BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 33310289)

  • 1. Discovery of 7-aminophenanthridin-6-one as a new scaffold for matrix metalloproteinase inhibitors with multitarget neuroprotective activity.
    Rocchi D; Blázquez-Barbadillo C; Agamennone M; Laghezza A; Tortorella P; Vicente-Zurdo D; Rosales-Conrado N; Moyano P; Pino JD; González JF; Menéndez JC
    Eur J Med Chem; 2021 Jan; 210():113061. PubMed ID: 33310289
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-Activity Relationships of UTX-121 Derivatives for the Development of Novel Matrix Metalloproteinase-2/9 Inhibitors.
    Yamahana H; Komiya Y; Takino T; Endo Y; Yamada H; Asada C; Uto Y
    Chem Pharm Bull (Tokyo); 2021; 69(10):1017-1028. PubMed ID: 34602570
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New in Vivo Compatible Matrix Metalloproteinase (MMP)-2 and MMP-9 Inhibitors.
    Beutel B; Song J; Konken CP; Korpos E; Schinor B; Gerwien H; Vidyadharan R; Burmeister M; Li L; Haufe G; Sorokin L
    Bioconjug Chem; 2018 Nov; 29(11):3715-3725. PubMed ID: 30277751
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors.
    Laghezza A; Luisi G; Caradonna A; Di Pizio A; Piemontese L; Loiodice F; Agamennone M; Tortorella P
    Bioorg Med Chem; 2020 Feb; 28(3):115257. PubMed ID: 31874775
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Battle tactics against MMP-9; discovery of novel non-hydroxamate MMP-9 inhibitors endowed with PI3K/AKT signaling attenuation and caspase 3/7 activation via Ugi bis-amide synthesis.
    Ayoup MS; Fouad MA; Abdel-Hamid H; Ramadan ES; Abu-Serie MM; Noby A; Teleb M
    Eur J Med Chem; 2020 Jan; 186():111875. PubMed ID: 31740054
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fragment-Based Discovery of 5-Arylisatin-Based Inhibitors of Matrix Metalloproteinases 2 and 13.
    Agamennone M; Belov DS; Laghezza A; Ivanov VN; Novoselov AM; Andreev IA; Ratmanova NK; Altieri A; Tortorella P; Kurkin AV
    ChemMedChem; 2016 Sep; 11(17):1892-8. PubMed ID: 27418256
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, experimental evaluation and molecular modelling of hydroxamate derivatives as zinc metalloproteinase inhibitors.
    Sjøli S; Nuti E; Camodeca C; Bilto I; Rossello A; Winberg JO; Sylte I; Adekoya OA
    Eur J Med Chem; 2016 Jan; 108():141-153. PubMed ID: 26638045
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A pentanoic acid derivative targeting matrix metalloproteinase-2 (MMP-2) induces apoptosis in a chronic myeloid leukemia cell line.
    Mukherjee A; Adhikari N; Jha T
    Eur J Med Chem; 2017 Dec; 141():37-50. PubMed ID: 29028530
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pyridine-Containing Macrocycles Display MMP-2/9 Inhibitory Activity and Distinct Effects on Migration and Invasion of 2D and 3D Breast Cancer Models.
    Proença S; Antunes B; Guedes RC; Ramilo-Gomes F; Cabral MF; Costa J; Fernandes AS; Castro M; Oliveira NG; Miranda JP
    Int J Mol Sci; 2019 Oct; 20(20):. PubMed ID: 31618886
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinetic characterization of 4,4'-biphenylsulfonamides as selective non-zinc binding MMP inhibitors.
    Santamaria S; Nuti E; Cercignani G; La Regina G; Silvestri R; Supuran CT; Rossello A
    J Enzyme Inhib Med Chem; 2015 Dec; 30(6):947-54. PubMed ID: 25694065
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and discovery of (I-3,II-3)-biacacetin as a novel non-zinc binding inhibitor of MMP-2 and MMP-9.
    Nanjan P; Nambiar J; Nair BG; Banerji A
    Bioorg Med Chem; 2015 Jul; 23(13):3781-7. PubMed ID: 25907368
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An integrated computational and experimental approach to gaining selectivity for MMP-2 within the gelatinase subfamily.
    Fabre B; Filipiak K; Díaz N; Zapico JM; Suárez D; Ramos A; de Pascual-Teresa B
    Chembiochem; 2014 Feb; 15(3):399-412. PubMed ID: 24449516
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of highly potent and selective MMP2 inhibitors addressing the S1' subsite with d-proline-based compounds.
    Lenci E; Innocenti R; Di Francescantonio T; Menchi G; Bianchini F; Contini A; Trabocchi A
    Bioorg Med Chem; 2019 May; 27(9):1891-1902. PubMed ID: 30926311
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of Gelatinases (MMP-2 and MMP-9) by Withania somnifera Phytochemicals Confers Neuroprotection in Stroke: An In Silico Analysis.
    Kumar G; Patnaik R
    Interdiscip Sci; 2018 Dec; 10(4):722-733. PubMed ID: 28488219
    [TBL] [Abstract][Full Text] [Related]  

  • 15. N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.
    Nuti E; Cantelmo AR; Gallo C; Bruno A; Bassani B; Camodeca C; Tuccinardi T; Vera L; Orlandini E; Nencetti S; Stura EA; Martinelli A; Dive V; Albini A; Rossello A
    J Med Chem; 2015 Sep; 58(18):7224-40. PubMed ID: 26263024
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Robust design of some selective matrix metalloproteinase-2 inhibitors over matrix metalloproteinase-9 through in silico/fragment-based lead identification and de novo lead modification: Syntheses and biological assays.
    Adhikari N; Halder AK; Mallick S; Saha A; Saha KD; Jha T
    Bioorg Med Chem; 2016 Sep; 24(18):4291-4309. PubMed ID: 27452283
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sulfonamide derivatives containing dihydropyrazole moieties selectively and potently inhibit MMP-2/MMP-9: Design, synthesis, inhibitory activity and 3D-QSAR analysis.
    Yan XQ; Wang ZC; Li Z; Wang PF; Qiu HY; Chen LW; Lu XY; Lv PC; Zhu HL
    Bioorg Med Chem Lett; 2015 Oct; 25(20):4664-71. PubMed ID: 26346367
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and binding monitoring of a new nanomolar PAMAM-based matrix metalloproteinases inhibitor (MMPIs).
    Cerofolini L; Baldoneschi V; Dragoni E; Storai A; Mamusa M; Berti D; Fragai M; Richichi B; Nativi C
    Bioorg Med Chem; 2017 Jan; 25(2):523-527. PubMed ID: 27914947
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and preliminary bioactivity evaluations of 8-hydroxyquinoline derivatives as matrix metalloproteinase (MMP) inhibitors.
    Chen C; Yang X; Fang H; Hou X
    Eur J Med Chem; 2019 Nov; 181():111563. PubMed ID: 31415980
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual inhibitory pathways of metallofullerenol Gd@C₈₂(OH)₂₂ on matrix metalloproteinase-2: molecular insight into drug-like nanomedicine.
    Kang SG; Araya-Secchi R; Wang D; Wang B; Huynh T; Zhou R
    Sci Rep; 2014 Apr; 4():4775. PubMed ID: 24758941
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.