BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

391 related articles for article (PubMed ID: 33322134)

  • 1. The Inhibition of Prolyl Oligopeptidase as New Target to Counteract Chronic Venous Insufficiency: Findings in a Mouse Model.
    Casili G; Lanza M; Scuderi SA; Messina S; Paterniti I; Campolo M; Esposito E
    Biomedicines; 2020 Dec; 8(12):. PubMed ID: 33322134
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The protective role of prolyl oligopeptidase (POP) inhibition in acute lung injury induced by intestinal ischemia-reperfusion.
    Casili G; Scuderi SA; Lanza M; Filippone A; Basilotta R; Mannino D; Campolo M; Esposito E; Paterniti I
    Oncotarget; 2021 Aug; 12(17):1663-1676. PubMed ID: 34434495
    [TBL] [Abstract][Full Text] [Related]  

  • 3. KYP-2047, an Inhibitor of Prolyl-Oligopeptidase, Reduces GlioBlastoma Proliferation through Angiogenesis and Apoptosis Modulation.
    Scuderi SA; Casili G; Ardizzone A; Forte S; Colarossi L; Sava S; Paterniti I; Esposito E; Cuzzocrea S; Campolo M
    Cancers (Basel); 2021 Jul; 13(14):. PubMed ID: 34298658
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prolyl oligopeptidase inhibition ameliorates experimental pulmonary fibrosis both in vivo and in vitro.
    Cucinotta L; Mannino D; Casili G; Repici A; Crupi L; Paterniti I; Esposito E; Campolo M
    Respir Res; 2023 Aug; 24(1):211. PubMed ID: 37626373
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Beneficial effect of KYP-2047, a propyl-oligopeptidase inhibitor, on oral squamous cell carcinoma.
    Scuderi SA; Casili G; Filippone A; Lanza M; Basilotta R; Giuffrida R; Munaò S; Colarossi L; Capra AP; Esposito E; Paterniti I
    Oncotarget; 2021 Dec; 12(25):2459-2473. PubMed ID: 34917264
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prolyl oligopeptidase induces angiogenesis both in vitro and in vivo in a novel regulatory manner.
    Myöhänen TT; Tenorio-Laranga J; Jokinen B; Vázquez-Sánchez R; Moreno-Baylach MJ; García-Horsman JA; Männistö PT
    Br J Pharmacol; 2011 Aug; 163(8):1666-78. PubMed ID: 21133893
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of Prolyl Oligopeptidase Restores Spontaneous Motor Behavior in the α-Synuclein Virus Vector-Based Parkinson's Disease Mouse Model by Decreasing α-Synuclein Oligomeric Species in Mouse Brain.
    Svarcbahs R; Julku UH; Myöhänen TT
    J Neurosci; 2016 Dec; 36(49):12485-12497. PubMed ID: 27927963
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Therapeutic potential of flavonoids in the treatment of chronic venous insufficiency.
    Casili G; Lanza M; Campolo M; Messina S; Scuderi S; Ardizzone A; Filippone A; Paterniti I; Cuzzocrea S; Esposito E
    Vascul Pharmacol; 2021 Apr; 137():106825. PubMed ID: 33278582
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Prolyl Oligopeptidase Inhibitor KYP-2047 Is Cytoprotective and Anti-Inflammatory in Human Retinal Pigment Epithelial Cells with Defective Proteasomal Clearance.
    Toppila M; Hytti M; Korhonen E; Ranta-Aho S; Harju N; Forsberg MM; Kaarniranta K; Jalkanen A; Kauppinen A
    Antioxidants (Basel); 2023 Jun; 12(6):. PubMed ID: 37372009
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of Prolyl Oligopeptidase Prevents Consequences of Reperfusion following Intestinal Ischemia.
    Filippone A; Casili G; Ardizzone A; Lanza M; Mannino D; Paterniti I; Esposito E; Campolo M
    Biomedicines; 2021 Sep; 9(10):. PubMed ID: 34680471
    [TBL] [Abstract][Full Text] [Related]  

  • 11. KYP-2047 penetrates mouse brain and effectively inhibits mouse prolyl oligopeptidase.
    Jalkanen AJ; Leikas JV; Forsberg MM
    Basic Clin Pharmacol Toxicol; 2014 Jun; 114(6):460-3. PubMed ID: 24350801
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Brain pharmacokinetics of two prolyl oligopeptidase inhibitors, JTP-4819 and KYP-2047, in the rat.
    Jalkanen AJ; Hakkarainen JJ; Lehtonen M; Venäläinen T; Kääriäinen TM; Jarho E; Suhonen M; Forsberg MM
    Basic Clin Pharmacol Toxicol; 2011 Dec; 109(6):443-51. PubMed ID: 21707925
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Extracellular prolyl oligopeptidase derived from activated microglia is a potential neuroprotection target.
    Natunen TA; Gynther M; Rostalski H; Jaako K; Jalkanen AJ
    Basic Clin Pharmacol Toxicol; 2019 Jan; 124(1):40-49. PubMed ID: 29998529
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dermal tissue fibrosis in patients with chronic venous insufficiency is associated with increased transforming growth factor-beta1 gene expression and protein production.
    Pappas PJ; You R; Rameshwar P; Gorti R; DeFouw DO; Phillips CK; Padberg FT; Silva MB; Simonian GT; Hobson RW; Durán WN
    J Vasc Surg; 1999 Dec; 30(6):1129-45. PubMed ID: 10587400
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of novel (123)I-labeled 4-(4-iodophenyl)butanoyl-L-prolyl-(2S)-pyrrolidines for imaging prolyl oligopeptidase in vivo.
    Kallinen A; Todorov B; Kallionpää R; Bäck S; Sarparanta M; Raki M; García-Horsman JA; Bergström KA; Wallén EA; Männistö PT; Airaksinen AJ
    Eur J Med Chem; 2014 May; 79():436-45. PubMed ID: 24763264
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Behavior of Smooth Muscle Cells under Hypoxic Conditions: Possible Implications on the Varicose Vein Endothelium.
    Ortega MA; Romero B; Asúnsolo Á; Sainz F; Martinez-Vivero C; Álvarez-Mon M; Buján J; García-Honduvilla N
    Biomed Res Int; 2018; 2018():7156150. PubMed ID: 30498761
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prolyl oligopeptidase inhibition attenuates the toxicity of a proteasomal inhibitor, lactacystin, in the alpha-synuclein overexpressing cell culture.
    Myöhänen TT; Norrbacka S; Savolainen MH
    Neurosci Lett; 2017 Jan; 636():83-89. PubMed ID: 27818354
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prolyl oligopeptidase inhibition decreases extracellular acetylcholine levels in rat hippocampus and prefrontal cortex.
    Jalkanen AJ; Leikas JV; Forsberg MM
    Neurosci Lett; 2014 Sep; 579():110-3. PubMed ID: 25064702
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overexpression of transforming growth factor-beta1 correlates with increased synthesis of nitric oxide synthase in varicose veins.
    Jacob T; Hingorani A; Ascher E
    J Vasc Surg; 2005 Mar; 41(3):523-30. PubMed ID: 15838489
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prolyl oligopeptidase regulates progesterone secretion via the ERK signaling pathway in murine luteal cells.
    Xu P; Bao R; Zhang Y; Lu E; Feng F; Zhang L; Li J; Wang J; Tan X; Tang M; Hu C; Li G; Zhang C
    Mol Reprod Dev; 2019 Jun; 86(6):714-726. PubMed ID: 30990944
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.