130 related articles for article (PubMed ID: 33279247)
1. 5-[Aryloxypyridyl (or nitrophenyl)]-4H-1,2,4-triazoles as novel flexible benzodiazepine analogues: Synthesis, receptor binding affinity and lipophilicity-dependent anti-seizure onset of action.
Navidpour L; Shabani S; Heidari A; Bashiri M; Ebrahim-Habibi A; Shahhosseini S; Shafaroodi H; Abbas Tabatabai S; Toolabi M
Bioorg Chem; 2021 Jan; 106():104504. PubMed ID: 33279247
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, receptor affinity and effect on pentylenetetrazole-induced seizure threshold of novel benzodiazepine analogues: 3-Substituted 5-(2-phenoxybenzyl)-4H-1,2,4-triazoles and 2-amino-5-(phenoxybenzyl)-1,3,4-oxadiazoles.
Mashayekh S; Rahmanipour N; Mahmoodi B; Ahmadi F; Motaharian D; Shahhosseini S; Shafaroodi H; Banafshe HR; Shafiee A; Navidpour L
Bioorg Med Chem; 2014 Mar; 22(6):1929-37. PubMed ID: 24530225
[TBL] [Abstract][Full Text] [Related]
3. Novel fused 1,2,3-triazolo-benzodiazepine derivatives as potent anticonvulsant agents: design, synthesis, in vivo, and in silico evaluations.
Shafie A; Mohammadi-Khanaposhtani M; Asadi M; Rahimi N; Ranjbar PR; Ghasemi JB; Larijani B; Mahdavi M; Shafaroodi H; Dehpour AR
Mol Divers; 2020 Feb; 24(1):179-189. PubMed ID: 30895449
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, and pharmacological evaluation of novel 1,2,4-triazol-3-amine derivatives as potential agonists of GABA
Jahani R; Reza Abtahi S; Nematpour M; Fasihi Dastjerdi H; Chamanara M; Hami Z; Paknejad B
Bioorg Chem; 2020 Nov; 104():104212. PubMed ID: 32916390
[TBL] [Abstract][Full Text] [Related]
5. Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil.
Löscher W; Hönack D
Br J Pharmacol; 1994 Dec; 113(4):1349-57. PubMed ID: 7889291
[TBL] [Abstract][Full Text] [Related]
6. Discovery of 7-alkyloxy- [1,2,4] triazolo[1,5-a] pyrimidine derivatives as selective positive modulators of GABA
Wu J; Hou Z; Wang Y; Chen L; Lian C; Meng Q; Zhang C; Li X; Huang L; Yu H
Bioorg Chem; 2022 Feb; 119():105565. PubMed ID: 34929519
[TBL] [Abstract][Full Text] [Related]
7. Novel agonists of benzodiazepine receptors: design, synthesis, binding assay and pharmacological evaluation of 1,2,4-triazolo[1,5-a]pyrimidinone and 3-amino-1,2,4-triazole derivatives.
Faizi M; Dabirian S; Tajali H; Ahmadi F; Zavareh ER; Shahhosseini S; Tabatabai SA
Bioorg Med Chem; 2015 Feb; 23(3):480-7. PubMed ID: 25564376
[TBL] [Abstract][Full Text] [Related]
8. Studies on the anticonvulsant activity of 4-alkyl-1,2,4-triazole-3-thiones and their effect on GABAergic system.
Plech T; Kaproń B; Luszczki JJ; Paneth A; Siwek A; Kołaczkowski M; Żołnierek M; Nowak G
Eur J Med Chem; 2014 Oct; 86():690-9. PubMed ID: 25226229
[TBL] [Abstract][Full Text] [Related]
9. 5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents.
Kane JM; Staeger MA; Dalton CR; Miller FP; Dudley MW; Ogden AM; Kehne JH; Ketteler HJ; McCloskey TC; Senyah Y
J Med Chem; 1994 Jan; 37(1):125-32. PubMed ID: 8289185
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and evaluation of anticonvulsant activities of benzoxazole derivatives containing the 1,2,4-triazolone moiety.
Song MX; Huang Y; Wang S; Wang ZT; Deng XQ
Arch Pharm (Weinheim); 2019 Aug; 352(8):e1800313. PubMed ID: 31330092
[TBL] [Abstract][Full Text] [Related]
11. Design and synthesis of 4H-3-(2-phenoxy)phenyl-1,2,4-triazole derivatives as benzodiazepine receptor agonists.
Akbarzadeh T; Tabatabai SA; Khoshnoud MJ; Shafaghi B; Shafiee A
Bioorg Med Chem; 2003 Mar; 11(5):769-73. PubMed ID: 12538007
[TBL] [Abstract][Full Text] [Related]
12. Acid-catalysed hydrolysis and benzodiazepine-like properties of 5-(dialkylamino)- and 5-(alkylthio)-substituted 8-chloro-6-phenyl-6H-[1,2,4]triazolol[4,3-a][1,5]benzodiazepines in mice.
Caccia S; Grossi G; Fracasso C; Nacca A; Cagnotto A; Mennini T; Ghia M; Roma G
J Pharm Pharmacol; 1998 Jul; 50(7):723-8. PubMed ID: 9720620
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and evaluation of pharmacological properties of novel annelated 2,3-benzodiazepine derivatives.
Gitto R; Orlando V; Quartarone S; De Sarro G; De Sarro A; Russo E; Ferreri G; Chimirri A
J Med Chem; 2003 Aug; 46(17):3758-61. PubMed ID: 12904081
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and Evaluation of the Anticonvulsant Activities of 4-(2-(Alkylthio)benzo[d]oxazol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-ones.
Song MX; Wang ZY; He SH; Yu SW; Chen SL; Guo DF; Zhao WH; Deng XQ
Molecules; 2018 Mar; 23(4):. PubMed ID: 29587394
[TBL] [Abstract][Full Text] [Related]
15. Azirino[1, 2-d][1, 4]benzodiazepine derivatives and related 1,4-benzodiazepines as anticonvulsant agents in DBA/2 mice.
De Sarro G; Chimirri A; Zappala M; Guisti P; Lipartiti M; De Sarro A
Gen Pharmacol; 1996 Oct; 27(7):1155-62. PubMed ID: 8981061
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and Pharmacological Evaluation of New 3,4-Dihydroisoquinolin Derivatives Containing Heterocycle as Potential Anticonvulsant Agents.
Zhang HJ; Shen QK; Jin CM; Quan ZS
Molecules; 2016 Nov; 21(12):. PubMed ID: 27916842
[TBL] [Abstract][Full Text] [Related]
17. Antiseizure activity of novel gamma-aminobutyric acid (A) receptor subtype-selective benzodiazepine analogues in mice and rat models.
Rivas FM; Stables JP; Murphree L; Edwankar RV; Edwankar CR; Huang S; Jain HD; Zhou H; Majumder S; Sankar S; Roth BL; Ramerstorfer J; Furtmüller R; Sieghart W; Cook JM
J Med Chem; 2009 Apr; 52(7):1795-8. PubMed ID: 19275170
[TBL] [Abstract][Full Text] [Related]
18. Imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepines as potent and highly selective GABAA alpha5 inverse agonists with potential for the treatment of cognitive dysfunction.
Buettelmann B; Ballard TM; Gasser R; Fischer H; Hernandez MC; Knoflach F; Knust H; Stadler H; Thomas AW; Trube G
Bioorg Med Chem Lett; 2009 Oct; 19(20):5958-61. PubMed ID: 19740657
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and Neurotropic Activity of New Heterocyclic Systems: Pyridofuro[3,2-
Sirakanyan SN; Spinelli D; Geronikaki A; Kartsev V; Hakobyan EK; Petrou A; Paronikyan RG; Nazaryan IM; Akopyan HH; Hovakimyan AA
Molecules; 2021 Jun; 26(11):. PubMed ID: 34205930
[TBL] [Abstract][Full Text] [Related]
20. The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA alpha5 inverse agonists for the treatment of cognitive dysfunction.
Knust H; Achermann G; Ballard T; Buettelmann B; Gasser R; Fischer H; Hernandez MC; Knoflach F; Koblet A; Stadler H; Thomas AW; Trube G; Waldmeier P
Bioorg Med Chem Lett; 2009 Oct; 19(20):5940-4. PubMed ID: 19762240
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]