132 related articles for article (PubMed ID: 33277385)
1. Adenovirus Vector-Induced IL-6 Promotes Leaky Adenoviral Gene Expression, Leading to Acute Hepatotoxicity.
Shimizu K; Sakurai F; Iizuka S; Ono R; Tsukamoto T; Nishimae F; Nakamura SI; Nishinaka T; Terada T; Fujio Y; Mizuguchi H
J Immunol; 2021 Jan; 206(2):410-421. PubMed ID: 33277385
[TBL] [Abstract][Full Text] [Related]
2. Transduction Properties of an Adenovirus Vector Containing Sequences Complementary to a Liver-Specific microRNA, miR-122a, in the 3'-Untranslated Region of the E4 Gene in Human Hepatocytes from Chimeric Mice with Humanized Liver.
Sakurai F; Tsukamoto T; Ono R; Nishimae F; Shiota A; Iizuka S; Shimizu K; Sakai E; Ishida Y; Tateno C; Chayama K; Mizuguchi H
Biol Pharm Bull; 2021; 44(10):1506-1513. PubMed ID: 34602559
[TBL] [Abstract][Full Text] [Related]
3. [Development and Characterization of a Novel Adenovirus Vector Exhibiting MicroRNA-mediated Suppression of the Leaky Expression of Adenovirus Genes].
Shimizu K
Yakugaku Zasshi; 2015; 135(12):1349-56. PubMed ID: 26632150
[TBL] [Abstract][Full Text] [Related]
4. Neonatal Gene Therapy for Hemophilia B by a Novel Adenovirus Vector Showing Reduced Leaky Expression of Viral Genes.
Iizuka S; Sakurai F; Tachibana M; Ohashi K; Mizuguchi H
Mol Ther Methods Clin Dev; 2017 Sep; 6():183-193. PubMed ID: 28828393
[TBL] [Abstract][Full Text] [Related]
5. Suppression of leaky expression of adenovirus genes by insertion of microRNA-targeted sequences in the replication-incompetent adenovirus vector genome.
Shimizu K; Sakurai F; Tomita K; Nagamoto Y; Nakamura S; Katayama K; Tachibana M; Kawabata K; Mizuguchi H
Mol Ther Methods Clin Dev; 2014; 1():14035. PubMed ID: 26015975
[TBL] [Abstract][Full Text] [Related]
6. NF-κB promotes leaky expression of adenovirus genes in a replication-incompetent adenovirus vector.
Machitani M; Sakurai F; Wakabayashi K; Nakatani K; Shimizu K; Tachibana M; Mizuguchi H
Sci Rep; 2016 Jan; 6():19922. PubMed ID: 26814140
[TBL] [Abstract][Full Text] [Related]
7. [Development of a novel adenovirus vector exhibiting microRNA-mediated suppression of the leaky expression of adenovirus genes].
Shimizu K; Sakurai F; Tachibana M; Mizuguchi H
Yakugaku Zasshi; 2012; 132(12):1407-12. PubMed ID: 23208048
[TBL] [Abstract][Full Text] [Related]
8. Quantitative analysis of the leaky expression of adenovirus genes in cells transduced with a replication-incompetent adenovirus vector.
Shimizu K; Sakurai F; Machitani M; Katayama K; Mizuguchi H
Mol Pharm; 2011 Aug; 8(4):1430-5. PubMed ID: 21682288
[TBL] [Abstract][Full Text] [Related]
9. Fiber-modified adenovirus vectors decrease liver toxicity through reduced IL-6 production.
Koizumi N; Yamaguchi T; Kawabata K; Sakurai F; Sasaki T; Watanabe Y; Hayakawa T; Mizuguchi H
J Immunol; 2007 Feb; 178(3):1767-73. PubMed ID: 17237426
[TBL] [Abstract][Full Text] [Related]
10. Efficient attenuation of NK cell-mediated liver injury through genetically manipulating multiple immunogenes by using a liver-directed vector.
Geng J; Wang X; Wei H; Sun R; Tian Z
J Immunol; 2013 May; 190(9):4821-9. PubMed ID: 23554312
[TBL] [Abstract][Full Text] [Related]
11. Respective roles of TNF-alpha and IL-6 in the immune response-elicited by adenovirus-mediated gene transfer in mice.
Benihoud K; Esselin S; Descamps D; Jullienne B; Salone B; Bobé P; Bonardelle D; Connault E; Opolon P; Saggio I; Perricaudet M
Gene Ther; 2007 Mar; 14(6):533-44. PubMed ID: 17109009
[TBL] [Abstract][Full Text] [Related]
12. miR-122a-regulated expression of a suicide gene prevents hepatotoxicity without altering antitumor effects in suicide gene therapy.
Suzuki T; Sakurai F; Nakamura S; Kouyama E; Kawabata K; Kondoh M; Yagi K; Mizuguchi H
Mol Ther; 2008 Oct; 16(10):1719-26. PubMed ID: 18665157
[TBL] [Abstract][Full Text] [Related]
13. Reduced toxicity, attenuated immunogenicity and efficient mediation of human p53 gene expression in vivo by an adenovirus vector with deleted E1-E3 and inactivated E4 by GAL4-TATA promoter replacement.
Ji L; Bouvet M; Price RE; Roth JA; Fang B
Gene Ther; 1999 Mar; 6(3):393-402. PubMed ID: 10435089
[TBL] [Abstract][Full Text] [Related]
14. Development of an Improved Adenovirus Vector and Its Application to the Treatment of Lifestyle-Related Diseases.
Shimizu K
Biol Pharm Bull; 2024; 47(5):886-894. PubMed ID: 38692864
[TBL] [Abstract][Full Text] [Related]
15. Adenoviral expression of suppressor of cytokine signaling-1 reduces adenovirus vector-induced innate immune responses.
Sakurai H; Tashiro K; Kawabata K; Yamaguchi T; Sakurai F; Nakagawa S; Mizuguchi H
J Immunol; 2008 Apr; 180(7):4931-8. PubMed ID: 18354218
[TBL] [Abstract][Full Text] [Related]
16. Suppressive effects of sugar-modified cationic liposome/NF-kappaB decoy complexes on adenovirus vector-induced innate immune responses.
Huang H; Sakurai F; Higuchi Y; Kawakami S; Hashida M; Kawabata K; Mizuguchi H
J Control Release; 2009 Jan; 133(2):139-45. PubMed ID: 18977256
[TBL] [Abstract][Full Text] [Related]
17. Further reduction in adenovirus vector-mediated liver transduction without largely affecting transgene expression in target organ by exploiting microrna-mediated regulation and the Cre-loxP recombination system.
Bennett D; Sakurai F; Shimizu K; Matsui H; Tomita K; Suzuki T; Katayama K; Kawabata K; Mizuguchi H
Mol Pharm; 2012 Dec; 9(12):3452-63. PubMed ID: 23127182
[TBL] [Abstract][Full Text] [Related]
18. Induction of immunological tolerance to adenoviral vectors by using a novel dendritic cell-based strategy.
Kushwah R; Oliver JR; Duan R; Zhang L; Keshavjee S; Hu J
J Virol; 2012 Apr; 86(7):3422-35. PubMed ID: 22258241
[TBL] [Abstract][Full Text] [Related]
19. Expression of human interleukin-1 receptor antagonist in mouse lungs using a recombinant adenovirus: effects on vector-induced inflammation.
McCoy RD; Davidson BL; Roessler BJ; Huffnagle GB; Simon RH
Gene Ther; 1995 Sep; 2(7):437-42. PubMed ID: 7584121
[TBL] [Abstract][Full Text] [Related]
20. Adenovirus serotype 35 vector-induced innate immune responses in dendritic cells derived from wild-type and human CD46-transgenic mice: Comparison with a fiber-substituted Ad vector containing fiber proteins of Ad serotype 35.
Sakurai F; Nakashima K; Yamaguchi T; Ichinose T; Kawabata K; Hayakawa T; Mizuguchi H
J Control Release; 2010 Dec; 148(2):212-8. PubMed ID: 20800630
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]