BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

372 related articles for article (PubMed ID: 33322084)

  • 1. Genome-Wide Analysis of Off-Target CRISPR/Cas9 Activity in Single-Cell-Derived Human Hematopoietic Stem and Progenitor Cell Clones.
    Smith RH; Chen YC; Seifuddin F; Hupalo D; Alba C; Reger R; Tian X; Araki D; Dalgard CL; Childs RW; Pirooznia M; Larochelle A
    Genes (Basel); 2020 Dec; 11(12):. PubMed ID: 33322084
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeted genome engineering in human induced pluripotent stem cells from patients with hemophilia B using the CRISPR-Cas9 system.
    Lyu C; Shen J; Wang R; Gu H; Zhang J; Xue F; Liu X; Liu W; Fu R; Zhang L; Li H; Zhang X; Cheng T; Yang R; Zhang L
    Stem Cell Res Ther; 2018 Apr; 9(1):92. PubMed ID: 29625575
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9.
    Mandal PK; Ferreira LM; Collins R; Meissner TB; Boutwell CL; Friesen M; Vrbanac V; Garrison BS; Stortchevoi A; Bryder D; Musunuru K; Brand H; Tager AM; Allen TM; Talkowski ME; Rossi DJ; Cowan CA
    Cell Stem Cell; 2014 Nov; 15(5):643-52. PubMed ID: 25517468
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FokI-dCas9 mediates high-fidelity genome editing in pigs.
    Fisicaro N; Salvaris EJ; Philip GK; Wakefield MJ; Nottle MB; Hawthorne WJ; Cowan PJ
    Xenotransplantation; 2020 Jan; 27(1):e12551. PubMed ID: 31407391
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ultra-deep sequencing validates safety of CRISPR/Cas9 genome editing in human hematopoietic stem and progenitor cells.
    Cromer MK; Barsan VV; Jaeger E; Wang M; Hampton JP; Chen F; Kennedy D; Xiao J; Khrebtukova I; Granat A; Truong T; Porteus MH
    Nat Commun; 2022 Aug; 13(1):4724. PubMed ID: 35953477
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Whole-genome sequencing reveals rare off-target mutations in CRISPR/Cas9-edited grapevine.
    Wang X; Tu M; Wang Y; Yin W; Zhang Y; Wu H; Gu Y; Li Z; Xi Z; Wang X
    Hortic Res; 2021 May; 8(1):114. PubMed ID: 33931634
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Low incidence of SNVs and indels in trio genomes of Cas9-mediated multiplex edited sheep.
    Wang X; Liu J; Niu Y; Li Y; Zhou S; Li C; Ma B; Kou Q; Petersen B; Sonstegard T; Huang X; Jiang Y; Chen Y
    BMC Genomics; 2018 May; 19(1):397. PubMed ID: 29801435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Combining Off-flow, a Nextflow-coded program, and whole genome sequencing reveals unintended genetic variation in CRISPR/Cas-edited iPSCs.
    Shum C; Han SY; Thiruvahindrapuram B; Wang Z; de Rijke J; Zhang B; Sundberg M; Chen C; Buttermore ED; Makhortova N; Howe J; Sahin M; Scherer SW
    Comput Struct Biotechnol J; 2024 Dec; 23():638-647. PubMed ID: 38283851
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Versatile Tool for the Quantification of CRISPR/Cas9-Induced Genome Editing Events in Human Hematopoietic Cell Lines and Hematopoietic Stem/Progenitor Cells.
    Jayavaradhan R; Pillis DM; Malik P
    J Mol Biol; 2019 Jan; 431(1):102-110. PubMed ID: 29751014
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Whole genome sequencing reveals rare off-target mutations and considerable inherent genetic or/and somaclonal variations in CRISPR/Cas9-edited cotton plants.
    Li J; Manghwar H; Sun L; Wang P; Wang G; Sheng H; Zhang J; Liu H; Qin L; Rui H; Li B; Lindsey K; Daniell H; Jin S; Zhang X
    Plant Biotechnol J; 2019 May; 17(5):858-868. PubMed ID: 30291759
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Whole-Genome Sequencing Reveals Rare Off-Target Mutations in
    Li Z; Lan J; Shi X; Lu T; Hu X; Liu X; Chen Y; He Z
    CRISPR J; 2024 Feb; 7(1):29-40. PubMed ID: 38353621
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A ribonucleoprotein transfection strategy for CRISPR/Cas9-mediated gene editing and single cell cloning in rainbow trout cells.
    Zoppo M; Okoniewski N; Pantelyushin S; Vom Berg J; Schirmer K
    Cell Biosci; 2021 Jun; 11(1):103. PubMed ID: 34082820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CRISPR based targeted genome editing of Chlamydomonas reinhardtii using programmed Cas9-gRNA ribonucleoprotein.
    Dhokane D; Bhadra B; Dasgupta S
    Mol Biol Rep; 2020 Nov; 47(11):8747-8755. PubMed ID: 33074412
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences.
    Stamatiadis P; Boel A; Cosemans G; Popovic M; Bekaert B; Guggilla R; Tang M; De Sutter P; Van Nieuwerburgh F; Menten B; Stoop D; Chuva de Sousa Lopes SM; Coucke P; Heindryckx B
    Hum Reprod; 2021 Apr; 36(5):1242-1252. PubMed ID: 33609360
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms.
    Farboud B; Jarvis E; Roth TL; Shin J; Corn JE; Marson A; Meyer BJ; Patel NH; Hochstrasser ML
    J Vis Exp; 2018 May; (135):. PubMed ID: 29889198
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification and Validation of CRISPR/Cas9 Off-Target Activity in Hematopoietic Stem and Progenitor Cells.
    Park SH; Lee CM; Bao G
    Methods Mol Biol; 2022; 2429():281-306. PubMed ID: 35507169
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cas9HF1 enhanced specificity in Ustilago maydis.
    Zuo W; Depotter JR; Doehlemann G
    Fungal Biol; 2020; 124(3-4):228-234. PubMed ID: 32220383
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells.
    Vakulskas CA; Dever DP; Rettig GR; Turk R; Jacobi AM; Collingwood MA; Bode NM; McNeill MS; Yan S; Camarena J; Lee CM; Park SH; Wiebking V; Bak RO; Gomez-Ospina N; Pavel-Dinu M; Sun W; Bao G; Porteus MH; Behlke MA
    Nat Med; 2018 Aug; 24(8):1216-1224. PubMed ID: 30082871
    [TBL] [Abstract][Full Text] [Related]  

  • 19. No off-target mutations in functional genome regions of a CRISPR/Cas9-generated monkey model of muscular dystrophy.
    Wang S; Ren S; Bai R; Xiao P; Zhou Q; Zhou Y; Zhou Z; Niu Y; Ji W; Chen Y
    J Biol Chem; 2018 Jul; 293(30):11654-11658. PubMed ID: 29941452
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A stable DNA-free screening system for CRISPR/RNPs-mediated gene editing in hot and sweet cultivars of Capsicum annuum.
    Kim H; Choi J; Won KH
    BMC Plant Biol; 2020 Oct; 20(1):449. PubMed ID: 33004008
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.