284 related articles for article (PubMed ID: 33227819)
1. A natural DNMT1 mutation elevates the fetal hemoglobin level via epigenetic derepression of the γ-globin gene in β-thalassemia.
Gong Y; Zhang X; Zhang Q; Zhang Y; Ye Y; Yu W; Shao C; Yan T; Huang J; Zhong J; Wang L; Li Y; Wang L; Xu X
Blood; 2021 Mar; 137(12):1652-1657. PubMed ID: 33227819
[TBL] [Abstract][Full Text] [Related]
2. Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.
Bao X; Zhang X; Wang L; Wang Z; Huang J; Zhang Q; Ye Y; Liu Y; Chen D; Zuo Y; Liu Q; Xu P; Huang B; Fang J; Lao J; Feng X; Li Y; Kurita R; Nakamura Y; Yu W; Ju C; Huang C; Mohandas N; Li D; Zhao C; Xu X
Am J Hum Genet; 2021 Apr; 108(4):709-721. PubMed ID: 33735615
[TBL] [Abstract][Full Text] [Related]
3. Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
Ravi NS; Wienert B; Wyman SK; Bell HW; George A; Mahalingam G; Vu JT; Prasad K; Bandlamudi BP; Devaraju N; Rajendiran V; Syedbasha N; Pai AA; Nakamura Y; Kurita R; Narayanasamy M; Balasubramanian P; Thangavel S; Marepally S; Velayudhan SR; Srivastava A; DeWitt MA; Crossley M; Corn JE; Mohankumar KM
Elife; 2022 Feb; 11():. PubMed ID: 35147495
[TBL] [Abstract][Full Text] [Related]
4. DNA methylation patterns of β-globin cluster in β-thalassemia patients.
Bao X; Zuo Y; Chen D; Zhao C
Clin Epigenetics; 2020 Dec; 12(1):187. PubMed ID: 33272312
[TBL] [Abstract][Full Text] [Related]
5. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
[TBL] [Abstract][Full Text] [Related]
6. A natural regulatory mutation in the proximal promoter elevates fetal
Martyn GE; Wienert B; Kurita R; Nakamura Y; Quinlan KGR; Crossley M
Blood; 2019 Feb; 133(8):852-856. PubMed ID: 30617196
[TBL] [Abstract][Full Text] [Related]
7. Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
Roosjen M; McColl B; Kao B; Gearing LJ; Blewitt ME; Vadolas J
FASEB J; 2014 Apr; 28(4):1610-20. PubMed ID: 24371119
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping.
Krivega I; Byrnes C; de Vasconcellos JF; Lee YT; Kaushal M; Dean A; Miller JL
Blood; 2015 Jul; 126(5):665-72. PubMed ID: 25979948
[TBL] [Abstract][Full Text] [Related]
9. Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.
Martyn GE; Wienert B; Yang L; Shah M; Norton LJ; Burdach J; Kurita R; Nakamura Y; Pearson RCM; Funnell APW; Quinlan KGR; Crossley M
Nat Genet; 2018 Apr; 50(4):498-503. PubMed ID: 29610478
[TBL] [Abstract][Full Text] [Related]
10. Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.
Wilber A; Hargrove PW; Kim YS; Riberdy JM; Sankaran VG; Papanikolaou E; Georgomanoli M; Anagnou NP; Orkin SH; Nienhuis AW; Persons DA
Blood; 2011 Mar; 117(10):2817-26. PubMed ID: 21156846
[TBL] [Abstract][Full Text] [Related]
11. BCL11A-targeted γ-globin gene induction by triterpenoid glycosides of Fagonia indica: A preclinical scientific validation of indigenous herb for the treatment of β-hemoglobinopathies.
Iftikhar F; Khan MBN; Tehreem S; Kanwal N; Musharraf SG
Bioorg Chem; 2023 Nov; 140():106768. PubMed ID: 37586133
[TBL] [Abstract][Full Text] [Related]
12. An Aγ-globin G->A gene polymorphism associated with β
Breveglieri G; Bianchi N; Cosenza LC; Gamberini MR; Chiavilli F; Zuccato C; Montagner G; Borgatti M; Lampronti I; Finotti A; Gambari R
BMC Med Genet; 2017 Aug; 18(1):93. PubMed ID: 28851297
[TBL] [Abstract][Full Text] [Related]
13. Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease.
Khosravi MA; Abbasalipour M; Concordet JP; Berg JV; Zeinali S; Arashkia A; Azadmanesh K; Buch T; Karimipoor M
Eur J Pharmacol; 2019 Jul; 854():398-405. PubMed ID: 31039344
[TBL] [Abstract][Full Text] [Related]
14. miR-30a regulates γ-globin expression in erythoid precursors of intermedia thalassemia through targeting BCL11A.
Gholampour MA; Asadi M; Naderi M; Azarkeivan A; Soleimani M; Atashi A
Mol Biol Rep; 2020 May; 47(5):3909-3918. PubMed ID: 32406020
[TBL] [Abstract][Full Text] [Related]
15. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
[TBL] [Abstract][Full Text] [Related]
16. Plastrum testudinis induces γ-globin gene expression through epigenetic histone modifications within the γ-globin gene promoter via activation of the p38 MAPK signaling pathway.
Qian X; Chen J; Zhao D; Guo L; Qian X
Int J Mol Med; 2013 Jun; 31(6):1418-28. PubMed ID: 23588991
[TBL] [Abstract][Full Text] [Related]
17. Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β0-Thalassemia Families with High Fetal Hemoglobin Levels.
Bianchi N; Cosenza LC; Lampronti I; Finotti A; Breveglieri G; Zuccato C; Fabbri E; Marzaro G; Chilin A; De Angelis G; Borgatti M; Gallucci C; Alfieri C; Ribersani M; Isgrò A; Marziali M; Gaziev J; Morrone A; Sodani P; Lucarelli G; Gambari R; Paciaroni K
Mol Diagn Ther; 2016 Apr; 20(2):161-73. PubMed ID: 26897028
[TBL] [Abstract][Full Text] [Related]
18. CRISPR/Cas9-based multiplex genome editing of BCL11A and HBG efficiently induces fetal hemoglobin expression.
Han Y; Tan X; Jin T; Zhao S; Hu L; Zhang W; Kurita R; Nakamura Y; Liu J; Li D; Zhang Z; Fang X; Huang S
Eur J Pharmacol; 2022 Mar; 918():174788. PubMed ID: 35093321
[TBL] [Abstract][Full Text] [Related]
19. TEA domain transcription factor 4 modulates repression of fetal haemoglobin by direct binding to the γ-globin gene promoters.
Lin J; Ye Y; Shang X; Zhang Y; Wei X; Xu X
Br J Haematol; 2021 Dec; 195(5):764-769. PubMed ID: 34569056
[TBL] [Abstract][Full Text] [Related]
20. Synergistic effect of two β globin gene cluster mutations leading to the hereditary persistence of fetal hemoglobin (HPFH) phenotype.
Hariharan P; Sawant M; Gorivale M; Manchanda R; Colah R; Ghosh K; Nadkarni A
Mol Biol Rep; 2017 Oct; 44(5):413-417. PubMed ID: 28879539
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
