198 related articles for article (PubMed ID: 33303821)
1. Saturated fatty acids induce insulin resistance in podocytes through inhibition of IRS1 via activation of both IKKβ and mTORC1.
Denhez B; Rousseau M; Spino C; Dancosst DA; Dumas MÈ; Guay A; Lizotte F; Geraldes P
Sci Rep; 2020 Dec; 10(1):21628. PubMed ID: 33303821
[TBL] [Abstract][Full Text] [Related]
2. Fatty acids are novel nutrient factors to regulate mTORC1 lysosomal localization and apoptosis in podocytes.
Yasuda M; Tanaka Y; Kume S; Morita Y; Chin-Kanasaki M; Araki H; Isshiki K; Araki S; Koya D; Haneda M; Kashiwagi A; Maegawa H; Uzu T
Biochim Biophys Acta; 2014 Jul; 1842(7):1097-108. PubMed ID: 24726883
[TBL] [Abstract][Full Text] [Related]
3. Reduction of DUSP4 contributes to podocytes oxidative stress, insulin resistance and diabetic nephropathy.
Rousseau M; Denhez B; Spino C; Lizotte F; Guay A; Côté AM; Burger D; Geraldes P
Biochem Biophys Res Commun; 2022 Oct; 624():127-133. PubMed ID: 35940125
[TBL] [Abstract][Full Text] [Related]
4. Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells.
Jiang G; Dallas-Yang Q; Liu F; Moller DE; Zhang BB
J Biol Chem; 2003 Jan; 278(1):180-6. PubMed ID: 12409308
[TBL] [Abstract][Full Text] [Related]
5. GPR43 deficiency protects against podocyte insulin resistance in diabetic nephropathy through the restoration of AMPKα activity.
Lu J; Chen PP; Zhang JX; Li XQ; Wang GH; Yuan BY; Huang SJ; Liu XQ; Jiang TT; Wang MY; Liu WT; Ruan XZ; Liu BC; Ma KL
Theranostics; 2021; 11(10):4728-4742. PubMed ID: 33754024
[No Abstract] [Full Text] [Related]
6. mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.
Inoki K; Mori H; Wang J; Suzuki T; Hong S; Yoshida S; Blattner SM; Ikenoue T; Rüegg MA; Hall MN; Kwiatkowski DJ; Rastaldi MP; Huber TB; Kretzler M; Holzman LB; Wiggins RC; Guan KL
J Clin Invest; 2011 Jun; 121(6):2181-96. PubMed ID: 21606597
[TBL] [Abstract][Full Text] [Related]
7. Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy.
Lennon R; Pons D; Sabin MA; Wei C; Shield JP; Coward RJ; Tavaré JM; Mathieson PW; Saleem MA; Welsh GI
Nephrol Dial Transplant; 2009 Nov; 24(11):3288-96. PubMed ID: 19556298
[TBL] [Abstract][Full Text] [Related]
8. Expression of SHP-1 induced by hyperglycemia prevents insulin actions in podocytes.
Drapeau N; Lizotte F; Denhez B; Guay A; Kennedy CR; Geraldes P
Am J Physiol Endocrinol Metab; 2013 Jun; 304(11):E1188-98. PubMed ID: 23531619
[TBL] [Abstract][Full Text] [Related]
9. Complement factor B in high glucose-induced podocyte injury and diabetic kidney disease.
Lu Q; Hou Q; Cao K; Sun X; Liang Y; Gu M; Xue X; Zhao AZ; Dai C
JCI Insight; 2021 Oct; 6(19):. PubMed ID: 34622800
[TBL] [Abstract][Full Text] [Related]
10. IκB kinase β (IKKβ) does not mediate feedback inhibition of the insulin signalling cascade.
Lancaster GI; Skiba B; Yang C; Nicholls HT; Langley KG; Chan MH; Bruce CR; Rewcastle GW; Shepherd PR; Karin M; Febbraio MA
Biochem J; 2012 Mar; 442(3):723-32. PubMed ID: 22364283
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes.
Gao Z; Zhang X; Zuberi A; Hwang D; Quon MJ; Lefevre M; Ye J
Mol Endocrinol; 2004 Aug; 18(8):2024-34. PubMed ID: 15143153
[TBL] [Abstract][Full Text] [Related]
12. Advanced glycation end-products suppress autophagic flux in podocytes by activating mammalian target of rapamycin and inhibiting nuclear translocation of transcription factor EB.
Zhao X; Chen Y; Tan X; Zhang L; Zhang H; Li Z; Liu S; Li R; Lin T; Liao R; Zhang Q; Dong W; Shi W; Liang X
J Pathol; 2018 Jun; 245(2):235-248. PubMed ID: 29570219
[TBL] [Abstract][Full Text] [Related]
13. Persistent Insulin Resistance in Podocytes Caused by Epigenetic Changes of SHP-1 in Diabetes.
Lizotte F; Denhez B; Guay A; Gévry N; Côté AM; Geraldes P
Diabetes; 2016 Dec; 65(12):3705-3717. PubMed ID: 27585521
[TBL] [Abstract][Full Text] [Related]
14. C1-Ten is a PTPase of nephrin, regulating podocyte hypertrophy through mTORC1 activation.
Lee J; Koh A; Jeong H; Kim E; Ha TS; Saleem MA; Ryu SH
Sci Rep; 2017 Sep; 7(1):12346. PubMed ID: 28955049
[TBL] [Abstract][Full Text] [Related]
15. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy.
Susztak K; Raff AC; Schiffer M; Böttinger EP
Diabetes; 2006 Jan; 55(1):225-33. PubMed ID: 16380497
[TBL] [Abstract][Full Text] [Related]
16. Independent role of PP2A and mTORc1 in palmitate induced podocyte death.
Kumar S; Tikoo K
Biochimie; 2015 May; 112():73-84. PubMed ID: 25724269
[TBL] [Abstract][Full Text] [Related]
17. Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor.
Lay AC; Hurcombe JA; Betin VMS; Barrington F; Rollason R; Ni L; Gillam L; Pearson GME; Østergaard MV; Hamidi H; Lennon R; Welsh GI; Coward RJM
Diabetologia; 2017 Nov; 60(11):2299-2311. PubMed ID: 28852804
[TBL] [Abstract][Full Text] [Related]
18. Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta.
Kim F; Tysseling KA; Rice J; Pham M; Haji L; Gallis BM; Baas AS; Paramsothy P; Giachelli CM; Corson MA; Raines EW
Arterioscler Thromb Vasc Biol; 2005 May; 25(5):989-94. PubMed ID: 15731493
[TBL] [Abstract][Full Text] [Related]
19. DUSP26 regulates podocyte oxidative stress and fibrosis in a mouse model with diabetic nephropathy through the mediation of ROS.
Huang F; Sheng XX; Zhang HJ
Biochem Biophys Res Commun; 2019 Jul; 515(3):410-416. PubMed ID: 31155289
[TBL] [Abstract][Full Text] [Related]
20. Mangiferin prevents diabetic nephropathy progression and protects podocyte function via autophagy in diabetic rat glomeruli.
Wang X; Gao L; Lin H; Song J; Wang J; Yin Y; Zhao J; Xu X; Li Z; Li L
Eur J Pharmacol; 2018 Apr; 824():170-178. PubMed ID: 29444469
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]