These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. De novo loss-of-function variants in X-linked MED12 are associated with Hardikar syndrome in females. Li D; Strong A; Shen KM; Cassiman D; Van Dyck M; Linhares ND; Valadares ER; Wang T; Pena SDJ; Jaeken J; Vergano S; Zackai E; Hing A; Chow P; Ganguly A; Scholz T; Bierhals T; Philipp D; Hakonarson H; Bhoj E Genet Med; 2021 Apr; 23(4):637-644. PubMed ID: 33244166 [TBL] [Abstract][Full Text] [Related]
4. Missense MED12 variants in 22 males with intellectual disability: From nonspecific symptoms to complete syndromes. Maia N; Ibarluzea N; Misra-Isrie M; Koboldt DC; Marques I; Soares G; Santos R; Marcelis CLM; Keski-Filppula R; Guitart M; Gabau Vila E; Lehman A; Hickey S; Mori M; Terhal P; Valenzuela I; Lasa-Aranzasti A; Cueto-González AM; Chhouk BH; Yeh RC; Neil JE; Abu-Libde B; Kleefstra T; Elting MW; Császár A; Kárteszi J; Bessenyei B; van Bokhoven H; Jorge P; van Hagen JM; de Brouwer APM Am J Med Genet A; 2023 Jan; 191(1):135-143. PubMed ID: 36271811 [TBL] [Abstract][Full Text] [Related]
5. MED12 missense mutation in a three-generation family. Clinical characterization of MED12-related disorders and literature review. Rubinato E; Rondeau S; Giuliano F; Kossorotoff M; Parodi M; Gherbi S; Steffan J; Jonard L; Marlin S Eur J Med Genet; 2020 Mar; 63(3):103768. PubMed ID: 31536828 [TBL] [Abstract][Full Text] [Related]
6. Beyond Ohdo syndrome: A familial missense mutation broadens the MED12 spectrum. Langley KG; Brown J; Gerber RJ; Fox J; Friez MJ; Lyons M; Schrier Vergano SA Am J Med Genet A; 2015 Dec; 167A(12):3180-5. PubMed ID: 26338144 [TBL] [Abstract][Full Text] [Related]
7. Clinical and neurocognitive characterization of a family with a novel MED12 gene frameshift mutation. Lesca G; Moizard MP; Bussy G; Boggio D; Hu H; Haas SA; Ropers HH; Kalscheuer VM; Des Portes V; Labalme A; Sanlaville D; Edery P; Raynaud M; Lespinasse J Am J Med Genet A; 2013 Dec; 161A(12):3063-71. PubMed ID: 24039113 [TBL] [Abstract][Full Text] [Related]
8. Dysregulations of sonic hedgehog signaling in MED12-related X-linked intellectual disability disorders. Srivastava S; Niranjan T; May MM; Tarpey P; Allen W; Hackett A; Jouk PS; Raymond L; Briault S; Skinner C; Toutain A; Gecz J; Heath W; Stevenson RE; Schwartz CE; Wang T Mol Genet Genomic Med; 2019 Apr; 7(4):e00569. PubMed ID: 30729724 [TBL] [Abstract][Full Text] [Related]
9. A novel variant in MED12 gene: Further delineation of phenotype. Narayanan DL; Phadke SR Am J Med Genet A; 2017 Aug; 173(8):2257-2260. PubMed ID: 28544239 [TBL] [Abstract][Full Text] [Related]
10. MED12 Loss-of-Function Variants as a Cause of Congenital Diaphragmatic Hernia in Females With Hardikar Syndrome and Nonspecific Intellectual Disability. Kao EC; Mizerik EA; Bacino CA; Dai H; Vossaert L; Scott DA Am J Med Genet A; 2025 Jan; 197(1):e63868. PubMed ID: 39215511 [TBL] [Abstract][Full Text] [Related]
11. MED12 variants associated with X-linked recessive partial epilepsy without intellectual disability. Yang JH; Liu ZG; Liu CL; Zhang MR; Jia YL; Zhai QX; He MF; He N; Qiao JD Seizure; 2024 Mar; 116():30-36. PubMed ID: 36894399 [TBL] [Abstract][Full Text] [Related]
12. Two male sibs with severe micrognathia and a missense variant in MED12. Prescott TE; Kulseth MA; Heimdal KR; Stadheim B; Hopp E; Gambin T; Coban Akdemir ZH; Jhangiani SN; Muzny DM; Gibbs RA; Lupski JR; Stray-Pedersen A Eur J Med Genet; 2016 Aug; 59(8):367-72. PubMed ID: 27286923 [TBL] [Abstract][Full Text] [Related]
13. Mutations in MED12 cause X-linked Ohdo syndrome. Vulto-van Silfhout AT; de Vries BB; van Bon BW; Hoischen A; Ruiterkamp-Versteeg M; Gilissen C; Gao F; van Zwam M; Harteveld CL; van Essen AJ; Hamel BC; Kleefstra T; Willemsen MA; Yntema HG; van Bokhoven H; Brunner HG; Boyer TG; de Brouwer AP Am J Hum Genet; 2013 Mar; 92(3):401-6. PubMed ID: 23395478 [TBL] [Abstract][Full Text] [Related]
14. MED12 related disorders. Graham JM; Schwartz CE Am J Med Genet A; 2013 Nov; 161A(11):2734-40. PubMed ID: 24123922 [TBL] [Abstract][Full Text] [Related]
15. The power of the Mediator complex-Expanding the genetic architecture and phenotypic spectrum of MED12-related disorders. Charzewska A; Maiwald R; Kahrizi K; Oehl-Jaschkowitz B; Dufke A; Lemke JR; Enders H; Najmabadi H; Tzschach A; Hachmann W; Jensen C; Bienek M; Poznański J; Nawara M; Chilarska T; Obersztyn E; Hoffman-Zacharska D; Gos M; Bal J; Kalscheuer VM Clin Genet; 2018 Nov; 94(5):450-456. PubMed ID: 30006928 [TBL] [Abstract][Full Text] [Related]
16. De novo mutations in genes of mediator complex causing syndromic intellectual disability: mediatorpathy or transcriptomopathy? Caro-Llopis A; Rosello M; Orellana C; Oltra S; Monfort S; Mayo S; Martinez F Pediatr Res; 2016 Dec; 80(6):809-815. PubMed ID: 27500536 [TBL] [Abstract][Full Text] [Related]
17. Qualitative and quantitative analysis of MED12 c.887G>A causing both missense and splicing variants in X-linked Ohdo syndrome. Togi S; Ura H; Niida Y Am J Med Genet A; 2024 Sep; 194(9):e63628. PubMed ID: 38655688 [TBL] [Abstract][Full Text] [Related]
18. MED12 Mutation in Two Families with X-Linked Ohdo Syndrome. Rocchetti L; Evangelista E; De Falco L; Savarese G; Savarese P; Ruggiero R; D'Amore L; Sensi A; Fico A Genes (Basel); 2021 Aug; 12(9):. PubMed ID: 34573309 [TBL] [Abstract][Full Text] [Related]
19. Correspondence on "De novo variants in MED12 cause X-linked syndromic neurodevelopmental disorders in 18 females" by Polla et al. Riccardi F; Astier A; Grisval M; Maillard A; Michaud V; Badens C; Gordon CT; Trimouille A; Faivre L; Amiel J; Sigaudy S; Gorokhova S Genet Med; 2021 Oct; 23(10):2003-2004. PubMed ID: 34079076 [No Abstract] [Full Text] [Related]
20. De Novo Missense Substitutions in the Gene Encoding CDK8, a Regulator of the Mediator Complex, Cause a Syndromic Developmental Disorder. Calpena E; Hervieu A; Kaserer T; Swagemakers SMA; Goos JAC; Popoola O; Ortiz-Ruiz MJ; Barbaro-Dieber T; Bownass L; Brilstra EH; Brimble E; Foulds N; Grebe TA; Harder AVE; Lees MM; Monaghan KG; Newbury-Ecob RA; Ong KR; Osio D; Reynoso Santos FJ; Ruzhnikov MRZ; Telegrafi A; van Binsbergen E; van Dooren MF; ; van der Spek PJ; Blagg J; Twigg SRF; Mathijssen IMJ; Clarke PA; Wilkie AOM Am J Hum Genet; 2019 Apr; 104(4):709-720. PubMed ID: 30905399 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]