BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

540 related articles for article (PubMed ID: 33278637)

  • 1. LKB1 deficiency-induced metabolic reprogramming in tumorigenesis and non-neoplastic diseases.
    Zhang Y; Meng Q; Sun Q; Xu ZX; Zhou H; Wang Y
    Mol Metab; 2021 Feb; 44():101131. PubMed ID: 33278637
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α.
    Faubert B; Vincent EE; Griss T; Samborska B; Izreig S; Svensson RU; Mamer OA; Avizonis D; Shackelford DB; Shaw RJ; Jones RG
    Proc Natl Acad Sci U S A; 2014 Feb; 111(7):2554-9. PubMed ID: 24550282
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Posttranslational regulation of liver kinase B1 in human cancer.
    Hu L; Liu M; Tang B; Li Q; Pan BS; Xu C; Lin HK
    J Biol Chem; 2023 Apr; 299(4):104570. PubMed ID: 36870679
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism.
    Jansen M; Ten Klooster JP; Offerhaus GJ; Clevers H
    Physiol Rev; 2009 Jul; 89(3):777-98. PubMed ID: 19584313
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity.
    Forcet C; Etienne-Manneville S; Gaude H; Fournier L; Debilly S; Salmi M; Baas A; Olschwang S; Clevers H; Billaud M
    Hum Mol Genet; 2005 May; 14(10):1283-92. PubMed ID: 15800014
    [TBL] [Abstract][Full Text] [Related]  

  • 6. LKB1 and cancer: The dual role of metabolic regulation.
    Li TT; Zhu HB
    Biomed Pharmacother; 2020 Dec; 132():110872. PubMed ID: 33068936
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of β-Catenin Activity Abolishes LKB1 Loss-Driven Pancreatic Cystadenoma in Mice.
    Hsieh MJ; Weng CC; Lin YC; Wu CC; Chen LT; Cheng KH
    Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33924999
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Energy sensing and cancer: LKB1 function and lessons learnt from Peutz-Jeghers syndrome.
    Shorning BY; Clarke AR
    Semin Cell Dev Biol; 2016 Apr; 52():21-9. PubMed ID: 26877140
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.
    Corradetti MN; Inoki K; Bardeesy N; DePinho RA; Guan KL
    Genes Dev; 2004 Jul; 18(13):1533-8. PubMed ID: 15231735
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The molecular mechanisms that underlie the tumor suppressor function of LKB1.
    Fan D; Ma C; Zhang H
    Acta Biochim Biophys Sin (Shanghai); 2009 Feb; 41(2):97-107. PubMed ID: 19204826
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Controlling the master-upstream regulation of the tumor suppressor LKB1.
    Kullmann L; Krahn MP
    Oncogene; 2018 Jun; 37(23):3045-3057. PubMed ID: 29540834
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of the LKB1/AMPK pathway in tumor invasion and metastasis of cancer cells (Review).
    Li N; Huang D; Lu N; Luo L
    Oncol Rep; 2015 Dec; 34(6):2821-6. PubMed ID: 26398719
    [TBL] [Abstract][Full Text] [Related]  

  • 13. LKB1 and KEAP1/NRF2 Pathways Cooperatively Promote Metabolic Reprogramming with Enhanced Glutamine Dependence in
    Galan-Cobo A; Sitthideatphaiboon P; Qu X; Poteete A; Pisegna MA; Tong P; Chen PH; Boroughs LK; Rodriguez MLM; Zhang W; Parlati F; Wang J; Gandhi V; Skoulidis F; DeBerardinis RJ; Minna JD; Heymach JV
    Cancer Res; 2019 Jul; 79(13):3251-3267. PubMed ID: 31040157
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the LKB1 tumor suppressor.
    Zhao RX; Xu ZX
    Curr Drug Targets; 2014 Jan; 15(1):32-52. PubMed ID: 24387336
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression.
    Ma Y; Zhang G; Fu X; Xia O; Zhan C; Li L; Wang Z; Wu B
    Oncol Rep; 2010 Jun; 23(6):1569-76. PubMed ID: 20428811
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LKB1, the multitasking tumour suppressor kinase.
    Marignani PA
    J Clin Pathol; 2005 Jan; 58(1):15-9. PubMed ID: 15623475
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms.
    Hezel AF; Gurumurthy S; Granot Z; Swisa A; Chu GC; Bailey G; Dor Y; Bardeesy N; Depinho RA
    Mol Cell Biol; 2008 Apr; 28(7):2414-25. PubMed ID: 18227155
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death.
    Karuman P; Gozani O; Odze RD; Zhou XC; Zhu H; Shaw R; Brien TP; Bozzuto CD; Ooi D; Cantley LC; Yuan J
    Mol Cell; 2001 Jun; 7(6):1307-19. PubMed ID: 11430832
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Peutz-Jeghers LKB1 mutants fail to activate GSK-3beta, preventing it from inhibiting Wnt signaling.
    Lin-Marq N; Borel C; Antonarakis SE
    Mol Genet Genomics; 2005 Apr; 273(2):184-96. PubMed ID: 15731909
    [TBL] [Abstract][Full Text] [Related]  

  • 20. mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome.
    Shackelford DB; Vasquez DS; Corbeil J; Wu S; Leblanc M; Wu CL; Vera DR; Shaw RJ
    Proc Natl Acad Sci U S A; 2009 Jul; 106(27):11137-42. PubMed ID: 19541609
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.