BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 33267758)

  • 1. CYP2C and CYP2B Mediated Metabolic Activation of Retrorsine in Cyp3a Knockout Mice.
    Pang X; Tang C; Kong F; Chen M; Chen X
    Curr Drug Metab; 2020; 21(13):1040-1051. PubMed ID: 33267758
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolic Activation of Retrorsine may Disrupt Bile Acid Homeostasis in Mice through the Nrf2 Pathway.
    Pang X; Tang C; Cao P; Zhou L; Chen X
    Curr Drug Metab; 2021; 22(11):870-881. PubMed ID: 33906588
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Activity and induction of CYP2B, CYP2C, and CYP3A in tissues of cyclophosphane-sensitive and resistant neoplasms and the liver of neoplasm-carrying mice].
    Grishanov AIu; Kaledin VI; Zueva TV; Nekhoroshkova EK; Nikolin VP; Liakhovich VV
    Biomed Khim; 2003; 49(1):27-34. PubMed ID: 14569871
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The roles of CYP3A and CYP2B isoforms in hepatic bioactivation and detoxification of the pyrrolizidine alkaloid senecionine in sheep and hamsters.
    Huan JY; Miranda CL; Buhler DR; Cheeke PR
    Toxicol Appl Pharmacol; 1998 Aug; 151(2):229-35. PubMed ID: 9707499
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice.
    Kumar R; Mota LC; Litoff EJ; Rooney JP; Boswell WT; Courter E; Henderson CM; Hernandez JP; Corton JC; Moore DD; Baldwin WS
    PLoS One; 2017; 12(3):e0174355. PubMed ID: 28350814
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.
    Wang YP; Yan J; Fu PP; Chou MW
    Toxicol Lett; 2005 Mar; 155(3):411-20. PubMed ID: 15649625
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolic activation of the tumorigenic pyrrolizidine alkaloid, retrorsine, leading to DNA adduct formation in vivo.
    Wang YP; Fu PP; Chou MW
    Int J Environ Res Public Health; 2005 Apr; 2(1):74-9. PubMed ID: 16705803
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Effect of shenfu injection on CYP450s of rat liver].
    Li H; Wang YG; Ma ZC; Zhou SS; Liang QD; Xiao CR; Tan HL; Tang XL; Li H; Shen GL; Zhang BL; Gao Y
    Yao Xue Xue Bao; 2013 May; 48(5):728-33. PubMed ID: 23888697
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparison of hepatic in vitro metabolism of the pyrrolizidine alkaloid senecionine in sheep and cattle.
    Duringer JM; Buhler DR; Craig AM
    Am J Vet Res; 2004 Nov; 65(11):1563-72. PubMed ID: 15566096
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The effect of spironolactone treatment on the cytochrome P450-mediated metabolism of the pyrrolizidine alkaloid senecionine by hepatic microsomes from rats and guinea pigs.
    Chung WG; Buhler DR
    Toxicol Appl Pharmacol; 1994 Aug; 127(2):314-9. PubMed ID: 8048076
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of hepatic cyp2b and cyp3a subfamily enzymes by nicardipine and nifedipine in mice.
    Konno Y; Sekimoto M; Nemoto K; Degawa M
    Xenobiotica; 2004 Jul; 34(7):607-18. PubMed ID: 15672751
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolic Disposition of Triazolam and Clobazam in Humanized CYP3A Mice with a Double-Knockout Background of Mouse
    Kobayashi K; Minegishi G; Kuriyama N; Miyajima A; Abe S; Kazuki K; Kazuki Y
    Drug Metab Dispos; 2023 Feb; 51(2):174-182. PubMed ID: 36379710
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: correlation study with induction in vivo.
    Cui X; Thomas A; Han Y; Palamanda J; Montgomery D; White RE; Morrison RA; Cheng KC
    J Pharmacol Toxicol Methods; 2005; 52(2):234-43. PubMed ID: 16125621
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of the impact of 16-dehydropregnenolone on the activity and expression of rat hepatic cytochrome P450 enzymes.
    Ramakrishna R; Bhateria M; Singh R; Bhatta RS
    J Steroid Biochem Mol Biol; 2016 Oct; 163():183-92. PubMed ID: 27224941
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein Kinase N Family Negatively Regulates Constitutive Androstane Receptor-Mediated Transcriptional Induction of Cytochrome P450 2b10 in the Livers of Mice.
    Kawase A; Mukai H; Tateishi S; Kuroda S; Kazaoka A; Satoh R; Shimada H; Sugiura R; Iwaki M
    J Pharmacol Exp Ther; 2021 Oct; 379(1):53-63. PubMed ID: 34312179
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rat and human liver cytochrome P-450 isoform metabolism of ecteinascidin 743 does not predict gender-dependent toxicity in humans.
    Reid JM; Kuffel MJ; Ruben SL; Morales JJ; Rinehart KL; Squillace DP; Ames MM
    Clin Cancer Res; 2002 Sep; 8(9):2952-62. PubMed ID: 12231541
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolic activation of retronecine and retronecine N-oxide - formation of DHP-derived DNA adducts.
    Yan J; Xia Q; Chou MW; Fu PP
    Toxicol Ind Health; 2008 Apr; 24(3):181-8. PubMed ID: 18842697
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of cytochrome P450IIIA4 in the metabolism of the pyrrolizidine alkaloid senecionine in human liver.
    Miranda CL; Reed RL; Guengerich FP; Buhler DR
    Carcinogenesis; 1991 Mar; 12(3):515-9. PubMed ID: 2009596
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.
    Park YJ; Lee EK; Lee YK; Park DJ; Jang HC; Moore DD
    Toxicol Appl Pharmacol; 2012 Sep; 263(2):131-7. PubMed ID: 22503787
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of Chronic Renal Failure on Brain Cytochrome P450 in Rats.
    Naud J; Harding J; Lamarche C; Beauchemin S; Leblond FA; Pichette V
    Drug Metab Dispos; 2016 Aug; 44(8):1174-9. PubMed ID: 27271372
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.