210 related articles for article (PubMed ID: 33283949)
1. Targeting H3K9 methyltransferase G9a and its related molecule GLP as a potential therapeutic strategy for cancer.
Rahman Z; Bazaz MR; Devabattula G; Khan MA; Godugu C
J Biochem Mol Toxicol; 2021 Mar; 35(3):e22674. PubMed ID: 33283949
[TBL] [Abstract][Full Text] [Related]
2. Targeting EHMT2/ G9a for cancer therapy: Progress and perspective.
Jan S; Dar MI; Wani R; Sandey J; Mushtaq I; Lateef S; Syed SH
Eur J Pharmacol; 2021 Feb; 893():173827. PubMed ID: 33347828
[TBL] [Abstract][Full Text] [Related]
3. Discovery of the First-in-Class G9a/GLP PROTAC Degrader.
Velez J; Han Y; Yim H; Yang P; Deng Z; Park KS; Kabir M; Kaniskan HÜ; Xiong Y; Jin J
J Med Chem; 2024 Apr; 67(8):6397-6409. PubMed ID: 38602846
[TBL] [Abstract][Full Text] [Related]
4. Recent progress in histone methyltransferase (G9a) inhibitors as anticancer agents.
Cao H; Li L; Yang D; Zeng L; Yewei X; Yu B; Liao G; Chen J
Eur J Med Chem; 2019 Oct; 179():537-546. PubMed ID: 31276898
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II).
Lenstra DC; Al Temimi AHK; Mecinović J
Bioorg Med Chem Lett; 2018 Apr; 28(7):1234-1238. PubMed ID: 29519735
[TBL] [Abstract][Full Text] [Related]
6. Heterodimerization of H3K9 histone methyltransferases G9a and GLP activates methyl reading and writing capabilities.
Sanchez NA; Kallweit LM; Trnka MJ; Clemmer CL; Al-Sady B
J Biol Chem; 2021 Nov; 297(5):101276. PubMed ID: 34619147
[TBL] [Abstract][Full Text] [Related]
7. The zinc finger proteins ZNF644 and WIZ regulate the G9a/GLP complex for gene repression.
Bian C; Chen Q; Yu X
Elife; 2015 Mar; 4():. PubMed ID: 25789554
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of G9a by a small molecule inhibitor, UNC0642, induces apoptosis of human bladder cancer cells.
Cao YP; Sun JY; Li MQ; Dong Y; Zhang YH; Yan J; Huang RM; Yan X
Acta Pharmacol Sin; 2019 Aug; 40(8):1076-1084. PubMed ID: 30765842
[TBL] [Abstract][Full Text] [Related]
9. MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Chang Y; Sun L; Kokura K; Horton JR; Fukuda M; Espejo A; Izumi V; Koomen JM; Bedford MT; Zhang X; Shinkai Y; Fang J; Cheng X
Nat Commun; 2011 Nov; 2():533. PubMed ID: 22086334
[TBL] [Abstract][Full Text] [Related]
10. Depletion of G9a gene induces cell apoptosis in human gastric carcinoma.
Lin X; Huang Y; Zou Y; Chen X; Ma X
Oncol Rep; 2016 May; 35(5):3041-9. PubMed ID: 27081761
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of the G9a/GLP histone methyltransferase complex modulates anxiety-related behavior in mice.
Wang DY; Kosowan J; Samsom J; Leung L; Zhang KL; Li YX; Xiong Y; Jin J; Petronis A; Oh G; Wong AHC
Acta Pharmacol Sin; 2018 May; 39(5):866-874. PubMed ID: 29417943
[TBL] [Abstract][Full Text] [Related]
12. H3K9 methyltransferase G9a and the related molecule GLP.
Shinkai Y; Tachibana M
Genes Dev; 2011 Apr; 25(8):781-8. PubMed ID: 21498567
[TBL] [Abstract][Full Text] [Related]
13. H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM.
Chen MW; Hua KT; Kao HJ; Chi CC; Wei LH; Johansson G; Shiah SG; Chen PS; Jeng YM; Cheng TY; Lai TC; Chang JS; Jan YH; Chien MH; Yang CJ; Huang MS; Hsiao M; Kuo ML
Cancer Res; 2010 Oct; 70(20):7830-40. PubMed ID: 20940408
[TBL] [Abstract][Full Text] [Related]
14. Insights for the design of protein lysine methyltransferase G9a inhibitors.
Charles MRC; Dhayalan A; Hsieh HP; Coumar MS
Future Med Chem; 2019 May; 11(9):993-1014. PubMed ID: 31141392
[TBL] [Abstract][Full Text] [Related]
15. Histone methyltransferase G9a promotes liver cancer development by epigenetic silencing of tumor suppressor gene RARRES3.
Wei L; Chiu DK; Tsang FH; Law CT; Cheng CL; Au SL; Lee JM; Wong CC; Ng IO; Wong CM
J Hepatol; 2017 Oct; 67(4):758-769. PubMed ID: 28532996
[TBL] [Abstract][Full Text] [Related]
16. FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes.
Kang J; Shin SH; Yoon H; Huh J; Shin HW; Chun YS; Park JW
Cancer Res; 2018 Mar; 78(5):1184-1199. PubMed ID: 29259012
[TBL] [Abstract][Full Text] [Related]
17. G9a - An Appealing Antineoplastic Target.
Chen WL; Sun HP; Li DD; Wang ZH; You QD; Guo XK
Curr Cancer Drug Targets; 2017; 17(6):555-568. PubMed ID: 27174055
[TBL] [Abstract][Full Text] [Related]
18. Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase.
Xiong Y; Li F; Babault N; Dong A; Zeng H; Wu H; Chen X; Arrowsmith CH; Brown PJ; Liu J; Vedadi M; Jin J
J Med Chem; 2017 Mar; 60(5):1876-1891. PubMed ID: 28135087
[TBL] [Abstract][Full Text] [Related]
19. Discovery of novel histone lysine methyltransferase G9a/GLP (EHMT2/1) inhibitors: Design, synthesis, and structure-activity relationships of 2,4-diamino-6-methylpyrimidines.
Katayama K; Ishii K; Tsuda E; Yotsumoto K; Hiramoto K; Suzuki M; Yasumatsu I; Igarashi W; Torihata M; Ishiyama T; Katagiri T
Bioorg Med Chem Lett; 2020 Oct; 30(20):127475. PubMed ID: 32781218
[TBL] [Abstract][Full Text] [Related]
20. The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia.
Pappano WN; Guo J; He Y; Ferguson D; Jagadeeswaran S; Osterling DJ; Gao W; Spence JK; Pliushchev M; Sweis RF; Buchanan FG; Michaelides MR; Shoemaker AR; Tse C; Chiang GG
PLoS One; 2015; 10(7):e0131716. PubMed ID: 26147105
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
