BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 33198243)

  • 1. Mitochondrial Carriers Regulating Insulin Secretion Profiled in Human Islets upon Metabolic Stress.
    Jimenez-Sánchez C; Brun T; Maechler P
    Biomolecules; 2020 Nov; 10(11):. PubMed ID: 33198243
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets.
    Brun T; Li N; Jourdain AA; Gaudet P; Duhamel D; Meyer J; Bosco D; Maechler P
    Hum Mol Genet; 2015 Sep; 24(18):5270-84. PubMed ID: 26123492
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Essential role of mitochondrial Ca2+ uniporter in the generation of mitochondrial pH gradient and metabolism-secretion coupling in insulin-releasing cells.
    Quan X; Nguyen TT; Choi SK; Xu S; Das R; Cha SK; Kim N; Han J; Wiederkehr A; Wollheim CB; Park KS
    J Biol Chem; 2015 Feb; 290(7):4086-96. PubMed ID: 25548283
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stress-induced dissociations between intracellular calcium signaling and insulin secretion in pancreatic islets.
    Qureshi FM; Dejene EA; Corbin KL; Nunemaker CS
    Cell Calcium; 2015 May; 57(5-6):366-375. PubMed ID: 25861744
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Changes in mitochondrial carriers exhibit stress-specific signatures in INS-1Eβ-cells exposed to glucose versus fatty acids.
    Brun T; Scarcia P; Li N; Gaudet P; Duhamel D; Palmieri F; Maechler P
    PLoS One; 2013; 8(12):e82364. PubMed ID: 24349266
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mitochondrial function and insulin secretion.
    Maechler P
    Mol Cell Endocrinol; 2013 Oct; 379(1-2):12-8. PubMed ID: 23792187
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pancreatic β-cell Na+ channels control global Ca2+ signaling and oxidative metabolism by inducing Na+ and Ca2+ responses that are propagated into mitochondria.
    Nita II; Hershfinkel M; Kantor C; Rutter GA; Lewis EC; Sekler I
    FASEB J; 2014 Aug; 28(8):3301-12. PubMed ID: 24719357
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Beta-cell mitochondrial carriers and the diabetogenic stress response.
    Brun T; Maechler P
    Biochim Biophys Acta; 2016 Oct; 1863(10):2540-9. PubMed ID: 26979549
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrial glutamate carrier GC1 as a newly identified player in the control of glucose-stimulated insulin secretion.
    Casimir M; Lasorsa FM; Rubi B; Caille D; Palmieri F; Meda P; Maechler P
    J Biol Chem; 2009 Sep; 284(37):25004-14. PubMed ID: 19584051
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets.
    Lee B; Miles PD; Vargas L; Luan P; Glasco S; Kushnareva Y; Kornbrust ES; Grako KA; Wollheim CB; Maechler P; Olefsky JM; Anderson CM
    Diabetes; 2003 Apr; 52(4):965-73. PubMed ID: 12663468
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells.
    Huypens P; Pillai R; Sheinin T; Schaefer S; Huang M; Odegaard ML; Ronnebaum SM; Wettig SD; Joseph JW
    Diabetologia; 2011 Jan; 54(1):135-45. PubMed ID: 20949348
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AMPK Profiling in Rodent and Human Pancreatic Beta-Cells under Nutrient-Rich Metabolic Stress.
    Brun T; Jiménez-Sánchez C; Madsen JGS; Hadadi N; Duhamel D; Bartley C; Oberhauser L; Trajkovski M; Mandrup S; Maechler P
    Int J Mol Sci; 2020 Jun; 21(11):. PubMed ID: 32492936
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential Effect of Glucose on ER-Mitochondria Ca
    Dingreville F; Panthu B; Thivolet C; Ducreux S; Gouriou Y; Pesenti S; Chauvin MA; Chikh K; Errazuriz-Cerda E; Van Coppenolle F; Rieusset J; Madec AM
    Diabetes; 2019 Sep; 68(9):1778-1794. PubMed ID: 31175102
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells.
    Rubi B; del Arco A; Bartley C; Satrustegui J; Maechler P
    J Biol Chem; 2004 Dec; 279(53):55659-66. PubMed ID: 15494407
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.
    Odegaard ML; Joseph JW; Jensen MV; Lu D; Ilkayeva O; Ronnebaum SM; Becker TC; Newgard CB
    J Biol Chem; 2010 May; 285(22):16530-7. PubMed ID: 20356834
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Involvement of dying beta cell originated messenger molecules in differentiation of pancreatic mesenchymal stem cells under glucotoxic and glucolipotoxic conditions.
    Gezginci-Oktayoglu S; Onay-Ucar E; Sancar-Bas S; Karatug-Kacar A; Arda ESN; Bolkent S
    J Cell Physiol; 2018 May; 233(5):4235-4244. PubMed ID: 29058819
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intra-islet PACAP protects pancreatic β-cells against glucotoxicity and lipotoxicity.
    Nakata M; Shintani N; Hashimoto H; Baba A; Yada T
    J Mol Neurosci; 2010 Nov; 42(3):404-10. PubMed ID: 20461496
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Unraveling the significance of PPP1R1A gene in pancreatic β-cell function: A study in INS-1 cells and human pancreatic islets.
    Taneera J; Mohammed AK; Khalique A; Mussa BM; Sulaiman N; Bustanji Y; Saleh MA; Madkour M; Abu-Gharbieh E; El-Huneidi W
    Life Sci; 2024 May; 345():122608. PubMed ID: 38574885
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The impairment of glucose-stimulated insulin secretion in pancreatic β-cells caused by prolonged glucotoxicity and lipotoxicity is associated with elevated adaptive antioxidant response.
    Fu J; Cui Q; Yang B; Hou Y; Wang H; Xu Y; Wang D; Zhang Q; Pi J
    Food Chem Toxicol; 2017 Feb; 100():161-167. PubMed ID: 28027979
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm.
    Matschinsky FM
    Diabetes; 1996 Feb; 45(2):223-41. PubMed ID: 8549869
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.