BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 33208877)

  • 1. Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screen.
    Schukur L; Zimmermann T; Niewoehner O; Kerr G; Gleim S; Bauer-Probst B; Knapp B; Galli GG; Liang X; Mendiola A; Reece-Hoyes J; Rapti M; Barbosa I; Reschke M; Radimerski T; Thoma CR
    Sci Rep; 2020 Nov; 10(1):20044. PubMed ID: 33208877
    [TBL] [Abstract][Full Text] [Related]  

  • 2.
    Qiao X; Liu Y; Prada ML; Mohan AK; Gupta A; Jaiswal A; Sharma M; Merisaari J; Haikala HM; Talvinen K; Yetukuri L; Pylvänäinen JW; Klefström J; Kronqvist P; Meinander A; Aittokallio T; Hietakangas V; Eilers M; Westermarck J
    Cancer Res; 2020 Apr; 80(7):1414-1427. PubMed ID: 32029551
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin.
    Matsuura K; Huang NJ; Cocce K; Zhang L; Kornbluth S
    Oncogene; 2017 Mar; 36(12):1698-1706. PubMed ID: 27721409
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5.
    Flack JE; Mieszczanek J; Novcic N; Bienz M
    Mol Cell; 2017 Jul; 67(2):181-193.e5. PubMed ID: 28689657
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of myocardin function by the ubiquitin E3 ligase UBR5.
    Hu G; Wang X; Saunders DN; Henderson M; Russell AJ; Herring BP; Zhou J
    J Biol Chem; 2010 Apr; 285(16):11800-9. PubMed ID: 20167605
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The G1 phase E3 ubiquitin ligase TRUSS that gets deregulated in human cancers is a novel substrate of the S-phase E3 ubiquitin ligase Skp2.
    Jamal A; Swarnalatha M; Sultana S; Joshi P; Panda SK; Kumar V
    Cell Cycle; 2015; 14(16):2688-700. PubMed ID: 26038816
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cryo-EM structure of the chain-elongating E3 ubiquitin ligase UBR5.
    Hodáková Z; Grishkovskaya I; Brunner HL; Bolhuis DL; Belačić K; Schleiffer A; Kotisch H; Brown NG; Haselbach D
    EMBO J; 2023 Aug; 42(16):e113348. PubMed ID: 37409633
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia.
    Shearer RF; Frikstad KM; McKenna J; McCloy RA; Deng N; Burgess A; Stokke T; Patzke S; Saunders DN
    Mol Biol Cell; 2018 Jul; 29(13):1542-1554. PubMed ID: 29742019
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity.
    Paul I; Ahmed SF; Bhowmik A; Deb S; Ghosh MK
    Oncogene; 2013 Mar; 32(10):1284-95. PubMed ID: 22543587
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Small molecule Z363 co-regulates TAF10 and MYC via the E3 ligase TRIP12 to suppress tumour growth.
    Xiong Y; Wang L; Xu S; Fu B; Che Y; Zaky MY; Tian R; Yao R; Guo D; Sha Z; Lin F; Lin X; Wu H
    Clin Transl Med; 2023 Jan; 13(1):e1153. PubMed ID: 36639831
    [TBL] [Abstract][Full Text] [Related]  

  • 11. E3 Ubiquitin Ligase UBR5 Drives the Growth and Metastasis of Triple-Negative Breast Cancer.
    Liao L; Song M; Li X; Tang L; Zhang T; Zhang L; Pan Y; Chouchane L; Ma X
    Cancer Res; 2017 Apr; 77(8):2090-2101. PubMed ID: 28330927
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The MLLE domain of the ubiquitin ligase UBR5 binds to its catalytic domain to regulate substrate binding.
    Muñoz-Escobar J; Matta-Camacho E; Kozlov G; Gehring K
    J Biol Chem; 2015 Sep; 290(37):22841-50. PubMed ID: 26224628
    [TBL] [Abstract][Full Text] [Related]  

  • 13. UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy.
    Seaborne RA; Hughes DC; Turner DC; Owens DJ; Baehr LM; Gorski P; Semenova EA; Borisov OV; Larin AK; Popov DV; Generozov EV; Sutherland H; Ahmetov II; Jarvis JC; Bodine SC; Sharples AP
    J Physiol; 2019 Jul; 597(14):3727-3749. PubMed ID: 31093990
    [TBL] [Abstract][Full Text] [Related]  

  • 14. UBR5 Contributes to Colorectal Cancer Progression by Destabilizing the Tumor Suppressor ECRG4.
    Wang J; Zhao X; Jin L; Wu G; Yang Y
    Dig Dis Sci; 2017 Oct; 62(10):2781-2789. PubMed ID: 28856538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target.
    Saurabh K; Shah PP; Doll MA; Siskind LJ; Beverly LJ
    BMC Cancer; 2020 Aug; 20(1):824. PubMed ID: 32867711
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The E3 ligase UBR5 regulates gastric cancer cell growth by destabilizing the tumor suppressor GKN1.
    Yang M; Jiang N; Cao QW; Ma MQ; Sun Q
    Biochem Biophys Res Commun; 2016 Sep; 478(4):1624-9. PubMed ID: 27590582
    [TBL] [Abstract][Full Text] [Related]  

  • 17. E3 ubiquitin ligase UBR5 promotes pancreatic cancer growth and aerobic glycolysis by downregulating FBP1 via destabilization of C/EBPα.
    Chen L; Yuan R; Wen C; Liu T; Feng Q; Deng X; Du Y; Peng X
    Oncogene; 2021 Jan; 40(2):262-276. PubMed ID: 33122826
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of Pirh2 in mediating the regulation of p53 and c-Myc.
    Hakem A; Bohgaki M; Lemmers B; Tai E; Salmena L; Matysiak-Zablocki E; Jung YS; Karaskova J; Kaustov L; Duan S; Madore J; Boutros P; Sheng Y; Chesi M; Bergsagel PL; Perez-Ordonez B; Mes-Masson AM; Penn L; Squire J; Chen X; Jurisica I; Arrowsmith C; Sanchez O; Benchimol S; Hakem R
    PLoS Genet; 2011 Nov; 7(11):e1002360. PubMed ID: 22125490
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inflammation-dependent overexpression of c-Myc enhances CRL4
    Liu H; Lu W; He H; Wu J; Zhang C; Gong H; Yang C
    J Pathol; 2019 Aug; 248(4):464-475. PubMed ID: 30945288
    [TBL] [Abstract][Full Text] [Related]  

  • 20. UBR5 HECT domain mutations identified in mantle cell lymphoma control maturation of B cells.
    Swenson SA; Gilbreath TJ; Vahle H; Hynes-Smith RW; Graham JH; Law HC; Amador C; Woods NT; Green MR; Buckley SM
    Blood; 2020 Jul; 136(3):299-312. PubMed ID: 32325489
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.