2506 related articles for article (PubMed ID: 33229547)
1. Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis.
Yi J; Zhu J; Wu J; Thompson CB; Jiang X
Proc Natl Acad Sci U S A; 2020 Dec; 117(49):31189-31197. PubMed ID: 33229547
[TBL] [Abstract][Full Text] [Related]
2. Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids
Liu G; Kuang S; Cao R; Wang J; Peng Q; Sun C
FASEB J; 2019 Sep; 33(9):10089-10103. PubMed ID: 31199678
[TBL] [Abstract][Full Text] [Related]
3. Aspirin promotes RSL3-induced ferroptosis by suppressing mTOR/SREBP-1/SCD1-mediated lipogenesis in PIK3CA-mutant colorectal cancer.
Chen H; Qi Q; Wu N; Wang Y; Feng Q; Jin R; Jiang L
Redox Biol; 2022 Sep; 55():102426. PubMed ID: 35963119
[TBL] [Abstract][Full Text] [Related]
4. TGF-β1 promotes SCD1 expression via the PI3K-Akt-mTOR-SREBP1 signaling pathway in lung fibroblasts.
Zhou Z; Liang S; Zhou Z; Liu J; Zhang J; Meng X; Zou F; Zhao H; Yu C; Cai S
Respir Res; 2023 Jan; 24(1):8. PubMed ID: 36627645
[TBL] [Abstract][Full Text] [Related]
5. FGFR3 stimulates stearoyl CoA desaturase 1 activity to promote bladder tumor growth.
Du X; Wang QR; Chan E; Merchant M; Liu J; French D; Ashkenazi A; Qing J
Cancer Res; 2012 Nov; 72(22):5843-55. PubMed ID: 23019225
[TBL] [Abstract][Full Text] [Related]
6. G protein-coupled estrogen receptor activates PI3K/AKT/mTOR signaling to suppress ferroptosis via SREBP1/SCD1-mediated lipogenesis.
Chen J; Zhao R; Wang Y; Xiao H; Lin W; Diao M; He S; Mei P; Liao Y
Mol Med; 2024 Feb; 30(1):28. PubMed ID: 38383297
[TBL] [Abstract][Full Text] [Related]
7. Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway.
Tan SH; Shui G; Zhou J; Shi Y; Huang J; Xia D; Wenk MR; Shen HM
Autophagy; 2014 Feb; 10(2):226-42. PubMed ID: 24296537
[TBL] [Abstract][Full Text] [Related]
8. Oleate activates SREBP-1 signaling activity in
Lounis MA; Bergeron KF; Burhans MS; Ntambi JM; Mounier C
Am J Physiol Endocrinol Metab; 2017 Dec; 313(6):E710-E720. PubMed ID: 28851735
[TBL] [Abstract][Full Text] [Related]
9. Positive feedback loop between PI3K-Akt-mTORC1 signaling and the lipogenic pathway boosts Akt signaling: induction of the lipogenic pathway by a melanoma antigen.
Yamauchi Y; Furukawa K; Hamamura K; Furukawa K
Cancer Res; 2011 Jul; 71(14):4989-97. PubMed ID: 21632551
[TBL] [Abstract][Full Text] [Related]
10. MC-LR Aggravates Liver Lipid Metabolism Disorders in Obese Mice Fed a High-Fat Diet via PI3K/AKT/mTOR/SREBP1 Signaling Pathway.
Chu H; Du C; Yang Y; Feng X; Zhu L; Chen J; Yang F
Toxins (Basel); 2022 Nov; 14(12):. PubMed ID: 36548730
[TBL] [Abstract][Full Text] [Related]
11. Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.
Calvisi DF; Wang C; Ho C; Ladu S; Lee SA; Mattu S; Destefanis G; Delogu S; Zimmermann A; Ericsson J; Brozzetti S; Staniscia T; Chen X; Dombrowski F; Evert M
Gastroenterology; 2011 Mar; 140(3):1071-83. PubMed ID: 21147110
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of PI3K-AKT-mTOR pathway sensitizes endometrial cancer cell lines to PARP inhibitors.
Philip CA; Laskov I; Beauchamp MC; Marques M; Amin O; Bitharas J; Kessous R; Kogan L; Baloch T; Gotlieb WH; Yasmeen A
BMC Cancer; 2017 Sep; 17(1):638. PubMed ID: 28886696
[TBL] [Abstract][Full Text] [Related]
13. PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis.
Xu W; Yang Z; Xie C; Zhu Y; Shu X; Zhang Z; Li N; Chai N; Zhang S; Wu K; Nie Y; Lu N
J Exp Clin Cancer Res; 2018 Aug; 37(1):198. PubMed ID: 30134988
[TBL] [Abstract][Full Text] [Related]
14. Activation of sterol regulatory element-binding protein 1 (SREBP1)-mediated lipogenesis by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma.
Lo AK; Lung RW; Dawson CW; Young LS; Ko CW; Yeung WW; Kang W; To KF; Lo KW
J Pathol; 2018 Oct; 246(2):180-190. PubMed ID: 29968360
[TBL] [Abstract][Full Text] [Related]
15. Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP.
Ricoult SJ; Yecies JL; Ben-Sahra I; Manning BD
Oncogene; 2016 Mar; 35(10):1250-60. PubMed ID: 26028026
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of mTOR complex 2 induces GSK3/FBXW7-dependent degradation of sterol regulatory element-binding protein 1 (SREBP1) and suppresses lipogenesis in cancer cells.
Li S; Oh YT; Yue P; Khuri FR; Sun SY
Oncogene; 2016 Feb; 35(5):642-50. PubMed ID: 25893295
[TBL] [Abstract][Full Text] [Related]
17. Discrete signaling mechanisms of mTORC1 and mTORC2: Connected yet apart in cellular and molecular aspects.
Jhanwar-Uniyal M; Amin AG; Cooper JB; Das K; Schmidt MH; Murali R
Adv Biol Regul; 2017 May; 64():39-48. PubMed ID: 28189457
[TBL] [Abstract][Full Text] [Related]
18. Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.
Martelli AM; Evangelisti C; Chappell W; Abrams SL; Bäsecke J; Stivala F; Donia M; Fagone P; Nicoletti F; Libra M; Ruvolo V; Ruvolo P; Kempf CR; Steelman LS; McCubrey JA
Leukemia; 2011 Jul; 25(7):1064-79. PubMed ID: 21436840
[TBL] [Abstract][Full Text] [Related]
19. Caffeic acid phenethyl ester reverses doxorubicin resistance in breast cancer cells via lipid metabolism regulation at least partly by suppressing the Akt/mTOR/SREBP1 pathway.
Liang LC; Zhao L; Yu B; Hu HX; He XH; Zhang YM
Kaohsiung J Med Sci; 2023 Jun; 39(6):605-615. PubMed ID: 36960852
[TBL] [Abstract][Full Text] [Related]
20. Akt Serine/Threonine Kinase 1 Regulates de Novo Fatty Acid Synthesis through the Mammalian Target of Rapamycin/Sterol Regulatory Element Binding Protein 1 Axis in Dairy Goat Mammary Epithelial Cells.
Zhang T; Huang J; Yi Y; Zhang X; Loor JJ; Cao Y; Shi H; Luo J
J Agric Food Chem; 2018 Feb; 66(5):1197-1205. PubMed ID: 29323924
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
