878 related articles for article (PubMed ID: 33269665)
1. Human CTC1 promotes TopBP1 stability and CHK1 phosphorylation in response to telomere dysfunction and global replication stress.
Ackerson SM; Gable CI; Stewart JA
Cell Cycle; 2020 Dec; 19(24):3491-3507. PubMed ID: 33269665
[TBL] [Abstract][Full Text] [Related]
2. Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling.
Choi JH; Lindsey-Boltz LA; Kemp M; Mason AC; Wold MS; Sancar A
Proc Natl Acad Sci U S A; 2010 Aug; 107(31):13660-5. PubMed ID: 20616048
[TBL] [Abstract][Full Text] [Related]
3. CST in maintaining genome stability: Beyond telomeres.
Lyu X; Sang PB; Chai W
DNA Repair (Amst); 2021 Jun; 102():103104. PubMed ID: 33780718
[TBL] [Abstract][Full Text] [Related]
4. Protection of telomeres 1 proteins POT1a and POT1b can repress ATR signaling by RPA exclusion, but binding to CST limits ATR repression by POT1b.
Kratz K; de Lange T
J Biol Chem; 2018 Sep; 293(37):14384-14392. PubMed ID: 30082315
[TBL] [Abstract][Full Text] [Related]
5. Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer.
Liu K; Graves JD; Lin FT; Lin WC
J Biol Chem; 2021; 296():100382. PubMed ID: 33556369
[TBL] [Abstract][Full Text] [Related]
6. TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA.
Flynn RL; Centore RC; O'Sullivan RJ; Rai R; Tse A; Songyang Z; Chang S; Karlseder J; Zou L
Nature; 2011 Mar; 471(7339):532-6. PubMed ID: 21399625
[TBL] [Abstract][Full Text] [Related]
7. RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR.
Lyu K; Kumagai A; Dunphy WG
Cell Cycle; 2019 Apr; 18(8):898-913. PubMed ID: 30975033
[TBL] [Abstract][Full Text] [Related]
8. RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling.
Lindsey-Boltz LA; Kemp MG; Capp C; Sancar A
Cell Cycle; 2015; 14(1):99-108. PubMed ID: 25602520
[TBL] [Abstract][Full Text] [Related]
9. Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1).
Lindsey-Boltz LA; Sancar A
J Biol Chem; 2011 Jun; 286(22):19229-36. PubMed ID: 21502314
[TBL] [Abstract][Full Text] [Related]
10. ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation.
Ball HL; Myers JS; Cortez D
Mol Biol Cell; 2005 May; 16(5):2372-81. PubMed ID: 15743907
[TBL] [Abstract][Full Text] [Related]
11. ATR autophosphorylation as a molecular switch for checkpoint activation.
Liu S; Shiotani B; Lahiri M; Maréchal A; Tse A; Leung CC; Glover JN; Yang XH; Zou L
Mol Cell; 2011 Jul; 43(2):192-202. PubMed ID: 21777809
[TBL] [Abstract][Full Text] [Related]
12. Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.
Liu S; Opiyo SO; Manthey K; Glanzer JG; Ashley AK; Amerin C; Troksa K; Shrivastav M; Nickoloff JA; Oakley GG
Nucleic Acids Res; 2012 Nov; 40(21):10780-94. PubMed ID: 22977173
[TBL] [Abstract][Full Text] [Related]
13. ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA.
Zhang H; Head PE; Daddacha W; Park SH; Li X; Pan Y; Madden MZ; Duong DM; Xie M; Yu B; Warren MD; Liu EA; Dhere VR; Li C; Pradilla I; Torres MA; Wang Y; Dynan WS; Doetsch PW; Deng X; Seyfried NT; Gius D; Yu DS
Cell Rep; 2016 Feb; 14(6):1435-1447. PubMed ID: 26854234
[TBL] [Abstract][Full Text] [Related]
14. Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1.
Shiotani B; Nguyen HD; Håkansson P; Maréchal A; Tse A; Tahara H; Zou L
Cell Rep; 2013 May; 3(5):1651-62. PubMed ID: 23684611
[TBL] [Abstract][Full Text] [Related]
15. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.
Zou L; Elledge SJ
Science; 2003 Jun; 300(5625):1542-8. PubMed ID: 12791985
[TBL] [Abstract][Full Text] [Related]
16. Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1.
Sivasubramaniam S; Sun X; Pan YR; Wang S; Lee EY
Genes Dev; 2008 Mar; 22(5):587-600. PubMed ID: 18283122
[TBL] [Abstract][Full Text] [Related]
17. RBMX is required for activation of ATR on repetitive DNAs to maintain genome stability.
Zheng T; Zhou H; Li X; Peng D; Yang Y; Zeng Y; Liu H; Ren J; Zhao Y
Cell Death Differ; 2020 Nov; 27(11):3162-3176. PubMed ID: 32494026
[TBL] [Abstract][Full Text] [Related]
18. DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe.
Ashley AK; Shrivastav M; Nie J; Amerin C; Troksa K; Glanzer JG; Liu S; Opiyo SO; Dimitrova DD; Le P; Sishc B; Bailey SM; Oakley GG; Nickoloff JA
DNA Repair (Amst); 2014 Sep; 21():131-9. PubMed ID: 24819595
[TBL] [Abstract][Full Text] [Related]
19. Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation.
Liu S; Bekker-Jensen S; Mailand N; Lukas C; Bartek J; Lukas J
Mol Cell Biol; 2006 Aug; 26(16):6056-64. PubMed ID: 16880517
[TBL] [Abstract][Full Text] [Related]
20. S-phase sensing of DNA-protein crosslinks triggers TopBP1-independent ATR activation and p53-mediated cell death by formaldehyde.
Wong VC; Cash HL; Morse JL; Lu S; Zhitkovich A
Cell Cycle; 2012 Jul; 11(13):2526-37. PubMed ID: 22722496
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]