BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 33220403)

  • 1. High folic acid intake increases methylation-dependent expression of Lsr and dysregulates hepatic cholesterol homeostasis.
    Leclerc D; Jelinek J; Christensen KE; Issa JJ; Rozen R
    J Nutr Biochem; 2021 Feb; 88():108554. PubMed ID: 33220403
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.
    Christensen KE; Mikael LG; Leung KY; Lévesque N; Deng L; Wu Q; Malysheva OV; Best A; Caudill MA; Greene ND; Rozen R
    Am J Clin Nutr; 2015 Mar; 101(3):646-58. PubMed ID: 25733650
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Testicular MTHFR deficiency may explain sperm DNA hypomethylation associated with high dose folic acid supplementation.
    Aarabi M; Christensen KE; Chan D; Leclerc D; Landry M; Ly L; Rozen R; Trasler J
    Hum Mol Genet; 2018 Apr; 27(7):1123-1135. PubMed ID: 29360980
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
    Mikael LG; Pancer J; Jiang X; Wu Q; Caudill M; Rozen R
    Mol Nutr Food Res; 2013 Apr; 57(4):661-70. PubMed ID: 23112124
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency.
    Bahous RH; Cosín-Tomás M; Deng L; Leclerc D; Malysheva O; Ho MK; Pallàs M; Kaliman P; Bedell BJ; Caudill MA; Rozen R
    Mol Neurobiol; 2019 Jun; 56(6):4175-4191. PubMed ID: 30288696
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Moderate Folic Acid Supplementation in Pregnant Mice Results in Altered Methyl Metabolism and in Sex-Specific Placental Transcription Changes.
    Luan Y; Leclerc D; Cosín-Tomás M; Malysheva OV; Wasek B; Bottiglieri T; Caudill MA; Rozen R
    Mol Nutr Food Res; 2021 Jul; 65(14):e2100197. PubMed ID: 34010503
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sperm DNA methylation defects in a new mouse model of the 5,10-methylenetetrahydrofolate reductase 677C>T variant and correction with moderate dose folic acid supplementation.
    Martínez Duncker Rebolledo E; Chan D; Christensen KE; Reagan AM; Howell GR; Rozen R; Trasler J
    Mol Hum Reprod; 2024 Mar; 30(4):. PubMed ID: 38366926
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.
    Bahous RH; Jadavji NM; Deng L; Cosín-Tomás M; Lu J; Malysheva O; Leung KY; Ho MK; Pallàs M; Kaliman P; Greene NDE; Bedell BJ; Caudill MA; Rozen R
    Hum Mol Genet; 2017 Mar; 26(5):888-900. PubMed ID: 28069796
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.
    Christensen KE; Wu Q; Wang X; Deng L; Caudill MA; Rozen R
    J Nutr; 2010 Oct; 140(10):1736-41. PubMed ID: 20724492
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice.
    Chew TW; Jiang X; Yan J; Wang W; Lusa AL; Carrier BJ; West AA; Malysheva OV; Brenna JT; Gregory JF; Caudill MA
    J Nutr; 2011 Aug; 141(8):1475-81. PubMed ID: 21697299
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitory action of benzo[α]pyrene on hepatic lipoprotein receptors in vitro and on liver lipid homeostasis in mice.
    Layeghkhavidaki H; Lanhers MC; Akbar S; Gregory-Pauron L; Oster T; Grova N; Appenzeller B; Jasniewski J; Feidt C; Corbier C; Yen FT
    PLoS One; 2014; 9(7):e102991. PubMed ID: 25054229
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acute high folic acid treatment in SH-SY5Y cells with and without MTHFR function leads to gene expression changes in epigenetic modifying enzymes, changes in epigenetic marks, and changes in dendritic spine densities.
    Clark DF; Schmelz R; Rogers N; Smith NE; Shorter KR
    PLoS One; 2021; 16(1):e0245005. PubMed ID: 33411826
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.
    Lawrance AK; Deng L; Rozen R
    Gut; 2009 Jun; 58(6):805-11. PubMed ID: 19174418
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disturbed one-carbon metabolism causing adverse reproductive outcomes in mice is associated with altered expression of apolipoprotein AI and inflammatory mediators PPARα, interferon-γ, and interleukin-10.
    Mikael LG; Pancer J; Wu Q; Rozen R
    J Nutr; 2012 Mar; 142(3):411-8. PubMed ID: 22259189
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression profile of hepatic genes related to lipid homeostasis in LSR heterozygous mice contributes to their increased response to high-fat diet.
    Akbar S; Pinçon A; Lanhers MC; Claudepierre T; Corbier C; Gregory-Pauron L; Malaplate-Armand C; Visvikis A; Oster T; Yen FT
    Physiol Genomics; 2016 Dec; 48(12):928-935. PubMed ID: 27789735
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stability of DNA methylation patterns in mouse spermatogonia under conditions of MTHFR deficiency and methionine supplementation.
    Garner JL; Niles KM; McGraw S; Yeh JR; Cushnie DW; Hermo L; Nagano MC; Trasler JM
    Biol Reprod; 2013 Nov; 89(5):125. PubMed ID: 24048573
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice.
    Leclerc D; Cao Y; Deng L; Mikael LG; Wu Q; Rozen R
    Mol Nutr Food Res; 2013 Apr; 57(4):686-97. PubMed ID: 23001810
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Association of Folate and Vitamins Involved in the 1-Carbon Cycle with Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) and Global DNA Methylation in Patients with Colorectal Cancer.
    Ferrari A; Torrezan GT; Carraro DM; Aguiar Junior S
    Nutrients; 2019 Jun; 11(6):. PubMed ID: 31216671
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Supplemental dietary folic acid has no effect on chromosome damage in erythrocyte progenitor cells of mice.
    Swayne BG; Behan NA; Williams A; Stover PJ; Yauk CL; MacFarlane AJ
    J Nutr; 2012 May; 142(5):813-7. PubMed ID: 22437555
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stability of the human sperm DNA methylome to folic acid fortification and short-term supplementation.
    Chan D; McGraw S; Klein K; Wallock LM; Konermann C; Plass C; Chan P; Robaire B; Jacob RA; Greenwood CM; Trasler JM
    Hum Reprod; 2017 Feb; 32(2):272-283. PubMed ID: 27994001
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.