254 related articles for article (PubMed ID: 33230162)
1. Small molecule modulation of the p75 neurotrophin receptor inhibits multiple amyloid beta-induced tau pathologies.
Yang T; Tran KC; Zeng AY; Massa SM; Longo FM
Sci Rep; 2020 Nov; 10(1):20322. PubMed ID: 33230162
[TBL] [Abstract][Full Text] [Related]
2. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinal vascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway.
Elshaer SL; Alwhaibi A; Mohamed R; Lemtalsi T; Coucha M; Longo FM; El-Remessy AB
Diabetologia; 2019 Aug; 62(8):1488-1500. PubMed ID: 31073629
[TBL] [Abstract][Full Text] [Related]
3. Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic mice.
Nguyen TV; Shen L; Vander Griend L; Quach LN; Belichenko NP; Saw N; Yang T; Shamloo M; Wyss-Coray T; Massa SM; Longo FM
J Alzheimers Dis; 2014; 42(2):459-83. PubMed ID: 24898660
[TBL] [Abstract][Full Text] [Related]
4. Small-molecule modulation of the p75 neurotrophin receptor inhibits a wide range of tau molecular pathologies and their sequelae in P301S tauopathy mice.
Yang T; Liu H; Tran KC; Leng A; Massa SM; Longo FM
Acta Neuropathol Commun; 2020 Sep; 8(1):156. PubMed ID: 32891185
[TBL] [Abstract][Full Text] [Related]
5. Small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model.
Knowles JK; Simmons DA; Nguyen TV; Vander Griend L; Xie Y; Zhang H; Yang T; Pollak J; Chang T; Arancio O; Buckwalter MS; Wyss-Coray T; Massa SM; Longo FM
Neurobiol Aging; 2013 Aug; 34(8):2052-63. PubMed ID: 23545424
[TBL] [Abstract][Full Text] [Related]
6. Amelioration of cisplatin-induced experimental peripheral neuropathy by a small molecule targeting p75 NTR.
Friesland A; Weng Z; Duenas M; Massa SM; Longo FM; Lu Q
Neurotoxicology; 2014 Dec; 45():81-90. PubMed ID: 25277379
[TBL] [Abstract][Full Text] [Related]
7. Small molecule modulation of the p75 neurotrophin receptor suppresses age- and genotype-associated neurodegeneration in HIV gp120 transgenic mice.
Xie Y; Seawell J; Boesch E; Allen L; Suchy A; Longo FM; Meeker RB
Exp Neurol; 2021 Jan; 335():113489. PubMed ID: 33007293
[TBL] [Abstract][Full Text] [Related]
8. A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.
Simmons DA; Knowles JK; Belichenko NP; Banerjee G; Finkle C; Massa SM; Longo FM
PLoS One; 2014; 9(8):e102136. PubMed ID: 25153701
[TBL] [Abstract][Full Text] [Related]
9. Neurotrophin receptor p75 mediates amyloid β-induced tau pathology.
Shen LL; Li WW; Xu YL; Gao SH; Xu MY; Bu XL; Liu YH; Wang J; Zhu J; Zeng F; Yao XQ; Gao CY; Xu ZQ; Zhou XF; Wang YJ
Neurobiol Dis; 2019 Dec; 132():104567. PubMed ID: 31394202
[TBL] [Abstract][Full Text] [Related]
10. The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo.
Knowles JK; Rajadas J; Nguyen TV; Yang T; LeMieux MC; Vander Griend L; Ishikawa C; Massa SM; Wyss-Coray T; Longo FM
J Neurosci; 2009 Aug; 29(34):10627-37. PubMed ID: 19710315
[TBL] [Abstract][Full Text] [Related]
11. Acute administration of the small-molecule p75(NTR) ligand does not prevent hippocampal neuron loss or development of spontaneous seizures after pilocarpine-induced status epilepticus.
Grabenstatter HL; Carlsen J; Raol YH; Yang T; Hund D; Cruz Del Angel Y; White AM; Gonzalez MI; Longo FM; Russek SJ; Brooks-Kayal AR
J Neurosci Res; 2014 Oct; 92(10):1307-18. PubMed ID: 24801281
[TBL] [Abstract][Full Text] [Related]
12. Inactive variants of death receptor p75
Yi C; Goh KY; Wong LW; Ramanujan A; Tanaka K; Sajikumar S; Ibáñez CF
EMBO J; 2021 Jan; 40(2):e104450. PubMed ID: 33258176
[TBL] [Abstract][Full Text] [Related]
13. Neuroimaging, Urinary, and Plasma Biomarkers of Treatment Response in Huntington's Disease: Preclinical Evidence with the p75
Simmons DA; Mills BD; Butler Iii RR; Kuan J; McHugh TLM; Akers C; Zhou J; Syriani W; Grouban M; Zeineh M; Longo FM
Neurotherapeutics; 2021 Apr; 18(2):1039-1063. PubMed ID: 33786806
[TBL] [Abstract][Full Text] [Related]
14. Signaling via the p75 neurotrophin receptor facilitates amyloid-β-induced dendritic spine pathology.
Patnaik A; Zagrebelsky M; Korte M; Holz A
Sci Rep; 2020 Aug; 10(1):13322. PubMed ID: 32770070
[TBL] [Abstract][Full Text] [Related]
15. Selective vulnerability in Alzheimer's disease: amyloid precursor protein and p75(NTR) interaction.
Fombonne J; Rabizadeh S; Banwait S; Mehlen P; Bredesen DE
Ann Neurol; 2009 Mar; 65(3):294-303. PubMed ID: 19334058
[TBL] [Abstract][Full Text] [Related]
16. Knockout of p75 neurotrophin receptor attenuates the hyperphosphorylation of Tau in pR5 mouse model.
Mañucat-Tan NB; Shen LL; Bobrovskaya L; Al-Hawwas M; Zhou FH; Wang YJ; Zhou XF
Aging (Albany NY); 2019 Sep; 11(17):6762-6791. PubMed ID: 31479419
[TBL] [Abstract][Full Text] [Related]
17. Post-Stroke Administration of the p75 Neurotrophin Receptor Modulator, LM11A-31, Attenuates Chronic Changes in Brain Metabolism, Increases Neurotransmitter Levels, and Improves Recovery.
Nguyen TV; Crumpacker RH; Calderon KE; Garcia FG; Zbesko JC; Frye JB; Gonzalez S; Becktel DA; Yang T; Tavera-Garcia MA; Morrison HW; Schnellmann RG; Longo FM; Doyle KP
J Pharmacol Exp Ther; 2022 Feb; 380(2):126-141. PubMed ID: 34893553
[TBL] [Abstract][Full Text] [Related]
18. Modulation of the p75 neurotrophin receptor suppresses age-related basal forebrain cholinergic neuron degeneration.
Xie Y; Meeker RB; Massa SM; Longo FM
Sci Rep; 2019 Mar; 9(1):5273. PubMed ID: 30918278
[TBL] [Abstract][Full Text] [Related]
19. Oral Administration of the p75 Neurotrophin Receptor Modulator, LM11A-31, Improves Erectile Function in a Mouse Model of Cavernous Nerve Injury.
Yin GN; Ock J; Limanjaya A; Minh NN; Hong SS; Yang T; Longo FM; Ryu JK; Suh JK
J Sex Med; 2021 Jan; 18(1):17-28. PubMed ID: 33243690
[TBL] [Abstract][Full Text] [Related]
20. A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice.
Simmons DA; Belichenko NP; Ford EC; Semaan S; Monbureau M; Aiyaswamy S; Holman CM; Condon C; Shamloo M; Massa SM; Longo FM
Hum Mol Genet; 2016 Nov; 25(22):4920-4938. PubMed ID: 28171570
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
