272 related articles for article (PubMed ID: 33202731)
1. Not All Wnt Activation Is Equal: Ligand-Dependent versus Ligand-Independent Wnt Activation in Colorectal Cancer.
Kleeman SO; Leedham SJ
Cancers (Basel); 2020 Nov; 12(11):. PubMed ID: 33202731
[TBL] [Abstract][Full Text] [Related]
2. Characterization of RNF43 frameshift mutations that drive Wnt ligand- and R-spondin-dependent colon cancer.
Yamamoto D; Oshima H; Wang D; Takeda H; Kita K; Lei X; Nakayama M; Murakami K; Ohama T; Takemura H; Toyota M; Suzuki H; Inaki N; Oshima M
J Pathol; 2022 May; 257(1):39-52. PubMed ID: 35040131
[TBL] [Abstract][Full Text] [Related]
3. Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer.
Hao HX; Jiang X; Cong F
Cancers (Basel); 2016 Jun; 8(6):. PubMed ID: 27338477
[TBL] [Abstract][Full Text] [Related]
4. Molecular genetics and targeted therapy of WNT-related human diseases (Review).
Katoh M; Katoh M
Int J Mol Med; 2017 Sep; 40(3):587-606. PubMed ID: 28731148
[TBL] [Abstract][Full Text] [Related]
5. Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification.
Kleeman SO; Koelzer VH; Jones HJ; Vazquez EG; Davis H; East JE; Arnold R; Koppens MA; Blake A; Domingo E; Cunningham C; Beggs AD; Pestinger V; Loughrey MB; Wang LM; Lannagan TR; Woods SL; Worthley D; Consortium SC; Tomlinson I; Dunne PD; Maughan T; Leedham SJ
Gut; 2020 Jun; 69(6):1092-1103. PubMed ID: 31563876
[TBL] [Abstract][Full Text] [Related]
6. Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer.
Seeber A; Battaglin F; Zimmer K; Kocher F; Baca Y; Xiu J; Spizzo G; Novotny-Diermayr V; Rieder D; Puccini A; Swensen J; Ellis M; Goldberg RM; Grothey A; Shields AF; Marshall JL; Weinberg BA; Sackstein PE; Lim KH; Tan GS; Nabhan C; Korn WM; Amann A; Trajanoski Z; Berger MD; Lou E; Wolf D; Lenz HJ
Clin Cancer Res; 2022 May; 28(9):1863-1870. PubMed ID: 35254413
[TBL] [Abstract][Full Text] [Related]
7. RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.
Hilkens J; Timmer NC; Boer M; Ikink GJ; Schewe M; Sacchetti A; Koppens MAJ; Song JY; Bakker ERM
Gut; 2017 Jun; 66(6):1095-1105. PubMed ID: 27511199
[TBL] [Abstract][Full Text] [Related]
8. RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations.
Fischer MM; Yeung VP; Cattaruzza F; Hussein R; Yen WC; Murriel C; Evans JW; O'Young G; Brunner AL; Wang M; Cain J; Cancilla B; Kapoun A; Hoey T
Sci Rep; 2017 Nov; 7(1):15270. PubMed ID: 29127379
[TBL] [Abstract][Full Text] [Related]
9. The Role of WNT Pathway Mutations in Cancer Development and an Overview of Therapeutic Options.
Groenewald W; Lund AH; Gay DM
Cells; 2023 Mar; 12(7):. PubMed ID: 37048063
[TBL] [Abstract][Full Text] [Related]
10. Frequent PTPRK-RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma.
Sekine S; Yamashita S; Tanabe T; Hashimoto T; Yoshida H; Taniguchi H; Kojima M; Shinmura K; Saito Y; Hiraoka N; Ushijima T; Ochiai A
J Pathol; 2016 Jun; 239(2):133-8. PubMed ID: 26924569
[TBL] [Abstract][Full Text] [Related]
11. Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer Therapy.
Hinze L; Labrosse R; Degar J; Han T; Schatoff EM; Schreek S; Karim S; McGuckin C; Sacher JR; Wagner F; Stanulla M; Yuan C; Sicinska E; Giannakis M; Ng K; Dow LE; Gutierrez A
Cancer Discov; 2020 Nov; 10(11):1690-1705. PubMed ID: 32703769
[TBL] [Abstract][Full Text] [Related]
12. Clinicopathological and molecular correlations in traditional serrated adenoma.
Sekine S; Yamashita S; Yamada M; Hashimoto T; Ogawa R; Yoshida H; Taniguchi H; Kojima M; Ushijima T; Saito Y
J Gastroenterol; 2020 Apr; 55(4):418-427. PubMed ID: 32052185
[TBL] [Abstract][Full Text] [Related]
13. RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation.
Yan HHN; Lai JCW; Ho SL; Leung WK; Law WL; Lee JFY; Chan AKW; Tsui WY; Chan ASY; Lee BCH; Yue SSK; Man AHY; Clevers H; Yuen ST; Leung SY
Gut; 2017 Sep; 66(9):1645-1656. PubMed ID: 27329244
[TBL] [Abstract][Full Text] [Related]
14. EIF3E-RSPO2 and PIEZO1-RSPO2 fusions in colorectal traditional serrated adenoma.
Hashimoto T; Ogawa R; Yoshida H; Taniguchi H; Kojima M; Saito Y; Sekine S
Histopathology; 2019 Aug; 75(2):266-273. PubMed ID: 30916365
[TBL] [Abstract][Full Text] [Related]
15. R-spondin-3 is an oncogenic driver of poorly differentiated invasive breast cancer.
Ter Steege EJ; Boer M; Timmer NC; Ammerlaan CM; Song JY; Derksen PW; Hilkens J; Bakker ER
J Pathol; 2022 Nov; 258(3):289-299. PubMed ID: 36106661
[TBL] [Abstract][Full Text] [Related]
16. Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer.
Hashimoto T; Takayanagi D; Yonemaru J; Naka T; Nagashima K; Yatabe Y; Shida D; Hamamoto R; Kleeman SO; Leedham SJ; Maughan T; Takashima A; Shiraishi K; Sekine S
Br J Cancer; 2022 Oct; 127(6):1043-1050. PubMed ID: 35715628
[TBL] [Abstract][Full Text] [Related]
17. Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish.
Valvezan AJ; Huang J; Lengner CJ; Pack M; Klein PS
Dis Model Mech; 2014 Jan; 7(1):63-71. PubMed ID: 24092877
[TBL] [Abstract][Full Text] [Related]
18. The Wnt Pathway Inhibitor RXC004 Blocks Tumor Growth and Reverses Immune Evasion in Wnt Ligand-dependent Cancer Models.
Phillips C; Bhamra I; Eagle C; Flanagan E; Armer R; Jones CD; Bingham M; Calcraft P; Edmenson Cook A; Thompson B; Woodcock SA
Cancer Res Commun; 2022 Sep; 2(9):914-928. PubMed ID: 36922934
[TBL] [Abstract][Full Text] [Related]
19. Comprehensive characterization of RSPO fusions in colorectal traditional serrated adenomas.
Sekine S; Ogawa R; Hashimoto T; Motohiro K; Yoshida H; Taniguchi H; Saito Y; Yasuhiro O; Ochiai A; Hiraoka N
Histopathology; 2017 Oct; 71(4):601-609. PubMed ID: 28543708
[TBL] [Abstract][Full Text] [Related]
20. R-spondins can potentiate WNT signaling without LGRs.
Lebensohn AM; Rohatgi R
Elife; 2018 Feb; 7():. PubMed ID: 29405118
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]