These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 33227819)

  • 1. A natural DNMT1 mutation elevates the fetal hemoglobin level via epigenetic derepression of the γ-globin gene in β-thalassemia.
    Gong Y; Zhang X; Zhang Q; Zhang Y; Ye Y; Yu W; Shao C; Yan T; Huang J; Zhong J; Wang L; Li Y; Wang L; Xu X
    Blood; 2021 Mar; 137(12):1652-1657. PubMed ID: 33227819
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.
    Bao X; Zhang X; Wang L; Wang Z; Huang J; Zhang Q; Ye Y; Liu Y; Chen D; Zuo Y; Liu Q; Xu P; Huang B; Fang J; Lao J; Feng X; Li Y; Kurita R; Nakamura Y; Yu W; Ju C; Huang C; Mohandas N; Li D; Zhao C; Xu X
    Am J Hum Genet; 2021 Apr; 108(4):709-721. PubMed ID: 33735615
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
    Ravi NS; Wienert B; Wyman SK; Bell HW; George A; Mahalingam G; Vu JT; Prasad K; Bandlamudi BP; Devaraju N; Rajendiran V; Syedbasha N; Pai AA; Nakamura Y; Kurita R; Narayanasamy M; Balasubramanian P; Thangavel S; Marepally S; Velayudhan SR; Srivastava A; DeWitt MA; Crossley M; Corn JE; Mohankumar KM
    Elife; 2022 Feb; 11():. PubMed ID: 35147495
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA methylation patterns of β-globin cluster in β-thalassemia patients.
    Bao X; Zuo Y; Chen D; Zhao C
    Clin Epigenetics; 2020 Dec; 12(1):187. PubMed ID: 33272312
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
    Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
    Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A natural regulatory mutation in the proximal promoter elevates fetal
    Martyn GE; Wienert B; Kurita R; Nakamura Y; Quinlan KGR; Crossley M
    Blood; 2019 Feb; 133(8):852-856. PubMed ID: 30617196
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
    Roosjen M; McColl B; Kao B; Gearing LJ; Blewitt ME; Vadolas J
    FASEB J; 2014 Apr; 28(4):1610-20. PubMed ID: 24371119
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping.
    Krivega I; Byrnes C; de Vasconcellos JF; Lee YT; Kaushal M; Dean A; Miller JL
    Blood; 2015 Jul; 126(5):665-72. PubMed ID: 25979948
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.
    Martyn GE; Wienert B; Yang L; Shah M; Norton LJ; Burdach J; Kurita R; Nakamura Y; Pearson RCM; Funnell APW; Quinlan KGR; Crossley M
    Nat Genet; 2018 Apr; 50(4):498-503. PubMed ID: 29610478
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.
    Wilber A; Hargrove PW; Kim YS; Riberdy JM; Sankaran VG; Papanikolaou E; Georgomanoli M; Anagnou NP; Orkin SH; Nienhuis AW; Persons DA
    Blood; 2011 Mar; 117(10):2817-26. PubMed ID: 21156846
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BCL11A-targeted γ-globin gene induction by triterpenoid glycosides of Fagonia indica: A preclinical scientific validation of indigenous herb for the treatment of β-hemoglobinopathies.
    Iftikhar F; Khan MBN; Tehreem S; Kanwal N; Musharraf SG
    Bioorg Chem; 2023 Nov; 140():106768. PubMed ID: 37586133
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An Aγ-globin G->A gene polymorphism associated with β
    Breveglieri G; Bianchi N; Cosenza LC; Gamberini MR; Chiavilli F; Zuccato C; Montagner G; Borgatti M; Lampronti I; Finotti A; Gambari R
    BMC Med Genet; 2017 Aug; 18(1):93. PubMed ID: 28851297
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease.
    Khosravi MA; Abbasalipour M; Concordet JP; Berg JV; Zeinali S; Arashkia A; Azadmanesh K; Buch T; Karimipoor M
    Eur J Pharmacol; 2019 Jul; 854():398-405. PubMed ID: 31039344
    [TBL] [Abstract][Full Text] [Related]  

  • 14. miR-30a regulates γ-globin expression in erythoid precursors of intermedia thalassemia through targeting BCL11A.
    Gholampour MA; Asadi M; Naderi M; Azarkeivan A; Soleimani M; Atashi A
    Mol Biol Rep; 2020 May; 47(5):3909-3918. PubMed ID: 32406020
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
    Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
    Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Plastrum testudinis induces γ-globin gene expression through epigenetic histone modifications within the γ-globin gene promoter via activation of the p38 MAPK signaling pathway.
    Qian X; Chen J; Zhao D; Guo L; Qian X
    Int J Mol Med; 2013 Jun; 31(6):1418-28. PubMed ID: 23588991
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β0-Thalassemia Families with High Fetal Hemoglobin Levels.
    Bianchi N; Cosenza LC; Lampronti I; Finotti A; Breveglieri G; Zuccato C; Fabbri E; Marzaro G; Chilin A; De Angelis G; Borgatti M; Gallucci C; Alfieri C; Ribersani M; Isgrò A; Marziali M; Gaziev J; Morrone A; Sodani P; Lucarelli G; Gambari R; Paciaroni K
    Mol Diagn Ther; 2016 Apr; 20(2):161-73. PubMed ID: 26897028
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CRISPR/Cas9-based multiplex genome editing of BCL11A and HBG efficiently induces fetal hemoglobin expression.
    Han Y; Tan X; Jin T; Zhao S; Hu L; Zhang W; Kurita R; Nakamura Y; Liu J; Li D; Zhang Z; Fang X; Huang S
    Eur J Pharmacol; 2022 Mar; 918():174788. PubMed ID: 35093321
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TEA domain transcription factor 4 modulates repression of fetal haemoglobin by direct binding to the γ-globin gene promoters.
    Lin J; Ye Y; Shang X; Zhang Y; Wei X; Xu X
    Br J Haematol; 2021 Dec; 195(5):764-769. PubMed ID: 34569056
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synergistic effect of two β globin gene cluster mutations leading to the hereditary persistence of fetal hemoglobin (HPFH) phenotype.
    Hariharan P; Sawant M; Gorivale M; Manchanda R; Colah R; Ghosh K; Nadkarni A
    Mol Biol Rep; 2017 Oct; 44(5):413-417. PubMed ID: 28879539
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.