288 related articles for article (PubMed ID: 33315225)
1. Distal Regions Regulate Dihydrofolate Reductase-Ligand Interactions.
Goldstein M; Goodey NM
Methods Mol Biol; 2021; 2253():185-219. PubMed ID: 33315225
[TBL] [Abstract][Full Text] [Related]
2. Correlated motion and the effect of distal mutations in dihydrofolate reductase.
Rod TH; Radkiewicz JL; Brooks CL
Proc Natl Acad Sci U S A; 2003 Jun; 100(12):6980-5. PubMed ID: 12756296
[TBL] [Abstract][Full Text] [Related]
3. Multiple intermediates, diverse conformations, and cooperative conformational changes underlie the catalytic hydride transfer reaction of dihydrofolate reductase.
Arora K; Brooks CL
Top Curr Chem; 2013; 337():165-87. PubMed ID: 23420416
[TBL] [Abstract][Full Text] [Related]
4. Impact of distal mutations on the network of coupled motions correlated to hydride transfer in dihydrofolate reductase.
Wong KF; Selzer T; Benkovic SJ; Hammes-Schiffer S
Proc Natl Acad Sci U S A; 2005 May; 102(19):6807-12. PubMed ID: 15811945
[TBL] [Abstract][Full Text] [Related]
5. Structure, dynamics, and catalytic function of dihydrofolate reductase.
Schnell JR; Dyson HJ; Wright PE
Annu Rev Biophys Biomol Struct; 2004; 33():119-40. PubMed ID: 15139807
[TBL] [Abstract][Full Text] [Related]
6. Disruption of the crossover helix impairs dihydrofolate reductase activity in the bifunctional enzyme TS-DHFR from Cryptosporidium hominis.
Vargo MA; Martucci WE; Anderson KS
Biochem J; 2009 Feb; 417(3):757-64. PubMed ID: 18851711
[TBL] [Abstract][Full Text] [Related]
7. Analysis of hydride transfer and cofactor fluorescence decay in mutants of dihydrofolate reductase: possible evidence for participation of enzyme molecular motions in catalysis.
Farnum MF; Magde D; Howell EE; Hirai JT; Warren MS; Grimsley JK; Kraut J
Biochemistry; 1991 Dec; 30(49):11567-79. PubMed ID: 1747376
[TBL] [Abstract][Full Text] [Related]
8. Effect of mutation on enzyme motion in dihydrofolate reductase.
Watney JB; Agarwal PK; Hammes-Schiffer S
J Am Chem Soc; 2003 Apr; 125(13):3745-50. PubMed ID: 12656604
[TBL] [Abstract][Full Text] [Related]
9. Effect of Asp122 Mutation on the Hydride Transfer in E. coli DHFR Demonstrates the Goldilocks of Enzyme Flexibility.
Mhashal AR; Pshetitsky Y; Eitan R; Cheatum CM; Kohen A; Major DT
J Phys Chem B; 2018 Aug; 122(33):8006-8017. PubMed ID: 30040418
[TBL] [Abstract][Full Text] [Related]
10. Network of coupled promoting motions in enzyme catalysis.
Agarwal PK; Billeter SR; Rajagopalan PT; Benkovic SJ; Hammes-Schiffer S
Proc Natl Acad Sci U S A; 2002 Mar; 99(5):2794-9. PubMed ID: 11867722
[TBL] [Abstract][Full Text] [Related]
11. Coupling interactions of distal residues enhance dihydrofolate reductase catalysis: mutational effects on hydride transfer rates.
Rajagopalan PT; Lutz S; Benkovic SJ
Biochemistry; 2002 Oct; 41(42):12618-28. PubMed ID: 12379104
[TBL] [Abstract][Full Text] [Related]
12. A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis.
Bhabha G; Lee J; Ekiert DC; Gam J; Wilson IA; Dyson HJ; Benkovic SJ; Wright PE
Science; 2011 Apr; 332(6026):234-8. PubMed ID: 21474759
[TBL] [Abstract][Full Text] [Related]
13. Structure-based analysis of Bacilli and plasmid dihydrofolate reductase evolution.
Alotaibi M; Reyes BD; Le T; Luong P; Valafar F; Metzger RP; Fogel GB; Hecht D
J Mol Graph Model; 2017 Jan; 71():135-153. PubMed ID: 27914300
[TBL] [Abstract][Full Text] [Related]
14. Probing the role of parasite-specific, distant structural regions on communication and catalysis in the bifunctional thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum.
Dasgupta T; Anderson KS
Biochemistry; 2008 Feb; 47(5):1336-45. PubMed ID: 18189414
[TBL] [Abstract][Full Text] [Related]
15. A glutamine 67--> histidine mutation in homotetrameric R67 dihydrofolate reductase results in four mutations per single active site pore and causes substantial substrate and cofactor inhibition.
Park H; Bradrick TD; Howell EE
Protein Eng; 1997 Dec; 10(12):1415-24. PubMed ID: 9543003
[TBL] [Abstract][Full Text] [Related]
16. Evidence for a functional role of the dynamics of glycine-121 of Escherichia coli dihydrofolate reductase obtained from kinetic analysis of a site-directed mutant.
Cameron CE; Benkovic SJ
Biochemistry; 1997 Dec; 36(50):15792-800. PubMed ID: 9398309
[TBL] [Abstract][Full Text] [Related]
17. Kinetic and structural characterization of dihydrofolate reductase from Streptococcus pneumoniae.
Lee J; Yennawar NH; Gam J; Benkovic SJ
Biochemistry; 2010 Jan; 49(1):195-206. PubMed ID: 19950924
[TBL] [Abstract][Full Text] [Related]
18. Preservation of protein dynamics in dihydrofolate reductase evolution.
Francis K; Stojkovic V; Kohen A
J Biol Chem; 2013 Dec; 288(50):35961-8. PubMed ID: 24158440
[TBL] [Abstract][Full Text] [Related]
19. Searching sequence space: two different approaches to dihydrofolate reductase catalysis.
Howell EE
Chembiochem; 2005 Apr; 6(4):590-600. PubMed ID: 15812782
[TBL] [Abstract][Full Text] [Related]
20. Increased substrate affinity in the Escherichia coli L28R dihydrofolate reductase mutant causes trimethoprim resistance.
Abdizadeh H; Tamer YT; Acar O; Toprak E; Atilgan AR; Atilgan C
Phys Chem Chem Phys; 2017 May; 19(18):11416-11428. PubMed ID: 28422217
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
