258 related articles for article (PubMed ID: 33248713)
21. New quinoline/chalcone hybrids as anti-cancer agents: Design, synthesis, and evaluations of cytotoxicity and PI3K inhibitory activity.
Abbas SH; Abd El-Hafeez AA; Shoman ME; Montano MM; Hassan HA
Bioorg Chem; 2019 Feb; 82():360-377. PubMed ID: 30428415
[TBL] [Abstract][Full Text] [Related]
22. Design, synthesis and anticancer evaluation of acridine hydroxamic acid derivatives as dual Topo and HDAC inhibitors.
Chen J; Li D; Li W; Yin J; Zhang Y; Yuan Z; Gao C; Liu F; Jiang Y
Bioorg Med Chem; 2018 Aug; 26(14):3958-3966. PubMed ID: 29954683
[TBL] [Abstract][Full Text] [Related]
23. Synthesis and biological evaluation of diaryl urea derivatives designed as potential anticarcinoma agents using de novo structure-based lead optimization approach.
Azimian F; Hamzeh-Mivehroud M; Shahbazi Mojarrad J; Hemmati S; Dastmalchi S
Eur J Med Chem; 2020 Sep; 201():112461. PubMed ID: 32663641
[TBL] [Abstract][Full Text] [Related]
24. Identification of topoisomerases as molecular targets of cytosporolide C and its analog.
Otake K; Yamada K; Miura K; Sasazawa Y; Miyazaki S; Niwa Y; Ogura A; Takao KI; Simizu S
Bioorg Med Chem; 2019 Aug; 27(15):3334-3338. PubMed ID: 31204230
[TBL] [Abstract][Full Text] [Related]
25. Identification of new halogen-containing 2,4-diphenyl indenopyridin-5-one derivative as a boosting agent for the anticancer responses of clinically available topoisomerase inhibitors.
Hwang SY; Shrestha A; Park S; Bist G; Kunwar S; Kadayat TM; Jang H; Seo M; Sheen N; Kim S; Jeon KH; Lee ES; Kwon Y
Eur J Med Chem; 2022 Jan; 227():113916. PubMed ID: 34678573
[TBL] [Abstract][Full Text] [Related]
26. The synthesis and anticancer activities of chiral epoxy-substituted chromone analogs.
Jo H; Hee Seo S; Na Y; Kwon Y
Bioorg Chem; 2019 Mar; 84():347-354. PubMed ID: 30530076
[TBL] [Abstract][Full Text] [Related]
27. Discovery of novel rigid analogs of 2-naphthol with potent anticancer activity through multi-target topoisomerase I & II and tyrosine kinase receptor EGFR & VEGFR-2 inhibition mechanism.
El-Mawgoud HKA; Fouda AM; El-Nassag MAA; Elhenawy AA; Alshahrani MY; El-Agrody AM
Chem Biol Interact; 2022 Mar; 355():109838. PubMed ID: 35123995
[TBL] [Abstract][Full Text] [Related]
28. Discovery of novel triazolophthalazine derivatives as DNA intercalators and topoisomerase II inhibitors.
Sakr H; Ayyad RR; El-Helby AA; Khalifa MM; Mahdy HA
Arch Pharm (Weinheim); 2021 Jun; 354(6):e2000456. PubMed ID: 33554352
[TBL] [Abstract][Full Text] [Related]
29. Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity.
Nemr MTM; Sonousi A; Marzouk AA
Bioorg Chem; 2020 Dec; 105():104446. PubMed ID: 33171405
[TBL] [Abstract][Full Text] [Related]
30. Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis.
Mohamed TK; Batran RZ; Elseginy SA; Ali MM; Mahmoud AE
Bioorg Chem; 2019 Apr; 85():253-273. PubMed ID: 30641320
[TBL] [Abstract][Full Text] [Related]
31. Synthesis of Novel Pyrazole Derivatives as Promising DNA-Binding Agents and Evaluation of Antitumor and Antitopoisomerases I/II Activities.
Feng J; Qi H; Sun X; Feng S; Liu Z; Song Y; Qiao X
Chem Pharm Bull (Tokyo); 2018 Nov; 66(11):1065-1071. PubMed ID: 30197406
[TBL] [Abstract][Full Text] [Related]
32. Novel piperazine-chalcone hybrids and related pyrazoline analogues targeting VEGFR-2 kinase; design, synthesis, molecular docking studies, and anticancer evaluation.
Ahmed MF; Santali EY; El-Haggar R
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):307-318. PubMed ID: 33349069
[TBL] [Abstract][Full Text] [Related]
33. Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy.
Ibrahim TS; Hawwas MM; Taher ES; Alhakamy NA; Alfaleh MA; Elagawany M; Elgendy B; Zayed GM; Mohamed MFA; Abdel-Samii ZK; Elshaier YAMM
Bioorg Chem; 2020 Dec; 105():104352. PubMed ID: 33080494
[TBL] [Abstract][Full Text] [Related]
34. Inhibition of the ATPase Domain of Human Topoisomerase IIa on HepG2 Cells by 1, 2-benzenedicarboxylic Acid, Mono (2-ethylhexyl) Ester: Molecular Docking and Dynamics Simulations.
Selvakumar JN; Chandrasekaran SD; Doss GPC; Kumar TD
Curr Cancer Drug Targets; 2019; 19(6):495-503. PubMed ID: 30479215
[TBL] [Abstract][Full Text] [Related]
35. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
[TBL] [Abstract][Full Text] [Related]
36. Synthesis of carbazole derivatives containing chalcone analogs as non-intercalative topoisomerase II catalytic inhibitors and apoptosis inducers.
Li PH; Jiang H; Zhang WJ; Li YL; Zhao MC; Zhou W; Zhang LY; Tang YD; Dong CZ; Huang ZS; Chen HX; Du ZY
Eur J Med Chem; 2018 Feb; 145():498-510. PubMed ID: 29335211
[TBL] [Abstract][Full Text] [Related]
37. New chalcone derivative exhibits antiproliferative potential by inducing G2/M cell cycle arrest, mitochondrial-mediated apoptosis and modulation of MAPK signalling pathway.
Takac P; Kello M; Pilatova MB; Kudlickova Z; Vilkova M; Slepcikova P; Petik P; Mojzis J
Chem Biol Interact; 2018 Aug; 292():37-49. PubMed ID: 29981726
[TBL] [Abstract][Full Text] [Related]
38. Synthesis and biological evaluation of novel xanthine derivatives as potential apoptotic antitumor agents.
Hisham M; Youssif BGM; Osman EEA; Hayallah AM; Abdel-Aziz M
Eur J Med Chem; 2019 Aug; 176():117-128. PubMed ID: 31108261
[TBL] [Abstract][Full Text] [Related]
39. 1,2,3-Triazole-Chalcone hybrids: Synthesis, in vitro cytotoxic activity and mechanistic investigation of apoptosis induction in multiple myeloma RPMI-8226.
Ashour HF; Abou-Zeid LA; El-Sayed MA; Selim KB
Eur J Med Chem; 2020 Mar; 189():112062. PubMed ID: 31986406
[TBL] [Abstract][Full Text] [Related]
40. Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers.
Abbass EM; Khalil AK; Mohamed MM; Eissa IH; El-Naggar AM
Bioorg Chem; 2020 Nov; 104():104255. PubMed ID: 32927130
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]