201 related articles for article (PubMed ID: 33303699)
1. Distinct Uptake Kinetics of Alzheimer Disease Amyloid-
Sharda N; Ahlschwede KM; Curran GL; Lowe VJ; Kandimalla KK
J Pharmacol Exp Ther; 2021 Mar; 376(3):482-490. PubMed ID: 33303699
[TBL] [Abstract][Full Text] [Related]
2. Amyloid-Beta Peptides 40 and 42 Employ Distinct Molecular Pathways for Cell Entry and Intracellular Transit at the Blood-Brain Barrier Endothelium.
Wang Z; Sharda N; Omtri RS; Li L; Kandimalla KK
Mol Pharmacol; 2023 Nov; 104(5):203-213. PubMed ID: 37541759
[TBL] [Abstract][Full Text] [Related]
3. Insulin differentially affects the distribution kinetics of amyloid beta 40 and 42 in plasma and brain.
Swaminathan SK; Ahlschwede KM; Sarma V; Curran GL; Omtri RS; Decklever T; Lowe VJ; Poduslo JF; Kandimalla KK
J Cereb Blood Flow Metab; 2018 May; 38(5):904-918. PubMed ID: 28569090
[TBL] [Abstract][Full Text] [Related]
4. Semimechanistic Population Pharmacokinetic Modeling to Investigate Amyloid Beta Trafficking and Accumulation at the BBB Endothelium.
Wang Z; Sharda N; Curran GL; Li L; Lowe VJ; Kandimalla KK
Mol Pharm; 2021 Nov; 18(11):4148-4161. PubMed ID: 34664956
[TBL] [Abstract][Full Text] [Related]
5. High-Density Lipoprotein Mimetic Peptide 4F Efficiently Crosses the Blood-Brain Barrier and Modulates Amyloid-
Swaminathan SK; Zhou AL; Ahlschwede KM; Curran GL; Lowe VJ; Li L; Kandimalla KK
J Pharmacol Exp Ther; 2020 Nov; 375(2):308-316. PubMed ID: 32778535
[TBL] [Abstract][Full Text] [Related]
6. Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling.
Qosa H; Abuasal BS; Romero IA; Weksler B; Couraud PO; Keller JN; Kaddoumi A
Neuropharmacology; 2014 Apr; 79():668-78. PubMed ID: 24467845
[TBL] [Abstract][Full Text] [Related]
7. Insulin Signaling Differentially Regulates the Trafficking of Insulin and Amyloid Beta Peptides at the Blood-Brain Barrier.
Zhou AL; Swaminathan SK; Salian VS; Wang L; Curran GL; Min HK; Lowe VJ; Kandimalla KK
Mol Pharm; 2024 May; 21(5):2176-2186. PubMed ID: 38625027
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
Shackleton B; Crawford F; Bachmeier C
Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
[TBL] [Abstract][Full Text] [Related]
9. Traffic jam at the blood-brain barrier promotes greater accumulation of Alzheimer's disease amyloid-β proteins in the cerebral vasculature.
Agyare EK; Leonard SR; Curran GL; Yu CC; Lowe VJ; Paravastu AK; Poduslo JF; Kandimalla KK
Mol Pharm; 2013 May; 10(5):1557-65. PubMed ID: 23249146
[TBL] [Abstract][Full Text] [Related]
10. Abeta peptides can enter the brain through a defective blood-brain barrier and bind selectively to neurons.
Clifford PM; Zarrabi S; Siu G; Kinsler KJ; Kosciuk MC; Venkataraman V; D'Andrea MR; Dinsmore S; Nagele RG
Brain Res; 2007 Apr; 1142():223-36. PubMed ID: 17306234
[TBL] [Abstract][Full Text] [Related]
11. Differences in the cellular uptake and intracellular itineraries of amyloid beta proteins 40 and 42: ramifications for the Alzheimer's drug discovery.
Omtri RS; Davidson MW; Arumugam B; Poduslo JF; Kandimalla KK
Mol Pharm; 2012 Jul; 9(7):1887-97. PubMed ID: 22574751
[TBL] [Abstract][Full Text] [Related]
12. Mixed oligomers and monomeric amyloid-β disrupts endothelial cells integrity and reduces monomeric amyloid-β transport across hCMEC/D3 cell line as an in vitro blood-brain barrier model.
Qosa H; LeVine H; Keller JN; Kaddoumi A
Biochim Biophys Acta; 2014 Sep; 1842(9):1806-15. PubMed ID: 24997450
[TBL] [Abstract][Full Text] [Related]
13. Age-Dependent Changes in the Plasma and Brain Pharmacokinetics of Amyloid-β Peptides and Insulin.
Zhou AL; Sharda N; Sarma VV; Ahlschwede KM; Curran GL; Tang X; Poduslo JF; Kalari KR; Lowe VJ; Kandimalla KK
J Alzheimers Dis; 2022; 85(3):1031-1044. PubMed ID: 34924382
[TBL] [Abstract][Full Text] [Related]
14. Distinct Effects of Beta-Amyloid, Its Isomerized and Phosphorylated Forms on the Redox Status and Mitochondrial Functioning of the Blood-Brain Barrier Endothelium.
Petrovskaya AV; Tverskoi AM; Barykin EP; Varshavskaya KB; Dalina AA; Mitkevich VA; Makarov AA; Petrushanko IY
Int J Mol Sci; 2022 Dec; 24(1):. PubMed ID: 36613623
[TBL] [Abstract][Full Text] [Related]
15. Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier.
Kisler K; Sagare AP; Lazic D; Bazzi S; Lawson E; Hsu CJ; Wang Y; Ramanathan A; Nelson AR; Zhao Z; Zlokovic BV
Mol Neurodegener; 2023 Jan; 18(1):7. PubMed ID: 36707892
[TBL] [Abstract][Full Text] [Related]
16. Detection of amyloid plaques by radioligands for Abeta40 and Abeta42: potential imaging agents in Alzheimer's patients.
Kung MP; Skovronsky DM; Hou C; Zhuang ZP; Gur TL; Zhang B; Trojanowski JQ; Lee VM; Kung HF
J Mol Neurosci; 2003 Feb; 20(1):15-24. PubMed ID: 12663930
[TBL] [Abstract][Full Text] [Related]
17. Blood-brain barrier integrity impacts the use of plasma amyloid-β as a proxy of brain amyloid-β pathology.
Bellaver B; Puig-Pijoan A; Ferrari-Souza JP; Leffa DT; Lussier FZ; Ferreira PCL; Tissot C; Povala G; Therriault J; Benedet AL; Ashton NJ; Servaes S; Chamoun M; Stevenson J; Rahmouni N; Vermeiren M; Macedo AC; Fernández-Lebrero A; García-Escobar G; Navalpotro-Gómez I; Lopez O; Tudorascu DL; Cohen A; Villemagne VL; Klunk WE; Gauthier S; Zimmer ER; Karikari TK; Blennow K; Zetterberg H; Suárez-Calvet M; Rosa-Neto P; Pascoal TA
Alzheimers Dement; 2023 Sep; 19(9):3815-3825. PubMed ID: 36919582
[TBL] [Abstract][Full Text] [Related]
18. The coexistence of an equal amount of Alzheimer's amyloid-β 40 and 42 forms structurally stable and toxic oligomers through a distinct pathway.
Chang YJ; Chen YR
FEBS J; 2014 Jun; 281(11):2674-87. PubMed ID: 24720730
[TBL] [Abstract][Full Text] [Related]
19. New Evidence for P-gp-Mediated Export of Amyloid-β PEPTIDES in Molecular, Blood-Brain Barrier and Neuronal Models.
Chai AB; Hartz AMS; Gao X; Yang A; Callaghan R; Gelissen IC
Int J Mol Sci; 2020 Dec; 22(1):. PubMed ID: 33383667
[TBL] [Abstract][Full Text] [Related]
20. Alzheimer's amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood-brain barrier integrity, and angiogenesis.
Parodi-Rullán R; Ghiso J; Cabrera E; Rostagno A; Fossati S
Aging Cell; 2020 Nov; 19(11):e13258. PubMed ID: 33155752
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
