183 related articles for article (PubMed ID: 33199508)
21. Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA.
Shen JC; Loeb LA
Nucleic Acids Res; 2000 Sep; 28(17):3260-8. PubMed ID: 10954593
[TBL] [Abstract][Full Text] [Related]
22. Enzymatic mechanism of the WRN helicase/nuclease.
Brosh RM; Opresko PL; Bohr VA
Methods Enzymol; 2006; 409():52-85. PubMed ID: 16793395
[TBL] [Abstract][Full Text] [Related]
23. Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein.
Hu JS; Feng H; Zeng W; Lin GX; Xi XG
Proc Natl Acad Sci U S A; 2005 Dec; 102(51):18379-84. PubMed ID: 16339893
[TBL] [Abstract][Full Text] [Related]
24. Discovering potential WRN inhibitors from natural product database through computational methods.
Jiang T; Zhang Y; Yu S; Hu B
J Mol Graph Model; 2024 Jun; 129():108758. PubMed ID: 38507856
[TBL] [Abstract][Full Text] [Related]
25. Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex.
Li B; Comai L
J Biol Chem; 2001 Mar; 276(13):9896-902. PubMed ID: 11152456
[TBL] [Abstract][Full Text] [Related]
26. Inhibition of Werner syndrome helicase activity by benzo[c]phenanthrene diol epoxide dA adducts in DNA is both strand-and stereoisomer-dependent.
Driscoll HC; Matson SW; Sayer JM; Kroth H; Jerina DM; Brosh RM
J Biol Chem; 2003 Oct; 278(42):41126-35. PubMed ID: 12881525
[TBL] [Abstract][Full Text] [Related]
27. Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes.
Newman JA; Savitsky P; Allerston CK; Bizard AH; Özer Ö; Sarlós K; Liu Y; Pardon E; Steyaert J; Hickson ID; Gileadi O
Nucleic Acids Res; 2015 May; 43(10):5221-35. PubMed ID: 25901030
[TBL] [Abstract][Full Text] [Related]
28. Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation.
Karmakar P; Piotrowski J; Brosh RM; Sommers JA; Miller SP; Cheng WH; Snowden CM; Ramsden DA; Bohr VA
J Biol Chem; 2002 May; 277(21):18291-302. PubMed ID: 11889123
[TBL] [Abstract][Full Text] [Related]
29. Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA.
Swan MK; Legris V; Tanner A; Reaper PM; Vial S; Bordas R; Pollard JR; Charlton PA; Golec JM; Bertrand JA
Acta Crystallogr D Biol Crystallogr; 2014 May; 70(Pt 5):1465-75. PubMed ID: 24816114
[TBL] [Abstract][Full Text] [Related]
30. Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity.
Friedemann J; Grosse F; Zhang S
J Biol Chem; 2005 Sep; 280(35):31303-13. PubMed ID: 15995249
[TBL] [Abstract][Full Text] [Related]
31. Werner Syndrome Protein and DNA Replication.
Mukherjee S; Sinha D; Bhattacharya S; Srinivasan K; Abdisalaam S; Asaithamby A
Int J Mol Sci; 2018 Nov; 19(11):. PubMed ID: 30400178
[TBL] [Abstract][Full Text] [Related]
32. The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins.
Liu Z; Macias MJ; Bottomley MJ; Stier G; Linge JP; Nilges M; Bork P; Sattler M
Structure; 1999 Dec; 7(12):1557-66. PubMed ID: 10647186
[TBL] [Abstract][Full Text] [Related]
33. In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication.
Sharma S; Sommers JA; Brosh RM
Hum Mol Genet; 2004 Oct; 13(19):2247-61. PubMed ID: 15282207
[TBL] [Abstract][Full Text] [Related]
34. p53 modulates RPA-dependent and RPA-independent WRN helicase activity.
Sommers JA; Sharma S; Doherty KM; Karmakar P; Yang Q; Kenny MK; Harris CC; Brosh RM
Cancer Res; 2005 Feb; 65(4):1223-33. PubMed ID: 15735006
[TBL] [Abstract][Full Text] [Related]
35. Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A.
Choudhary S; Doherty KM; Handy CJ; Sayer JM; Yagi H; Jerina DM; Brosh RM
J Biol Chem; 2006 Mar; 281(9):6000-9. PubMed ID: 16380375
[TBL] [Abstract][Full Text] [Related]
36. A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN).
Sommers JA; Kulikowicz T; Croteau DL; Dexheimer T; Dorjsuren D; Jadhav A; Maloney DJ; Simeonov A; Bohr VA; Brosh RM
PLoS One; 2019; 14(1):e0210525. PubMed ID: 30625228
[TBL] [Abstract][Full Text] [Related]
37. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.
Chen L; Huang S; Lee L; Davalos A; Schiestl RH; Campisi J; Oshima J
Aging Cell; 2003 Aug; 2(4):191-9. PubMed ID: 12934712
[TBL] [Abstract][Full Text] [Related]
38. Repeat expansions confer WRN dependence in microsatellite-unstable cancers.
van Wietmarschen N; Sridharan S; Nathan WJ; Tubbs A; Chan EM; Callen E; Wu W; Belinky F; Tripathi V; Wong N; Foster K; Noorbakhsh J; Garimella K; Cruz-Migoni A; Sommers JA; Huang Y; Borah AA; Smith JT; Kalfon J; Kesten N; Fugger K; Walker RL; Dolzhenko E; Eberle MA; Hayward BE; Usdin K; Freudenreich CH; Brosh RM; West SC; McHugh PJ; Meltzer PS; Bass AJ; Nussenzweig A
Nature; 2020 Oct; 586(7828):292-298. PubMed ID: 32999459
[TBL] [Abstract][Full Text] [Related]
39. Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN.
Kitano K; Kim SY; Hakoshima T
Structure; 2010 Feb; 18(2):177-87. PubMed ID: 20159463
[TBL] [Abstract][Full Text] [Related]
40. Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.
Opresko PL; Laine JP; Brosh RM; Seidman MM; Bohr VA
J Biol Chem; 2001 Nov; 276(48):44677-87. PubMed ID: 11572872
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
