BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

415 related articles for article (PubMed ID: 33301444)

  • 1. TDP-43 mutations link Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage.
    Giannini M; Bayona-Feliu A; Sproviero D; Barroso SI; Cereda C; Aguilera A
    PLoS Genet; 2020 Dec; 16(12):e1009260. PubMed ID: 33301444
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.
    Mitra J; Guerrero EN; Hegde PM; Liachko NF; Wang H; Vasquez V; Gao J; Pandey A; Taylor JP; Kraemer BC; Wu P; Boldogh I; Garruto RM; Mitra S; Rao KS; Hegde ML
    Proc Natl Acad Sci U S A; 2019 Mar; 116(10):4696-4705. PubMed ID: 30770445
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
    Guerrero EN; Mitra J; Wang H; Rangaswamy S; Hegde PM; Basu P; Rao KS; Hegde ML
    Hum Mol Genet; 2019 Aug; 28(15):2459-2476. PubMed ID: 31067307
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TDP-43 dysfunction results in R-loop accumulation and DNA replication defects.
    Wood M; Quinet A; Lin YL; Davis AA; Pasero P; Ayala YM; Vindigni A
    J Cell Sci; 2020 Oct; 133(20):. PubMed ID: 32989039
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients.
    Yamashita T; Kwak S
    Brain Res; 2014 Oct; 1584():28-38. PubMed ID: 24355598
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis.
    MacNair L; Xiao S; Miletic D; Ghani M; Julien JP; Keith J; Zinman L; Rogaeva E; Robertson J
    Brain; 2016 Jan; 139(Pt 1):86-100. PubMed ID: 26525917
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [The implications of TDP-43 mutations in pathogenesis of amyotrophic lateral sclerosis].
    Ishihara T; Yokoseki A; Nishizawa M; Takahashi H; Onodera O
    Brain Nerve; 2009 Nov; 61(11):1301-7. PubMed ID: 19938687
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutation in the RRM2 domain of TDP-43 in Amyotrophic Lateral Sclerosis with rapid progression associated with ubiquitin positive aggregates in cultured motor neurons.
    Maurel C; Madji-Hounoum B; Thepault RA; Marouillat S; Brulard C; Danel-Brunaud V; Camdessanche JP; Blasco H; Corcia P; Andres CR; Vourc'h P
    Amyotroph Lateral Scler Frontotemporal Degener; 2018 Feb; 19(1-2):149-151. PubMed ID: 28705014
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro.
    Penndorf D; Tadić V; Witte OW; Grosskreutz J; Kretz A
    PLoS One; 2017; 12(8):e0183684. PubMed ID: 28832631
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
    Mackenzie IR; Bigio EH; Ince PG; Geser F; Neumann M; Cairns NJ; Kwong LK; Forman MS; Ravits J; Stewart H; Eisen A; McClusky L; Kretzschmar HA; Monoranu CM; Highley JR; Kirby J; Siddique T; Shaw PJ; Lee VM; Trojanowski JQ
    Ann Neurol; 2007 May; 61(5):427-34. PubMed ID: 17469116
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
    Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
    Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Commentary on TDP-43 and DNA Damage Response in Amyotrophic Lateral Sclerosis.
    Mitra J; Hegde ML
    J Exp Neurosci; 2019; 13():1179069519880166. PubMed ID: 31656396
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Clinical and pathological spectrum of TDP-43 associated ALS].
    Onodera O; Yokoseki A; Tan CF; Ishihara T; Nishiira Y; Toyoshima Y; Kakita A; Nishizawa M; Takahashi H
    Rinsho Shinkeigaku; 2010 Nov; 50(11):940-2. PubMed ID: 21921519
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4.
    Kannan A; Cuartas J; Gangwani P; Branzei D; Gangwani L
    Brain; 2022 Sep; 145(9):3072-3094. PubMed ID: 35045161
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TDP-43: a DNA and RNA binding protein with roles in neurodegenerative diseases.
    Warraich ST; Yang S; Nicholson GA; Blair IP
    Int J Biochem Cell Biol; 2010 Oct; 42(10):1606-9. PubMed ID: 20601083
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Monocytes of patients with amyotrophic lateral sclerosis linked to gene mutations display altered TDP-43 subcellular distribution.
    De Marco G; Lomartire A; Calvo A; Risso A; De Luca E; Mostert M; Mandrioli J; Caponnetto C; Borghero G; Manera U; Canosa A; Moglia C; Restagno G; Fini N; Tarella C; Giordana MT; Rinaudo MT; Chiò A
    Neuropathol Appl Neurobiol; 2017 Feb; 43(2):133-153. PubMed ID: 27178390
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.
    Deshaies JE; Shkreta L; Moszczynski AJ; Sidibé H; Semmler S; Fouillen A; Bennett ER; Bekenstein U; Destroismaisons L; Toutant J; Delmotte Q; Volkening K; Stabile S; Aulas A; Khalfallah Y; Soreq H; Nanci A; Strong MJ; Chabot B; Vande Velde C
    Brain; 2018 May; 141(5):1320-1333. PubMed ID: 29562314
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Molecular link between inefficient GluA2 RNA editing and TDP-43 pathology in ALS motor neurons].
    Kwak S
    Brain Nerve; 2012 May; 64(5):549-56. PubMed ID: 22570068
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lack of TDP-43 abnormalities in mutant SOD1 transgenic mice shows disparity with ALS.
    Robertson J; Sanelli T; Xiao S; Yang W; Horne P; Hammond R; Pioro EP; Strong MJ
    Neurosci Lett; 2007 Jun; 420(2):128-32. PubMed ID: 17543992
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TDP-43 mutation in familial amyotrophic lateral sclerosis.
    Yokoseki A; Shiga A; Tan CF; Tagawa A; Kaneko H; Koyama A; Eguchi H; Tsujino A; Ikeuchi T; Kakita A; Okamoto K; Nishizawa M; Takahashi H; Onodera O
    Ann Neurol; 2008 Apr; 63(4):538-42. PubMed ID: 18438952
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.