These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 33226150)

  • 21. Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction.
    Tokala R; Mahajan S; Kiranmai G; Sigalapalli DK; Sana S; John SE; Nagesh N; Shankaraiah N
    Bioorg Chem; 2021 Jan; 106():104481. PubMed ID: 33261848
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Substituted 2-arylquinazolinones: Design, synthesis, and evaluation of cytotoxicity and inhibition of topoisomerases.
    Khadka DB; Tran GH; Shin S; Nguyen HT; Cao HT; Zhao C; Jin Y; Van HT; Chau MV; Kwon Y; Le TN; Cho WJ
    Eur J Med Chem; 2015 Oct; 103():69-79. PubMed ID: 26334499
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
    Zhuo ST; Li CY; Hu MH; Chen SB; Yao PF; Huang SL; Ou TM; Tan JH; An LK; Li D; Gu LQ; Huang ZS
    Org Biomol Chem; 2013 Jun; 11(24):3989-4005. PubMed ID: 23657605
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Design and novel synthetic approach supported with molecular docking and biological evidence for naphthoquinone-hydrazinotriazolothiadiazine analogs as potential anticancer inhibiting topoisomerase-IIB.
    Mohamady S; Gibriel AA; Ahmed MS; Hendy MS; Naguib BH
    Bioorg Chem; 2020 Mar; 96():103641. PubMed ID: 32032844
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Pyridazino[1,6-b]quinazolinones as new anticancer scaffold: Synthesis, DNA intercalation, topoisomerase I inhibition and antitumor evaluation in vitro and in vivo.
    Huang WY; Zhang XR; Lyu L; Wang SQ; Zhang XT
    Bioorg Chem; 2020 Jun; 99():103814. PubMed ID: 32278208
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Synthesis and evaluation of (18)F-labeled ATP competitive inhibitors of topoisomerase II as probes for imaging topoisomerase II expression.
    Daumar P; Zeglis BM; Ramos N; Divilov V; Sevak KK; Pillarsetty N; Lewis JS
    Eur J Med Chem; 2014 Oct; 86():769-81. PubMed ID: 25240701
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Design, molecular modeling and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as inhibitors of topoisomerase II.
    El-Metwally SA; Khalil AK; El-Sayed WM
    Bioorg Chem; 2020 Jan; 94():103492. PubMed ID: 31864673
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Triazoloquinoxalines-based DNA intercalators-Topo II inhibitors: design, synthesis, docking, ADMET and anti-proliferative evaluations.
    Elwan A; Sakr H; El-Helby AA; El-Morsy A; Abdelgawad MA; Ghoneim MM; El-Sherbiny M; El-Adl K
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):1556-1567. PubMed ID: 35635148
    [TBL] [Abstract][Full Text] [Related]  

  • 29. New bis([1,2,4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer evaluation.
    Alanazi MM; Mahdy HA; Alsaif NA; Obaidullah AJ; Alkahtani HM; Al-Mehizia AA; Alsubaie SM; Dahab MA; Eissa IH
    Bioorg Chem; 2021 Jul; 112():104949. PubMed ID: 34023640
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis and in vitro cytotoxicity evaluation of β-carboline-combretastatin carboxamides as apoptosis inducing agents: DNA intercalation and topoisomerase-II inhibition.
    Jadala C; Sathish M; Reddy TS; Reddy VG; Tokala R; Bhargava SK; Shankaraiah N; Nagesh N; Kamal A
    Bioorg Med Chem; 2019 Aug; 27(15):3285-3298. PubMed ID: 31227365
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors.
    Zhou DC; Lu YT; Mai YW; Zhang C; Xia J; Yao PF; Wang HG; Huang SL; Huang ZS
    Bioorg Chem; 2019 Oct; 91():103131. PubMed ID: 31377387
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme.
    El-Helby AA; Sakr H; Ayyad RRA; El-Adl K; Ali MM; Khedr F
    Anticancer Agents Med Chem; 2018; 18(8):1184-1196. PubMed ID: 29651967
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Novel nalidixic acid derivatives targeting topoisomerase II enzyme; Design, synthesis, anticancer activity and effect on cell cycle profile.
    Khalil OM; Gedawy EM; El-Malah AA; Adly ME
    Bioorg Chem; 2019 Mar; 83():262-276. PubMed ID: 30391699
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis of carbazole derivatives containing chalcone analogs as non-intercalative topoisomerase II catalytic inhibitors and apoptosis inducers.
    Li PH; Jiang H; Zhang WJ; Li YL; Zhao MC; Zhou W; Zhang LY; Tang YD; Dong CZ; Huang ZS; Chen HX; Du ZY
    Eur J Med Chem; 2018 Feb; 145():498-510. PubMed ID: 29335211
    [TBL] [Abstract][Full Text] [Related]  

  • 35. New fused pyrimidine derivatives with anticancer activity: Synthesis, topoisomerase II inhibition, apoptotic inducing activity and molecular modeling study.
    Nemr MTM; AboulMagd AM
    Bioorg Chem; 2020 Oct; 103():104134. PubMed ID: 32750610
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity.
    Tokala R; Sana S; Lakshmi UJ; Sankarana P; Sigalapalli DK; Gadewal N; Kode J; Shankaraiah N
    Bioorg Chem; 2020 Dec; 105():104357. PubMed ID: 33091673
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Anticancer Activity and Topoisomerase II Inhibition of Naphthalimides with ω-Hydroxylalkylamine Side-Chains of Different Lengths.
    Tomczyk MD; Byczek-Wyrostek A; Strama K; Wawszków M; Kasprzycki P; Walczak KZ
    Med Chem; 2019; 15(5):550-560. PubMed ID: 30207241
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents.
    Thapa P; Kadayat TM; Park S; Shin S; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Bioorg Chem; 2016 Jun; 66():145-59. PubMed ID: 27174797
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.
    Zhang W; Zhang B; Zhang W; Yang T; Wang N; Gao C; Tan C; Liu H; Jiang Y
    Eur J Med Chem; 2016 Jun; 116():59-70. PubMed ID: 27060757
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs).
    Wang X; Chen Z; Tong L; Tan S; Zhou W; Peng T; Han K; Ding J; Xie H; Xu Y
    Eur J Med Chem; 2013 Jul; 65():477-86. PubMed ID: 23770449
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.