BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 33202731)

  • 1. Not All Wnt Activation Is Equal: Ligand-Dependent versus Ligand-Independent Wnt Activation in Colorectal Cancer.
    Kleeman SO; Leedham SJ
    Cancers (Basel); 2020 Nov; 12(11):. PubMed ID: 33202731
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of RNF43 frameshift mutations that drive Wnt ligand- and R-spondin-dependent colon cancer.
    Yamamoto D; Oshima H; Wang D; Takeda H; Kita K; Lei X; Nakayama M; Murakami K; Ohama T; Takemura H; Toyota M; Suzuki H; Inaki N; Oshima M
    J Pathol; 2022 May; 257(1):39-52. PubMed ID: 35040131
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer.
    Hao HX; Jiang X; Cong F
    Cancers (Basel); 2016 Jun; 8(6):. PubMed ID: 27338477
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular genetics and targeted therapy of WNT-related human diseases (Review).
    Katoh M; Katoh M
    Int J Mol Med; 2017 Sep; 40(3):587-606. PubMed ID: 28731148
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification.
    Kleeman SO; Koelzer VH; Jones HJ; Vazquez EG; Davis H; East JE; Arnold R; Koppens MA; Blake A; Domingo E; Cunningham C; Beggs AD; Pestinger V; Loughrey MB; Wang LM; Lannagan TR; Woods SL; Worthley D; Consortium SC; Tomlinson I; Dunne PD; Maughan T; Leedham SJ
    Gut; 2020 Jun; 69(6):1092-1103. PubMed ID: 31563876
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer.
    Seeber A; Battaglin F; Zimmer K; Kocher F; Baca Y; Xiu J; Spizzo G; Novotny-Diermayr V; Rieder D; Puccini A; Swensen J; Ellis M; Goldberg RM; Grothey A; Shields AF; Marshall JL; Weinberg BA; Sackstein PE; Lim KH; Tan GS; Nabhan C; Korn WM; Amann A; Trajanoski Z; Berger MD; Lou E; Wolf D; Lenz HJ
    Clin Cancer Res; 2022 May; 28(9):1863-1870. PubMed ID: 35254413
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.
    Hilkens J; Timmer NC; Boer M; Ikink GJ; Schewe M; Sacchetti A; Koppens MAJ; Song JY; Bakker ERM
    Gut; 2017 Jun; 66(6):1095-1105. PubMed ID: 27511199
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations.
    Fischer MM; Yeung VP; Cattaruzza F; Hussein R; Yen WC; Murriel C; Evans JW; O'Young G; Brunner AL; Wang M; Cain J; Cancilla B; Kapoun A; Hoey T
    Sci Rep; 2017 Nov; 7(1):15270. PubMed ID: 29127379
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Role of WNT Pathway Mutations in Cancer Development and an Overview of Therapeutic Options.
    Groenewald W; Lund AH; Gay DM
    Cells; 2023 Mar; 12(7):. PubMed ID: 37048063
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Frequent PTPRK-RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma.
    Sekine S; Yamashita S; Tanabe T; Hashimoto T; Yoshida H; Taniguchi H; Kojima M; Shinmura K; Saito Y; Hiraoka N; Ushijima T; Ochiai A
    J Pathol; 2016 Jun; 239(2):133-8. PubMed ID: 26924569
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer Therapy.
    Hinze L; Labrosse R; Degar J; Han T; Schatoff EM; Schreek S; Karim S; McGuckin C; Sacher JR; Wagner F; Stanulla M; Yuan C; Sicinska E; Giannakis M; Ng K; Dow LE; Gutierrez A
    Cancer Discov; 2020 Nov; 10(11):1690-1705. PubMed ID: 32703769
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clinicopathological and molecular correlations in traditional serrated adenoma.
    Sekine S; Yamashita S; Yamada M; Hashimoto T; Ogawa R; Yoshida H; Taniguchi H; Kojima M; Ushijima T; Saito Y
    J Gastroenterol; 2020 Apr; 55(4):418-427. PubMed ID: 32052185
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation.
    Yan HHN; Lai JCW; Ho SL; Leung WK; Law WL; Lee JFY; Chan AKW; Tsui WY; Chan ASY; Lee BCH; Yue SSK; Man AHY; Clevers H; Yuen ST; Leung SY
    Gut; 2017 Sep; 66(9):1645-1656. PubMed ID: 27329244
    [TBL] [Abstract][Full Text] [Related]  

  • 14. EIF3E-RSPO2 and PIEZO1-RSPO2 fusions in colorectal traditional serrated adenoma.
    Hashimoto T; Ogawa R; Yoshida H; Taniguchi H; Kojima M; Saito Y; Sekine S
    Histopathology; 2019 Aug; 75(2):266-273. PubMed ID: 30916365
    [TBL] [Abstract][Full Text] [Related]  

  • 15. R-spondin-3 is an oncogenic driver of poorly differentiated invasive breast cancer.
    Ter Steege EJ; Boer M; Timmer NC; Ammerlaan CM; Song JY; Derksen PW; Hilkens J; Bakker ER
    J Pathol; 2022 Nov; 258(3):289-299. PubMed ID: 36106661
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer.
    Hashimoto T; Takayanagi D; Yonemaru J; Naka T; Nagashima K; Yatabe Y; Shida D; Hamamoto R; Kleeman SO; Leedham SJ; Maughan T; Takashima A; Shiraishi K; Sekine S
    Br J Cancer; 2022 Oct; 127(6):1043-1050. PubMed ID: 35715628
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish.
    Valvezan AJ; Huang J; Lengner CJ; Pack M; Klein PS
    Dis Model Mech; 2014 Jan; 7(1):63-71. PubMed ID: 24092877
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Wnt Pathway Inhibitor RXC004 Blocks Tumor Growth and Reverses Immune Evasion in Wnt Ligand-dependent Cancer Models.
    Phillips C; Bhamra I; Eagle C; Flanagan E; Armer R; Jones CD; Bingham M; Calcraft P; Edmenson Cook A; Thompson B; Woodcock SA
    Cancer Res Commun; 2022 Sep; 2(9):914-928. PubMed ID: 36922934
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comprehensive characterization of RSPO fusions in colorectal traditional serrated adenomas.
    Sekine S; Ogawa R; Hashimoto T; Motohiro K; Yoshida H; Taniguchi H; Saito Y; Yasuhiro O; Ochiai A; Hiraoka N
    Histopathology; 2017 Oct; 71(4):601-609. PubMed ID: 28543708
    [TBL] [Abstract][Full Text] [Related]  

  • 20. R-spondins can potentiate WNT signaling without LGRs.
    Lebensohn AM; Rohatgi R
    Elife; 2018 Feb; 7():. PubMed ID: 29405118
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.