These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

485 related articles for article (PubMed ID: 33283990)

  • 1. Post-Transcriptional Genetic Silencing of
    Esrick EB; Lehmann LE; Biffi A; Achebe M; Brendel C; Ciuculescu MF; Daley H; MacKinnon B; Morris E; Federico A; Abriss D; Boardman K; Khelladi R; Shaw K; Negre H; Negre O; Nikiforow S; Ritz J; Pai SY; London WB; Dansereau C; Heeney MM; Armant M; Manis JP; Williams DA
    N Engl J Med; 2021 Jan; 384(3):205-215. PubMed ID: 33283990
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells.
    Zhang Y; Paikari A; Sumazin P; Ginter Summarell CC; Crosby JR; Boerwinkle E; Weiss MJ; Sheehan VA
    Blood; 2018 Jul; 132(3):321-333. PubMed ID: 29884740
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.
    Xu J; Peng C; Sankaran VG; Shao Z; Esrick EB; Chong BG; Ippolito GC; Fujiwara Y; Ebert BL; Tucker PW; Orkin SH
    Science; 2011 Nov; 334(6058):993-6. PubMed ID: 21998251
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sustained fetal hemoglobin induction in vivo is achieved by
    Uchida N; Ferrara F; Drysdale CM; Yapundich M; Gamer J; Nassehi T; DiNicola J; Shibata Y; Wielgosz M; Kim YS; Bauler M; Throm RE; Haro-Mora JJ; Demirci S; Bonifacino AC; Krouse AE; Linde NS; Donahue RE; Ryu B; Tisdale JF
    Sci Transl Med; 2021 Apr; 13(591):. PubMed ID: 33910976
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acyclovir induces fetal hemoglobin via downregulation of γ-globin repressors, BCL11A and SOX6 trans-acting factors.
    Ali H; Khan F; Ghulam Musharraf S
    Biochem Pharmacol; 2021 Aug; 190():114612. PubMed ID: 34010599
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Association between BCL11A, HSB1L-MYB, and XmnI γG-158 (C/T) gene polymorphism and hemoglobin F level in Egyptian sickle cell disease patients.
    El-Ghamrawy M; Yassa ME; Tousson AMS; El-Hady MA; Mikhaeil E; Mohamed NB; Khorshied MM
    Ann Hematol; 2020 Oct; 99(10):2279-2288. PubMed ID: 32772141
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fetal hemoglobin in sickle cell anemia.
    Steinberg MH
    Blood; 2020 Nov; 136(21):2392-2400. PubMed ID: 32808012
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel human gamma-globin gene vector for genetic correction of sickle cell anemia in a humanized sickle mouse model: critical determinants for successful correction.
    Perumbeti A; Higashimoto T; Urbinati F; Franco R; Meiselman HJ; Witte D; Malik P
    Blood; 2009 Aug; 114(6):1174-85. PubMed ID: 19474450
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling.
    De Souza DC; Hebert N; Esrick EB; Ciuculescu MF; Archer NM; Armant M; Audureau É; Brendel C; Di Caprio G; Galactéros F; Liu D; McCabe A; Morris E; Schonbrun E; Williams D; Wood DK; Williams DA; Bartolucci P; Higgins JM
    Nat Commun; 2023 Sep; 14(1):5850. PubMed ID: 37730674
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
    Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
    Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional Repressor BCL11A in Erythroid Cells.
    Zheng G; Orkin SH
    Adv Exp Med Biol; 2024; 1459():199-215. PubMed ID: 39017845
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.
    Wilber A; Hargrove PW; Kim YS; Riberdy JM; Sankaran VG; Papanikolaou E; Georgomanoli M; Anagnou NP; Orkin SH; Nienhuis AW; Persons DA
    Blood; 2011 Mar; 117(10):2817-26. PubMed ID: 21156846
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CRISPR-Cas9 Editing of the
    Sharma A; Boelens JJ; Cancio M; Hankins JS; Bhad P; Azizy M; Lewandowski A; Zhao X; Chitnis S; Peddinti R; Zheng Y; Kapoor N; Ciceri F; Maclachlan T; Yang Y; Liu Y; Yuan J; Naumann U; Yu VWC; Stevenson SC; De Vita S; LaBelle JL
    N Engl J Med; 2023 Aug; 389(9):820-832. PubMed ID: 37646679
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat β-hemoglobinopathies.
    Liu B; Brendel C; Vinjamur DS; Zhou Y; Harris C; McGuinness M; Manis JP; Bauer DE; Xu H; Williams DA
    Mol Ther; 2022 Aug; 30(8):2693-2708. PubMed ID: 35526095
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparative targeting analysis of KLF1, BCL11A, and HBG1/2 in CD34
    Lamsfus-Calle A; Daniel-Moreno A; Antony JS; Epting T; Heumos L; Baskaran P; Admard J; Casadei N; Latifi N; Siegmund DM; Kormann MSD; Handgretinger R; Mezger M
    Sci Rep; 2020 Jun; 10(1):10133. PubMed ID: 32576837
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Correction of murine sickle cell disease using gamma-globin lentiviral vectors to mediate high-level expression of fetal hemoglobin.
    Pestina TI; Hargrove PW; Jay D; Gray JT; Boyd KM; Persons DA
    Mol Ther; 2009 Feb; 17(2):245-52. PubMed ID: 19050697
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.
    Brendel C; Guda S; Renella R; Bauer DE; Canver MC; Kim YJ; Heeney MM; Klatt D; Fogel J; Milsom MD; Orkin SH; Gregory RI; Williams DA
    J Clin Invest; 2016 Oct; 126(10):3868-3878. PubMed ID: 27599293
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Novel Role of the B-Cell Lymphoma/Leukemia 11A (BCL11A) Gene in β-Thalassaemia Treatment.
    Mahmoud Ahmed NH; Lai MI
    Cardiovasc Hematol Disord Drug Targets; 2023; 22(4):226-236. PubMed ID: 36734897
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cilostazol-mediated reversion of γ-globin silencing is associated with a high level of HbF production: A potential therapeutic candidate for β-globin disorders.
    Ali H; Khan F; Musharraf SG
    Biomed Pharmacother; 2021 Oct; 142():112058. PubMed ID: 34426256
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Highly efficient therapeutic gene editing of human hematopoietic stem cells.
    Wu Y; Zeng J; Roscoe BP; Liu P; Yao Q; Lazzarotto CR; Clement K; Cole MA; Luk K; Baricordi C; Shen AH; Ren C; Esrick EB; Manis JP; Dorfman DM; Williams DA; Biffi A; Brugnara C; Biasco L; Brendel C; Pinello L; Tsai SQ; Wolfe SA; Bauer DE
    Nat Med; 2019 May; 25(5):776-783. PubMed ID: 30911135
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.