These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 33205588)

  • 21. Nanoparticle-Mediated Co-Delivery of Notch-1 Antibodies and ABT-737 as a Potent Treatment Strategy for Triple-Negative Breast Cancer.
    Valcourt DM; Dang MN; Scully MA; Day ES
    ACS Nano; 2020 Mar; 14(3):3378-3388. PubMed ID: 32083466
    [TBL] [Abstract][Full Text] [Related]  

  • 22. B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins.
    Renault TT; Elkholi R; Bharti A; Chipuk JE
    J Biol Chem; 2014 Sep; 289(38):26481-26491. PubMed ID: 25096574
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design, synthesis, and activity evaluation of broad-spectrum small-molecule inhibitors of anti-apoptotic Bcl-2 family proteins: characteristics of broad-spectrum protein binding and its effects on anti-tumor activity.
    Zheng CH; Yang H; Zhang M; Lu SH; Shi D; Wang J; Chen XH; Ren XH; Liu J; Lv JG; Zhu J; Zhou YJ
    Bioorg Med Chem Lett; 2012 Jan; 22(1):39-44. PubMed ID: 22172701
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells.
    Huang S; Sinicrope FA
    Autophagy; 2010 Feb; 6(2):256-69. PubMed ID: 20104024
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B.
    Rooswinkel RW; van de Kooij B; Verheij M; Borst J
    Cell Death Dis; 2012 Aug; 3(8):e366. PubMed ID: 22875003
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Exploring the conformational and binding properties of unphosphorylated/phosphorylated monomeric and trimeric Bcl-2 through docking and molecular dynamics simulations.
    Zacarías-Lara OJ; Correa-Basurto J; Bello M
    Biopolymers; 2016 Jul; 105(7):393-413. PubMed ID: 27016043
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Differences in the mechanisms of proapoptotic BH3 proteins binding to Bcl-XL and Bcl-2 quantified in live MCF-7 cells.
    Aranovich A; Liu Q; Collins T; Geng F; Dixit S; Leber B; Andrews DW
    Mol Cell; 2012 Mar; 45(6):754-63. PubMed ID: 22464442
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells.
    Mérino D; Khaw SL; Glaser SP; Anderson DJ; Belmont LD; Wong C; Yue P; Robati M; Phipson B; Fairlie WD; Lee EF; Campbell KJ; Vandenberg CJ; Cory S; Roberts AW; Ludlam MJ; Huang DC; Bouillet P
    Blood; 2012 Jun; 119(24):5807-16. PubMed ID: 22538851
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mimicking the BH3 domain to kill cancer cells.
    Ni Chonghaile T; Letai A
    Oncogene; 2008 Dec; 27 Suppl 1(0 1):S149-57. PubMed ID: 19641500
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.
    Park D; Magis AT; Li R; Owonikoko TK; Sica GL; Sun SY; Ramalingam SS; Khuri FR; Curran WJ; Deng X
    Cancer Res; 2013 Sep; 73(17):5485-96. PubMed ID: 23824742
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation.
    Chen S; Dai Y; Harada H; Dent P; Grant S
    Cancer Res; 2007 Jan; 67(2):782-91. PubMed ID: 17234790
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Glycolysis inhibition targets Mcl-1 to restore sensitivity of lymphoma cells to ABT-737-induced apoptosis.
    Meynet O; Bénéteau M; Jacquin MA; Pradelli LA; Cornille A; Carles M; Ricci JE
    Leukemia; 2012 May; 26(5):1145-7. PubMed ID: 22076465
    [No Abstract]   [Full Text] [Related]  

  • 33. A brewing understanding of the regulation of Bax function by Bcl-xL and Bcl-2.
    Renault TT; Dejean LM; Manon S
    Mech Ageing Dev; 2017 Jan; 161(Pt B):201-210. PubMed ID: 27112371
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Long live the cell death!
    Mastino A; Basu S; Brunner T; Ricci JE; Diederich M
    Cell Death Differ; 2008 Aug; 15(8):1330-2. PubMed ID: 18404157
    [No Abstract]   [Full Text] [Related]  

  • 35. Bcl-2-regulated apoptosis: mechanism and therapeutic potential.
    Adams JM; Cory S
    Curr Opin Immunol; 2007 Oct; 19(5):488-96. PubMed ID: 17629468
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The Bcl-2 homology domain 3 (BH3) mimetic ABT-737 reveals the dynamic regulation of bad, a proapoptotic protein of the Bcl-2 family, by Bcl-xL.
    Ezzoukhry Z; Louandre C; François C; Saidak Z; Godin C; Mazière JC; Galmiche A
    Mol Pharmacol; 2011 Jun; 79(6):997-1004. PubMed ID: 21393385
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Allosteric modulation of sigma receptors by BH3 mimetics ABT-737, ABT-263 (Navitoclax) and ABT-199 (Venetoclax).
    Lever JR; Fergason-Cantrell EA
    Pharmacol Res; 2019 Apr; 142():87-100. PubMed ID: 30721730
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Cryptic-site binding mechanism of medium-sized Bcl-xL inhibiting compounds elucidated by McMD-based dynamic docking simulations.
    Bekker GJ; Fukuda I; Higo J; Fukunishi Y; Kamiya N
    Sci Rep; 2021 Mar; 11(1):5046. PubMed ID: 33658550
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Interactions of pro-apoptotic BH3 proteins with anti-apoptotic Bcl-2 family proteins measured in live MCF-7 cells using FLIM FRET.
    Liu Q; Leber B; Andrews DW
    Cell Cycle; 2012 Oct; 11(19):3536-42. PubMed ID: 22895112
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Combined inhibition of Notch signaling and Bcl-2/Bcl-xL results in synergistic antimyeloma effect.
    Li M; Chen F; Clifton N; Sullivan DM; Dalton WS; Gabrilovich DI; Nefedova Y
    Mol Cancer Ther; 2010 Dec; 9(12):3200-9. PubMed ID: 21159606
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.