BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 33217633)

  • 21. Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
    Romagnoli R; Prencipe F; Oliva P; Kimatrai Salvador M; Brancale A; Ferla S; Hamel E; Viola G; Bortolozzi R; Persoons L; Balzarini J; Liekens S; Schols D
    Bioorg Chem; 2020 Apr; 97():103665. PubMed ID: 32086053
    [TBL] [Abstract][Full Text] [Related]  

  • 22. 1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity.
    Naaz F; Preeti Pallavi MC; Shafi S; Mulakayala N; Shahar Yar M; Sampath Kumar HM
    Bioorg Chem; 2018 Dec; 81():1-20. PubMed ID: 30081353
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT; Shi TQ; Zhu HL; Liu CH
    Bioorg Med Chem; 2019 Feb; 27(3):502-515. PubMed ID: 30606674
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site.
    Li W; Sun H; Xu F; Shuai W; Liu J; Xu S; Yao H; Ma C; Zhu Z; Xu J
    Bioorg Chem; 2019 Apr; 85():49-59. PubMed ID: 30599412
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G; Li C; He L; Lei K; Wang F; Pu Y; Yang Z; Cao D; Ma L; Chen J; Sang Y; Liang X; Xiang M; Peng A; Wei Y; Chen L
    Bioorg Med Chem; 2014 Apr; 22(7):2060-79. PubMed ID: 24629450
    [TBL] [Abstract][Full Text] [Related]  

  • 26. N-Arylsulfonylsubstituted-1H indole derivatives as small molecule dual inhibitors of signal transducer and activator of transcription 3 (STAT3) and tubulin.
    Zhou Q; Zhu J; Chen J; Ji P; Qiao C
    Bioorg Med Chem; 2018 Jan; 26(1):96-106. PubMed ID: 29174507
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies.
    Kumar NP; Thatikonda S; Tokala R; Kumari SS; Lakshmi UJ; Godugu C; Shankaraiah N; Kamal A
    Bioorg Med Chem; 2018 May; 26(8):1996-2008. PubMed ID: 29525336
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ; Li YJ; Jiang AQ; Yang MR; Zhu QZ; Dong H; Zhu HL
    Eur J Med Chem; 2015 Apr; 94():447-57. PubMed ID: 25828827
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Design, synthesis and biological evaluation of indole-based [1,2,4]triazolo[4,3-a] pyridine derivatives as novel microtubule polymerization inhibitors.
    Wu CJ; Wu JQ; Hu Y; Pu S; Lin Y; Zeng Z; Hu J; Chen WH
    Eur J Med Chem; 2021 Nov; 223():113629. PubMed ID: 34175541
    [TBL] [Abstract][Full Text] [Related]  

  • 30. 1,3,4-oxadiazole-2-thione Derivatives; Novel Approach for Anticancer and Tubulin Polymerization Inhibitory Activities.
    Abdel-Aziz M; Metwally KA; Gamal-Eldeen AM; Aly OM
    Anticancer Agents Med Chem; 2015; 16(2):269-77. PubMed ID: 26343141
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design, synthesis, biological evaluation, and molecular docking of new benzofuran and indole derivatives as tubulin polymerization inhibitors.
    El-Sayed NF; El-Hussieny M; Ewies EF; El Shehry MF; Awad HM; Fouad MA
    Drug Dev Res; 2022 Apr; 83(2):485-500. PubMed ID: 34523738
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
    Preti D; Romagnoli R; Rondanin R; Cacciari B; Hamel E; Balzarini J; Liekens S; Schols D; Estévez-Sarmiento F; Quintana J; Estévez F
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1225-1238. PubMed ID: 30141353
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis, anti-cancer evaluation of benzenesulfonamide derivatives as potent tubulin-targeting agents.
    Yang J; Yang S; Zhou S; Lu D; Ji L; Li Z; Yu S; Meng X
    Eur J Med Chem; 2016 Oct; 122():488-496. PubMed ID: 27423028
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design and synthesis of pyrazole-oxindole conjugates targeting tubulin polymerization as new anticancer agents.
    Kamal A; Shaik AB; Jain N; Kishor C; Nagabhushana A; Supriya B; Bharath Kumar G; Chourasiya SS; Suresh Y; Mishra RK; Addlagatta A
    Eur J Med Chem; 2015 Mar; 92():501-13. PubMed ID: 25599948
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors.
    La Regina G; Bai R; Rensen WM; Di Cesare E; Coluccia A; Piscitelli F; Famiglini V; Reggio A; Nalli M; Pelliccia S; Da Pozzo E; Costa B; Granata I; Porta A; Maresca B; Soriani A; Iannitto ML; Santoni A; Li J; Miranda Cona M; Chen F; Ni Y; Brancale A; Dondio G; Vultaggio S; Varasi M; Mercurio C; Martini C; Hamel E; Lavia P; Novellino E; Silvestri R
    J Med Chem; 2013 Jan; 56(1):123-49. PubMed ID: 23214452
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S; An B; Li Y; Luo X; Li X; Jia X
    Bioorg Med Chem Lett; 2018 Jun; 28(10):1769-1775. PubMed ID: 29673981
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Design, synthesis, and biological evaluation of cyclic-indole derivatives as anti-tumor agents via the inhibition of tubulin polymerization.
    Yan J; Hu J; An B; Huang L; Li X
    Eur J Med Chem; 2017 Jan; 125():663-675. PubMed ID: 27721152
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structure modification and biological evaluation of indole-chalcone derivatives as anti-tumor agents through dual targeting tubulin and TrxR.
    Yan J; Xu Y; Jin X; Zhang Q; Ouyang F; Han L; Zhan M; Li X; Liang B; Huang X
    Eur J Med Chem; 2022 Jan; 227():113897. PubMed ID: 34649064
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Synthesis, biological evaluation, and molecular docking studies of novel 1-benzene acyl-2-(1-methylindol-3-yl)-benzimidazole derivatives as potential tubulin polymerization inhibitors.
    Wang YT; Qin YJ; Yang N; Zhang YL; Liu CH; Zhu HL
    Eur J Med Chem; 2015 Jun; 99():125-37. PubMed ID: 26070164
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
    Pang Y; Lin H; Ou C; Cao Y; An B; Yan J; Li X
    Eur J Med Chem; 2019 Nov; 182():111670. PubMed ID: 31499359
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.