BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 33249692)

  • 1. Down-regulation of dual-specificity phosphatase 6, a negative regulator of oncogenic ERK signaling, by ACA-28 induces apoptosis in NIH/3T3 cells overexpressing HER2/ErbB2.
    Kanda Y; Mizuno A; Takasaki T; Satoh R; Hagihara K; Masuko T; Endo Y; Tanabe G; Sugiura R
    Genes Cells; 2021 Feb; 26(2):109-116. PubMed ID: 33249692
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Fission Yeast as a Model System for Studying Cancer Signaling and Drug Discovery: Discovery of ACA-28 as a Novel Inducer of ERK-dependent Apoptosis Reveals a New Cancer Therapy].
    Sugiura R
    Yakugaku Zasshi; 2019; 139(5):753-758. PubMed ID: 31061345
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of ACA-28, a 1'-acetoxychavicol acetate analogue compound, as a novel modulator of ERK MAPK signaling, which preferentially kills human melanoma cells.
    Satoh R; Hagihara K; Matsuura K; Manse Y; Kita A; Kunoh T; Masuko T; Moriyama M; Moriyama H; Tanabe G; Muraoka O; Sugiura R
    Genes Cells; 2017 Jul; 22(7):608-618. PubMed ID: 28485554
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DUSP5 and DUSP6, two ERK specific phosphatases, are markers of a higher MAPK signaling activation in BRAF mutated thyroid cancers.
    Buffet C; Hecale-Perlemoine K; Bricaire L; Dumont F; Baudry C; Tissier F; Bertherat J; Cochand-Priollet B; Raffin-Sanson ML; Cormier F; Groussin L
    PLoS One; 2017; 12(9):e0184861. PubMed ID: 28910386
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells.
    Zhang Z; Kobayashi S; Borczuk AC; Leidner RS; Laframboise T; Levine AD; Halmos B
    Carcinogenesis; 2010 Apr; 31(4):577-86. PubMed ID: 20097731
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dual-specificity phosphatase 6 deletion protects the colonic epithelium against inflammation and promotes both proliferation and tumorigenesis.
    Beaudry K; Langlois MJ; Montagne A; Cagnol S; Carrier JC; Rivard N
    J Cell Physiol; 2019 May; 234(5):6731-6745. PubMed ID: 30273442
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dusp6 inhibits epithelial-mesenchymal transition in endometrial adenocarcinoma via ERK signaling pathway.
    Fan MJ; Liang SM; He PJ; Zhao XB; Li MJ; Geng F
    Radiol Oncol; 2019 Sep; 53(3):307-315. PubMed ID: 31553703
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Follicle-Stimulating Hormone (FSH)-dependent Regulation of Extracellular Regulated Kinase (ERK) Phosphorylation by the Mitogen-activated Protein (MAP) Kinase Phosphatase MKP3.
    Donaubauer EM; Law NC; Hunzicker-Dunn ME
    J Biol Chem; 2016 Sep; 291(37):19701-12. PubMed ID: 27422819
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A parental requirement for dual-specificity phosphatase 6 in zebrafish.
    Maurer JM; Sagerström CG
    BMC Dev Biol; 2018 Mar; 18(1):6. PubMed ID: 29544468
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nuclear-Biased DUSP6 Expression is Associated with Cancer Spreading Including Brain Metastasis in Triple-Negative Breast Cancer.
    Wu F; McCuaig RD; Sutton CR; Tan AHY; Jeelall Y; Bean EG; Dai J; Prasanna T; Batham J; Malik L; Yip D; Dahlstrom JE; Rao S
    Int J Mol Sci; 2019 Jun; 20(12):. PubMed ID: 31238530
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dusp6 attenuates Ras/MAPK signaling to limit zebrafish heart regeneration.
    Missinato MA; Saydmohammed M; Zuppo DA; Rao KS; Opie GW; Kühn B; Tsang M
    Development; 2018 Mar; 145(5):. PubMed ID: 29444893
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neuroprotective effect of dual specificity phosphatase 6 against glutamate-induced cytotoxicity in mouse hippocampal neurons.
    Huang X; Liao W; Huang Y; Jiang M; Chen J; Wang M; Lin H; Guan S; Liu J
    Biomed Pharmacother; 2017 Jul; 91():385-392. PubMed ID: 28475917
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tripartite motif protein 11 (TRIM11), an oncogene for human lung cancer via the DUSP6-mediated ERK1/2 signaling pathway.
    Wang XL; Lu SC; Sun C; Jin WG; Fan YW; Shu YS; Shi HC; Min LF
    Cancer Biol Ther; 2021 Apr; 22(4):324-332. PubMed ID: 33970779
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Post-transcriptional regulation of the DUSP6/MKP-3 phosphatase by MEK/ERK signaling and hypoxia.
    Bermudez O; Jouandin P; Rottier J; Bourcier C; Pagès G; Gimond C
    J Cell Physiol; 2011 Jan; 226(1):276-84. PubMed ID: 20665674
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter.
    Ekerot M; Stavridis MP; Delavaine L; Mitchell MP; Staples C; Owens DM; Keenan ID; Dickinson RJ; Storey KG; Keyse SM
    Biochem J; 2008 Jun; 412(2):287-98. PubMed ID: 18321244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dual-specificity phosphatase 6 plays a critical role in the maintenance of a cancer stem-like cell phenotype in human endometrial cancer.
    Kato M; Onoyama I; Yoshida S; Cui L; Kawamura K; Kodama K; Hori E; Matsumura Y; Yagi H; Asanoma K; Yahata H; Itakura A; Takeda S; Kato K
    Int J Cancer; 2020 Oct; 147(7):1987-1999. PubMed ID: 32159851
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity.
    Ingram K; Samson SC; Zewdu R; Zitnay RG; Snyder EL; Mendoza MC
    Oncogene; 2022 Jan; 41(2):293-300. PubMed ID: 34689179
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells.
    Unni AM; Harbourne B; Oh MH; Wild S; Ferrarone JR; Lockwood WW; Varmus H
    Elife; 2018 Nov; 7():. PubMed ID: 30475204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DUSP6 is a novel transcriptional target of p53 and regulates p53-mediated apoptosis by modulating expression levels of Bcl-2 family proteins.
    Piya S; Kim JY; Bae J; Seol DW; Moon AR; Kim TH
    FEBS Lett; 2012 Nov; 586(23):4233-40. PubMed ID: 23108049
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Down-regulation of DUSP6 expression in lung cancer: its mechanism and potential role in carcinogenesis.
    Okudela K; Yazawa T; Woo T; Sakaeda M; Ishii J; Mitsui H; Shimoyamada H; Sato H; Tajiri M; Ogawa N; Masuda M; Takahashi T; Sugimura H; Kitamura H
    Am J Pathol; 2009 Aug; 175(2):867-81. PubMed ID: 19608870
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.