BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 33247737)

  • 1. Inhibition of Acetyl-CoA Carboxylase Causes Malformations in Rats and Rabbits: Comparison of Mammalian Findings and Alternative Assays.
    Catlin NR; Bowman CJ; Campion SN; Davenport SD; Esler WP; Kumpf SW; Lewis EM; Nowland WS; Ross TT; Stedman DS; Stethem C; Cappon GD
    Toxicol Sci; 2021 Jan; 179(2):183-194. PubMed ID: 33247737
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acetyl-CoA Carboxylase Inhibition Improves Multiple Dimensions of NASH Pathogenesis in Model Systems.
    Ross TT; Crowley C; Kelly KL; Rinaldi A; Beebe DA; Lech MP; Martinez RV; Carvajal-Gonzalez S; Boucher M; Hirenallur-Shanthappa D; Morin J; Opsahl AC; Vargas SR; Bence KK; Pfefferkorn JA; Esler WP
    Cell Mol Gastroenterol Hepatol; 2020; 10(4):829-851. PubMed ID: 32526482
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice.
    Harada N; Oda Z; Hara Y; Fujinami K; Okawa M; Ohbuchi K; Yonemoto M; Ikeda Y; Ohwaki K; Aragane K; Tamai Y; Kusunoki J
    Mol Cell Biol; 2007 Mar; 27(5):1881-8. PubMed ID: 17210641
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and De Novo Lipogenesis of EGFRvIII Human Glioblastoma Cells.
    Jones JE; Esler WP; Patel R; Lanba A; Vera NB; Pfefferkorn JA; Vernochet C
    PLoS One; 2017; 12(1):e0169566. PubMed ID: 28081256
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acetyl-coenzyme A carboxylase inhibition reduces de novo lipogenesis in overweight male subjects: A randomized, double-blind, crossover study.
    Stiede K; Miao W; Blanchette HS; Beysen C; Harriman G; Harwood HJ; Kelley H; Kapeller R; Schmalbach T; Westlin WF
    Hepatology; 2017 Aug; 66(2):324-334. PubMed ID: 28470676
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.
    Lally JSV; Ghoshal S; DePeralta DK; Moaven O; Wei L; Masia R; Erstad DJ; Fujiwara N; Leong V; Houde VP; Anagnostopoulos AE; Wang A; Broadfield LA; Ford RJ; Foster RA; Bates J; Sun H; Wang T; Liu H; Ray AS; Saha AK; Greenwood J; Bhat S; Harriman G; Miao W; Rocnik JL; Westlin WF; Muti P; Tsakiridis T; Harwood HJ; Kapeller R; Hoshida Y; Tanabe KK; Steinberg GR; Fuchs BC
    Cell Metab; 2019 Jan; 29(1):174-182.e5. PubMed ID: 30244972
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase.
    Lin Y; Yang M; Huang L; Yang F; Fan J; Qiang Y; Chang Y; Zhou W; Yan L; Xiong J; Ping J; Chen S; Men D; Li F
    Cell Rep; 2023 Nov; 42(11):113453. PubMed ID: 37976162
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Acetyl-CoA carboxylase 1-dependent lipogenesis promotes autophagy downstream of AMPK.
    Gross AS; Zimmermann A; Pendl T; Schroeder S; Schoenlechner H; Knittelfelder O; Lamplmayr L; Santiso A; Aufschnaiter A; Waltenstorfer D; Ortonobes Lara S; Stryeck S; Kast C; Ruckenstuhl C; Hofer SJ; Michelitsch B; Woelflingseder M; Müller R; Carmona-Gutierrez D; Madl T; Büttner S; Fröhlich KU; Shevchenko A; Eisenberg T
    J Biol Chem; 2019 Aug; 294(32):12020-12039. PubMed ID: 31209110
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation.
    Jump DB; Torres-Gonzalez M; Olson LK
    Biochem Pharmacol; 2011 Mar; 81(5):649-60. PubMed ID: 21184748
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition.
    Esler WP; Tesz GJ; Hellerstein MK; Beysen C; Sivamani R; Turner SM; Watkins SM; Amor PA; Carvajal-Gonzalez S; Geoly FJ; Biddle KE; Purkal JJ; Fitch M; Buckeridge C; Silvia AM; Griffith DA; Gorgoglione M; Hassoun L; Bosanac SS; Vera NB; Rolph TP; Pfefferkorn JA; Sonnenberg GE
    Sci Transl Med; 2019 May; 11(492):. PubMed ID: 31092695
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription.
    Zhao LF; Iwasaki Y; Zhe W; Nishiyama M; Taguchi T; Tsugita M; Kambayashi M; Hashimoto K; Terada Y
    Endocr J; 2010; 57(4):317-24. PubMed ID: 20139635
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting.
    Huard K; Smith AC; Cappon G; Dow RL; Edmonds DJ; El-Kattan A; Esler WP; Fernando DP; Griffith DA; Kalgutkar AS; Ross TT; Bagley SW; Beebe D; Bi YA; Cabral S; Crowley C; Doran SD; Dowling MS; Liras S; Mascitti V; Niosi M; Pfefferkorn JA; Polivkova J; Préville C; Price DA; Shavnya A; Shirai N; Smith AH; Southers JR; Tess DA; Thuma BA; Varma MV; Yang X
    J Med Chem; 2020 Oct; 63(19):10879-10896. PubMed ID: 32809824
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected].
    Castle JC; Hara Y; Raymond CK; Garrett-Engele P; Ohwaki K; Kan Z; Kusunoki J; Johnson JM
    PLoS One; 2009; 4(2):e4369. PubMed ID: 19190759
    [TBL] [Abstract][Full Text] [Related]  

  • 14. De novo lipogenesis is essential for platelet production in humans.
    Kelly KL; Reagan WJ; Sonnenberg GE; Clasquin M; Hales K; Asano S; Amor PA; Carvajal-Gonzalez S; Shirai N; Matthews MD; Li KW; Hellerstein MK; Vera NB; Ross TT; Cappon G; Bergman A; Buckeridge C; Sun Z; Qejvanaj EZ; Schmahai T; Beebe D; Pfefferkorn JA; Esler WP
    Nat Metab; 2020 Oct; 2(10):1163-1178. PubMed ID: 32929234
    [TBL] [Abstract][Full Text] [Related]  

  • 15.
    Stüve P; Minarrieta L; Erdmann H; Arnold-Schrauf C; Swallow M; Guderian M; Krull F; Hölscher A; Ghorbani P; Behrends J; Abraham WR; Hölscher C; Sparwasser TD; Berod L
    Front Immunol; 2018; 9():495. PubMed ID: 29675017
    [No Abstract]   [Full Text] [Related]  

  • 16. Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals.
    Harwood HJ; Petras SF; Shelly LD; Zaccaro LM; Perry DA; Makowski MR; Hargrove DM; Martin KA; Tracey WR; Chapman JG; Magee WP; Dalvie DK; Soliman VF; Martin WH; Mularski CJ; Eisenbeis SA
    J Biol Chem; 2003 Sep; 278(39):37099-111. PubMed ID: 12842871
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.
    Guilherme A; Rowland LA; Wetoska N; Tsagkaraki E; Santos KB; Bedard AH; Henriques F; Kelly M; Munroe S; Pedersen DJ; Ilkayeva OR; Koves TR; Tauer L; Pan M; Han X; Kim JK; Newgard CB; Muoio DM; Czech MP
    Cell Rep; 2023 May; 42(5):112488. PubMed ID: 37163372
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acetyl-CoA carboxylases 1 and 2 show distinct expression patterns in rats and humans and alterations in obesity and diabetes.
    Kreuz S; Schoelch C; Thomas L; Rist W; Rippmann JF; Neubauer H
    Diabetes Metab Res Rev; 2009 Sep; 25(6):577-86. PubMed ID: 19618481
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Acetyl-CoA carboxylase from yeast is an essential enzyme and is regulated by factors that control phospholipid metabolism.
    Hasslacher M; Ivessa AS; Paltauf F; Kohlwein SD
    J Biol Chem; 1993 May; 268(15):10946-52. PubMed ID: 8098706
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal.
    Abu-Elheiga L; Matzuk MM; Kordari P; Oh W; Shaikenov T; Gu Z; Wakil SJ
    Proc Natl Acad Sci U S A; 2005 Aug; 102(34):12011-6. PubMed ID: 16103361
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.