BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 33208242)

  • 1. Transformed ALDH2
    Zhang XN; Meng FG; Wang YR; Liu SX; Zeng T
    Med Hypotheses; 2021 Jan; 146():110366. PubMed ID: 33208242
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles.
    Seo W; Gao Y; He Y; Sun J; Xu H; Feng D; Park SH; Cho YE; Guillot A; Ren T; Wu R; Wang J; Kim SJ; Hwang S; Liangpunsakul S; Yang Y; Niu J; Gao B
    J Hepatol; 2019 Nov; 71(5):1000-1011. PubMed ID: 31279903
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis.
    Jin S; Chen J; Chen L; Histen G; Lin Z; Gross S; Hixon J; Chen Y; Kung C; Chen Y; Fu Y; Lu Y; Lin H; Cai X; Yang H; Cairns RA; Dorsch M; Su SM; Biller S; Mak TW; Cang Y
    Proc Natl Acad Sci U S A; 2015 Jul; 112(29):9088-93. PubMed ID: 26150517
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice.
    Kwon HJ; Won YS; Park O; Chang B; Duryee MJ; Thiele GE; Matsumoto A; Singh S; Abdelmegeed MA; Song BJ; Kawamoto T; Vasiliou V; Thiele GM; Gao B
    Hepatology; 2014 Jul; 60(1):146-57. PubMed ID: 24492981
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characteristics of aldehyde dehydrogenase 2 (Aldh2) knockout mice.
    Yu HS; Oyama T; Isse T; Kitakawa K; Ogawa M; Pham TT; Kawamoto T
    Toxicol Mech Methods; 2009 Nov; 19(9):535-40. PubMed ID: 19874182
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of ALDH2 genotype, PPI treatment and L-cysteine on carcinogenic acetaldehyde in gastric juice and saliva after intragastric alcohol administration.
    Maejima R; Iijima K; Kaihovaara P; Hatta W; Koike T; Imatani A; Shimosegawa T; Salaspuro M
    PLoS One; 2015; 10(4):e0120397. PubMed ID: 25831092
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SLC3A2, as an indirect target gene of ALDH2, exacerbates alcohol-associated liver cancer via the sphingolipid biosynthesis pathway.
    Xia P; Liu DH; Wang D; Wen GM; Zhao ZY
    Free Radic Biol Med; 2023 Sep; 206():125-133. PubMed ID: 37406742
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 6-(Methylsulfinyl)hexyl isothiocyanate protects acetaldehyde-caused cytotoxicity through the induction of aldehyde dehydrogenase in hepatocytes.
    Kitakaze T; Yuan S; Inoue M; Yoshioka Y; Yamashita Y; Ashida H
    Arch Biochem Biophys; 2020 Jun; 686():108329. PubMed ID: 32151565
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protective effects of Alda-1, an ALDH2 activator, on alcohol-derived DNA damage in the esophagus of human ALDH2*2 (Glu504Lys) knock-in mice.
    Hirohashi K; Ohashi S; Amanuma Y; Nakai Y; Ida T; Baba K; Mitani Y; Mizumoto A; Yamamoto Y; Kikuchi O; Matsubara J; Yamada A; Miyamoto S; Seno H; Matsuda T; Muto M
    Carcinogenesis; 2020 Apr; 41(2):194-202. PubMed ID: 31074772
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking.
    Guillot A; Ren T; Jourdan T; Pawlosky RJ; Han E; Kim SJ; Zhang L; Koob GF; Gao B
    Proc Natl Acad Sci U S A; 2019 Dec; 116(51):25974-25981. PubMed ID: 31792171
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacological activation of aldehyde dehydrogenase 2 by Alda-1 reverses alcohol-induced hepatic steatosis and cell death in mice.
    Zhong W; Zhang W; Li Q; Xie G; Sun Q; Sun X; Tan X; Sun X; Jia W; Zhou Z
    J Hepatol; 2015 Jun; 62(6):1375-81. PubMed ID: 25543082
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of acetaldehyde dehydrogenase 2 in the pathogenesis of liver diseases.
    Wu YC; Yao Y; Tao LS; Wang SX; Hu Y; Li LY; Hu S; Meng X; Yang DS; Li H; Xu T
    Cell Signal; 2023 Feb; 102():110550. PubMed ID: 36464104
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aged Garlic Extract Prevents Alcohol-Induced Cytotoxicity through Induction of Aldehyde Dehydrogenase 2 in the Liver of Mice.
    Kitakaze T; Inoue M; Ashida H
    Mol Nutr Food Res; 2023 May; 67(10):e2200627. PubMed ID: 36856009
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium.
    Amanuma Y; Ohashi S; Itatani Y; Tsurumaki M; Matsuda S; Kikuchi O; Nakai Y; Miyamoto S; Oyama T; Kawamoto T; Whelan KA; Nakagawa H; Chiba T; Matsuda T; Muto M
    Sci Rep; 2015 Sep; 5():14142. PubMed ID: 26374466
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Use of an "acetaldehyde clamp" in the determination of low-KM aldehyde dehydrogenase activity in H4-II-E-C3 rat hepatoma cells.
    Moncada C; Fuentes N; Lladser A; Encina G; Sapag A; Karahanian E; Israel Y
    Alcohol; 2003; 31(1-2):19-24. PubMed ID: 14615007
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aldehyde dehydrogenase 2 gene targeting mouse lacking enzyme activity shows high acetaldehyde level in blood, brain, and liver after ethanol gavages.
    Isse T; Matsuno K; Oyama T; Kitagawa K; Kawamoto T
    Alcohol Clin Exp Res; 2005 Nov; 29(11):1959-64. PubMed ID: 16340452
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acetaldehyde and alcoholic cardiomyopathy: lessons from the ADH and ALDH2 transgenic models.
    Ren J
    Novartis Found Symp; 2007; 285():69-76; discussion 76-9, 198-9. PubMed ID: 17590987
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Elevated levels of hemoglobin-associated acetaldehyde related to alcohol drinking in the atypical genotype of low Km aldehyde dehydrogenase.
    Takeshita T; Kawai T; Morimoto K
    Cancer Res; 1997 Apr; 57(7):1241-3. PubMed ID: 9102206
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Diminished alcohol preference in transgenic mice lacking aldehyde dehydrogenase activity.
    Isse T; Oyama T; Kitagawa K; Matsuno K; Matsumoto A; Yoshida A; Nakayama K; Nakayama K; Kawamoto T
    Pharmacogenetics; 2002 Nov; 12(8):621-6. PubMed ID: 12439222
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The murine hepatic sequelae of long-term ethanol consumption are sex-specific and exacerbated by Aldh1b1 loss.
    Müller MF; Kendall TJ; Adams DJ; Zhou Y; Arends MJ
    Exp Mol Pathol; 2018 Aug; 105(1):63-70. PubMed ID: 29859945
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.