These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 33205975)

  • 1. Design, Synthesis, and Structure-Activity Relationship Studies of (4-Alkoxyphenyl)glycinamides and Bioisosteric 1,3,4-Oxadiazoles as GPR88 Agonists.
    Rahman MT; Decker AM; Langston TL; Mathews KM; Laudermilk L; Maitra R; Ma W; Darcq E; Kieffer BL; Jin C
    J Med Chem; 2020 Dec; 63(23):14989-15012. PubMed ID: 33205975
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure-Activity Relationship Studies.
    Rahman MT; Decker AM; Laudermilk L; Maitra R; Ma W; Ben Hamida S; Darcq E; Kieffer BL; Jin C
    J Med Chem; 2021 Aug; 64(16):12397-12413. PubMed ID: 34387471
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and pharmacological evaluation of 4-hydroxyphenylglycine and 4-hydroxyphenylglycinol derivatives as GPR88 agonists.
    Jin C; Decker AM; Langston TL
    Bioorg Med Chem; 2017 Jan; 25(2):805-812. PubMed ID: 27956039
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, Synthesis, and Structure-Activity Relationship Studies of Novel GPR88 Agonists (4-Substituted-phenyl)acetamides Based on the Reversed Amide Scaffold.
    Rahman MT; Guan D; Chaminda Lakmal HH; Decker AM; Imler GH; Kerr AT; Harris DL; Jin C
    ACS Chem Neurosci; 2024 Jan; 15(1):169-192. PubMed ID: 38086012
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation.
    Rahman MT; Decker AM; Ben Hamida S; Perrey DA; Chaminda Lakmal HH; Maitra R; Darcq E; Kieffer BL; Jin C
    J Med Chem; 2023 Feb; 66(4):2964-2978. PubMed ID: 36749855
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Optimization of oxadiazole derivatives with a spirocyclic cyclohexane structure as novel GPR119 agonists.
    Harada K; Mizukami J; Watanabe T; Mori G; Ubukata M; Suwa K; Fukuda S; Negoro T; Sato M; Inaba T
    Bioorg Med Chem Lett; 2019 Aug; 29(16):2100-2106. PubMed ID: 31288965
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and structure-activity relationships of 3,4,5-trisubstituted 4,5-dihydro-1,2,4-oxadiazoles as TGR5 agonists.
    Zhu J; Ye Y; Ning M; Mándi A; Feng Y; Zou Q; Kurtán T; Leng Y; Shen J
    ChemMedChem; 2013 Jul; 8(7):1210-23. PubMed ID: 23757200
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of Substitution on the Aniline Moiety of the GPR88 Agonist 2-PCCA: Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies.
    Jin C; Decker AM; Harris DL; Blough BE
    ACS Chem Neurosci; 2016 Oct; 7(10):1418-1432. PubMed ID: 27499251
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of 1, 2, 4-oxadiazole derivatives as novel GPR119 agonists.
    Fu S; Xiang W; Chen J; Ma L; Chen L
    Chem Biol Drug Des; 2017 May; 89(5):815-819. PubMed ID: 27779815
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and pharmacological validation of a novel radioligand for the orphan GPR88 receptor.
    Decker AM; Rahman MT; Kormos CM; Hesk D; Darcq E; Kieffer BL; Jin C
    Bioorg Med Chem Lett; 2023 Jan; 80():129120. PubMed ID: 36587872
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, pharmacological characterization, and structure-activity relationship studies of small molecular agonists for the orphan GPR88 receptor.
    Jin C; Decker AM; Huang XP; Gilmour BP; Blough BE; Roth BL; Hu Y; Gill JB; Zhang XP
    ACS Chem Neurosci; 2014 Jul; 5(7):576-87. PubMed ID: 24793972
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development and validation of a high-throughput calcium mobilization assay for the orphan receptor GPR88.
    Decker AM; Gay EA; Mathews KM; Rosa TC; Langston TL; Maitra R; Jin C
    J Biomed Sci; 2017 Mar; 24(1):23. PubMed ID: 28347302
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88.
    Dzierba CD; Bi Y; Dasgupta B; Hartz RA; Ahuja V; Cianchetta G; Kumi G; Dong L; Aleem S; Fink C; Garcia Y; Green M; Han J; Kwon S; Qiao Y; Wang J; Zhang Y; Liu Y; Zipp G; Liang Z; Burford N; Ferrante M; Bertekap R; Lewis M; Cacace A; Grace J; Wilson A; Nouraldeen A; Westphal R; Kimball D; Carson K; Bronson JJ; Macor JE
    Bioorg Med Chem Lett; 2015 Apr; 25(7):1448-52. PubMed ID: 25690789
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxy)pyridin-4-yl)-1,2,4-oxadiazoles as novel gpr119 agonists.
    Wang Y; Yu M; Zhu J; Zhang JK; Kayser F; Medina JC; Siegler K; Conn M; Shan B; Grillo MP; Liu JJ; Coward P
    Bioorg Med Chem Lett; 2014 Feb; 24(4):1133-7. PubMed ID: 24440299
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mice Lacking GPR88 Show Motor Deficit, Improved Spatial Learning, and Low Anxiety Reversed by Delta Opioid Antagonist.
    Meirsman AC; Le Merrer J; Pellissier LP; Diaz J; Clesse D; Kieffer BL; Becker JA
    Biol Psychiatry; 2016 Jun; 79(11):917-27. PubMed ID: 26188600
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of novel HDAC8 inhibitory 2,5-disubstituted-1,3,4-oxadiazoles containing glycine and alanine hybrids with anti cancer activity.
    Pidugu VR; Yarla NS; Pedada SR; Kalle AM; Satya AK
    Bioorg Med Chem; 2016 Nov; 24(21):5611-5617. PubMed ID: 27665180
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of (E)-5-styryl-1,2,4-oxadiazoles as anti-tubercular agents.
    Atmaram Upare A; Gadekar PK; Sivaramakrishnan H; Naik N; Khedkar VM; Sarkar D; Choudhari A; Mohana Roopan S
    Bioorg Chem; 2019 May; 86():507-512. PubMed ID: 30776681
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of an orally bioavailable alkyl oxadiazole beta3 adrenergic receptor agonist.
    Feng DD; Biftu T; Candelore MR; Cascieri MA; Colwell LF; Deng L; Feeney WP; Forrest MJ; Hom GJ; MacIntyre DE; Miller RR; Stearns RA; Strader CD; Tota L; Wyvratt MJ; Fisher MH; Weber AE
    Bioorg Med Chem Lett; 2000 Jul; 10(13):1427-9. PubMed ID: 10888324
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification and Structure-Activity Relationship (SAR) of potent and selective oxadiazole-based agonists of sphingosine-1-phosphate receptor (S1P
    Liu T; Jin J; Chen Y; Xi Q; Hu J; Jia W; Chen X; Li Y; Wang X; Yin D
    Bioorg Chem; 2019 Feb; 82():41-57. PubMed ID: 30268973
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Use of small-molecule crystal structures to address solubility in a novel series of G protein coupled receptor 119 agonists: optimization of a lead and in vivo evaluation.
    Scott JS; Birch AM; Brocklehurst KJ; Broo A; Brown HS; Butlin RJ; Clarke DS; Davidsson O; Ertan A; Goldberg K; Groombridge SD; Hudson JA; Laber D; Leach AG; Macfaul PA; McKerrecher D; Pickup A; Schofield P; Svensson PH; Sörme P; Teague J
    J Med Chem; 2012 Jun; 55(11):5361-79. PubMed ID: 22545772
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.