273. PubMed ID: 28007442
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural Optimization of Inhibitors of α-Synuclein Fibril Growth: Affinity to the Fibril End as a Crucial Factor.
    Afitska K; Priss A; Yushchenko DA; Shvadchak VV
    J Mol Biol; 2020 Feb; 432(4):967-977. PubMed ID: 31809698
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amplification of distinct α-synuclein fibril conformers through protein misfolding cyclic amplification.
    Jung BC; Lim YJ; Bae EJ; Lee JS; Choi MS; Lee MK; Lee HJ; Kim YS; Lee SJ
    Exp Mol Med; 2017 Apr; 49(4):e314. PubMed ID: 28386127
    [TBL] [Abstract][Full Text] [Related]  

  • 14. α-Synuclein aggregation at low concentrations.
    Afitska K; Fucikova A; Shvadchak VV; Yushchenko DA
    Biochim Biophys Acta Proteins Proteom; 2019; 1867(7-8):701-709. PubMed ID: 31096048
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polyphenol Honokiol and Flavone 2',3',4'-Trihydroxyflavone Differentially Interact with α-Synuclein at Distinct Phases of Aggregation.
    Jovcevski B; Das S; Smid S; Pukala TL
    ACS Chem Neurosci; 2020 Dec; 11(24):4469-4477. PubMed ID: 33185419
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparison of the in vivo induction and transmission of α-synuclein pathology by mutant α-synuclein fibril seeds in transgenic mice.
    Rutherford NJ; Dhillon JS; Riffe CJ; Howard JK; Brooks M; Giasson BI
    Hum Mol Genet; 2017 Dec; 26(24):4906-4915. PubMed ID: 29036344
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crocin Inhibits the Fibrillation of Human α-synuclein and Disassembles Mature Fibrils: Experimental Findings and Mechanistic Insights from Molecular Dynamics Simulation.
    Saffari B; Amininasab M
    ACS Chem Neurosci; 2021 Nov; 12(21):4037-4057. PubMed ID: 34636232
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Curcumin Pyrazole and its derivative (N-(3-Nitrophenylpyrazole) Curcumin inhibit aggregation, disrupt fibrils and modulate toxicity of Wild type and Mutant α-Synuclein.
    Ahsan N; Mishra S; Jain MK; Surolia A; Gupta S
    Sci Rep; 2015 May; 5():9862. PubMed ID: 25985292
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.
    Perni M; Flagmeier P; Limbocker R; Cascella R; Aprile FA; Galvagnion C; Heller GT; Meisl G; Chen SW; Kumita JR; Challa PK; Kirkegaard JB; Cohen SIA; Mannini B; Barbut D; Nollen EAA; Cecchi C; Cremades N; Knowles TPJ; Chiti F; Zasloff M; Vendruscolo M; Dobson CM
    ACS Chem Biol; 2018 Aug; 13(8):2308-2319. PubMed ID: 29953201
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stereotaxic Targeting of Alpha-Synuclein Pathology in Mouse Brain Using Preformed Fibrils.
    Zhang B; Kehm V; Gathagan R; Leight SN; Trojanowski JQ; Lee VM; Luk KC
    Methods Mol Biol; 2019; 1948():45-57. PubMed ID: 30771169
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.